| 2006-08-02 |
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Receptors In The Mouse Nose May Be Pheromone Detectors
Biologists have discovered a second set of olfactory receptors in the mouse nose, including ones that may detect pheromones and might therefore aid in the mating game.
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Choosing Face
Study clarifies the role of particular neurons in a region of monkeys' brains known to be important for object recognition.
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Active Sites Of A Hepatitis C Virus Enzyme Revealed
The crystal structure of one of the hepatitis C viral proteins could offer new opportunities for antiviral drug design.
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Unexpected Inheritance
Research supports the idea that RNA partly determines the inherited characteristics of plants and animals.
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Melanoma Risk Linked to the Gene for the Melanocortin-1 Receptor and Sun Exposure
MC1R gene variants are correlated with BRAF mutations and the risk of melanoma with intermittent exposure to sunlight.
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| 2006-08-01 |
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A Full Pipeline of Follow-on TNF-Antagonists
The US$ 7.6 bln market of TNF-antagonists attracts numerous follow-on compounds including improved TNF-antagonists and molecules originating from new technologies
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| 2006-07-31 |
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New Genomes to be Targetted for Sequencing
United States' National Human Genome Research Institute Large Scale Sequencing Research Network adds more animal genomes to it's To Do List.
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New Blood Test for the Prediction and Complications of Sickle Cell Disease
Brain natriuretic peptide or BNP is a hormone whose levels might also correlate with the severity of pulmonary hypertension and risk of death in sickle cell patients.
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| 2006-07-20 |
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Brain-Machine Interfaces - Recent Advances
Nature Web Focus includes exclusive interviews and video footage of experiments, alongside papers that paved the way for these recent advances.
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Cold Sore Virus Can Evade The Immune System
A newly identified method deployed by viruses to escape the immune system is reported.
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Alternative Genetic Cause Of Devastating Dementia
Two groups of neuroscientists have uncovered a mutation that can cause frontotemporal dementia (FTD).
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Making Cancer Stem Cells
Researchers show how cancer-triggering oncogenes can allow blood cells to acquire this ability and thus become leukaemia stem cells.
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Surprisingly, DNA Has Trouble Unwinding
If you stretch the helical structure of DNA, it actually winds itself more tightly.
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Co-Transplantation Of Bone Marrow Stromal Cells Transduced With IL-7 Gene Enhances Immune Reconstitution After Allogeneic Bone Marrow Transplantation
The use of MSC-IL-7 cells may be therapeutically useful for enhancing immune reconstitution without aggravating graft-versus-host disease (GVHD) in allo-BMT mice.
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Plasmid-Mediated VEGF Gene Transfer Induces Cardiomyogenesis And Reduces Myocardial Infarct Size In Sheep
VEGF gene transfer could also modify the evolution of experimental myocardial infarct.
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A Linkage of Two JNK Isoforms With Obesity and Insulin Resistance
The total activity of two isoforms of c-Jun N-terminal kinase is correlated with development of obesity and insulin resistance.
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| 2006-07-11 |
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Gender: Its not how you look, its how you express yourself
A UCLA study finds that the same genes express differently in males and females; discovery may explain gender gap in disease risk and drug response
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| 2006-07-07 |
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Prion Disease Infectivity May Yield New Mouse Model for Heart Diseases
Laboratory mice infected with the agent of scrapie show high levels of the scrapie agent in their heart several hundred days after being infected in the brain yielding a potential animal model to study heart amyloidosis.
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The Risk for Melanoma Possibly Inherited
Scientists Identify an Inherited Gene That Strongly Affects Risk for the Most Common Form of Melanoma
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| 2006-07-06 |
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Hearing’s Missing Link May Be a Protein Tied to Usher Syndrome
Protocadherin-15 is a likely player in the split-second reaction in which sound is converted into electrical signals. The findings may help elucidate why some people temporarily lose their hearing after being exposed to loud noise.
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Dopamine drug leads to neuronal replacement: a cure for Parkinson's Disease?
In preliminary results, researchers have shown that a drug, which mimics the effects of dopamine, causes new neurons to develop in the part of the brain where cells are lost in Parkinson's disease (PD).
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Regulation of Microglial Neurotoxicity
CX3CR1 signaling pathway is implicated in three models involving neurotoxicity: systemic inflammation, Parkinson’s disease, and ALS.
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| 2006-07-05 |
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Free Access To Nature Protocols
Available Online Till The End Of July.
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Gene Transfer Of RANTES And MCP-1 Chemokine Antagonists Prolongs Cardiac Allograft Survival
Research suggests a role for anti-chemokine gene therapy as an adjuvant therapy in heart transplantation.
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Sequencing Of The Reannotated Lmnb2 Gene Reveals Novel Mutations In Patients With Acquired Partial Lipodystrophy
Authors sequence LMNB2 as a candidate gene in nine white patients with acquired partial lipodystrophy (APL, also called "Barraquer-Simons syndrome").
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Localization Of Candidate Regions For A Novel Gene For Kartagener Syndrome
Research data provide a basis for the identification of a novel gene implicated in Kartagener syndrome.
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Exploring The Logic Of Neural Cell Development
Sceintists report on a revolutionary technology to explore and identify the complex molecular signals that determine the fate of precursor cells of the human brain.
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Science And Security In The Twenty-First Century
The 2006 special issue of EMBO Reports on Science & Security covers the social, economic and ethical impact of dual-use research in the life sciences on society and vice versa.
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Genes, Not Environment Determine Physical Activity Levels In Children
'Activity genes' that children are born with influence their physical activity levels more than environmental factors.
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Understanding The Causes Of Obesity
The amount of sleep a person has, or their exposure to air conditioning may be as important causes of obesity as diet and exercise.
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Clostridium difficile Genome
The genome sequence of Clostridium difficile, a major hospital acquired human pathogen, is published.
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A Malaria Drug For Underdeveloped Countries
Scientists have found a drug that can be used to control malaria infection.
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New Class Of Cancer Therapeutic
Scientists have created a new class of cancer drug that combines the targeting strength of one type of ribonucleic acid (RNA) therapy with the therapeutic potency of another.
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Stem Cells: Hopes And Realities
Insight articles provide an overview of the field of stem cell biology and its promise.
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Stimulating Stem Cells Fights Stroke Damage
Scientists show that stimulating a specific signalling pathway in the neural stem cells of rat brain can help the animals recover movement after a simulated stroke.
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Thymus Bipotent Precursor Cells Found
Researchers have discovered that a single precursor cell can form both major cell types of the thymus.
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T-Cell Link To Cancer
A link has been found between a particular type of gastrointestinal cancer and T-cell functioning.
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| 2006-06-29 |
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New Clues for Treatment of Liver Cancer
Study Implicates Two Human Genes in the Third Leading Cause of Cancer Deaths
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| 2006-06-28 |
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Neurons Grown from Embryonic Stem Cells Restore Function in Paralyzed Rats
First evidence of embryonic stem cell-derived motor neuron transplants in the spinal cord connecting with muscles and partially restoring function in paralyzed animals.
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| 2006-06-26 |
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Mitochondrail gene linked to Rett Syndrome
Abnormally high levels of a protein called Uqcrc1 in the brains of mouse models of Rett Syndrome cause mitochondria to work overtime, forming an energetic disequalibrium potentially toxic to neurons.
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| 2006-06-23 |
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NGF accelerates corneal wound healing
In a recent online report, researchers have shown surprising corneal wounds healing acceleration by topical addition of nerve growth factor.
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| 2006-06-22 |
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Gene discovery points to Iron build-up as a major neuronal toxin
Oregon Health & Science University researchers have identified the gene behind a group of rare, progressive childhood disorders caused by an abnormal buildup of iron in the brain.
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| 2006-06-21 |
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Tuning Out The Noise
Over-exposure to irrelevant sounds can cause the brain to tune them out in favor of other auditory stimuli.
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Predicting Other's Actions Starts Young
Babies as young as one can learn to predict the outcome of another person's actions as well as adults can.
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How B Cells Mature
Researchers have identified an essential protein for B cell maturation, a process required for this immune cell to become functional.
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Lifeline For Aging Cells
Scientists have found a small molecule that can be used to extend the lifespan of mammalian cells.
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Tumor Homing Device
Scientists have developed a tool that can be used for diagnostic imaging and targeted therapy of tumors.
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Self-Renewal Understood
Molecule identified that endows embryonic stem (ES) cells with the abilities to self-renew and to make numerous other cell types.
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Secret To Self-Renewal
Analysis of the contribution of a large number of candidate genes important for regulating cell differentiation.
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Two Research Reports OnThe Use of Gene Therapy In The Prevention And Treatment Of Prostate Cancer.
Two groups have published their research findings regarding the use of gene therapy in the prevention and treatment of prostate cancer.
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