| 2005-07-19 |
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Mouse Studies of Oseltamivir Show Promise Against H5N1 Influenza Virus
Experiments in mice show that an antiviral drug currently used against annual influenza strains also can suppress the deadly influenza virus that has spread from birds to humans.
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Complementary and Alternative Medicine - Online Education
New Online Continuing Education Series on Complementary and Alternative Medicine from the NIH.
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| 2005-07-15 |
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HIV Therapy Greatly Extends Life of Key T Cells
Interleukin-2 (IL-2), can increases the lifespan of certain subsets of immune system T cells in some HIV-positive people.
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| 2005-07-14 |
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Three Deadly Parasite Genomes Sequenced
Sequenced: African sleeping sickness, leishmaniasis and Chagas disease.
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Menopause Symptoms May Come Back After Stopping Menopausal Hormone Therapy
A closer look at menopausal hormone therapy - the benefits may not outweigh the risks.
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Nitric Oxide Inhalation Therapy for Preterm Found Questionable
Inhaled nitric oxide therapy is effective for treating full term infants with lung complications; however, in preterm infants it does not reduce chances for death or further lung problems.
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| 2005-07-12 |
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Synthetic Biology Will Help Manage Nature's Biothreats
Synthetic biology may help to manage even greater biological threats from nature, so banning this technology is likely to cause more harm than good.
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Genetic Influences On Anxiety
Brain areas involved in anxiety have abnormal activity in individuals with Williams syndrome.
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Understanding A Side Effect Of TZDs
Mechanism underlying the side effect of Thiazolidinediones - systemic fluid retention - is explained.
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SARS Receptor Identified In Vivo
Angiotensin-converting enzyme 2 (ACE2) is a crucial receptor of the severe acute respiratory syndrome (SARS) virus in vivo.
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Growth Factor Brings Back Hope To Parkinson Patients
Infusion of glial cell line-derived neurotrophic factor (GDNF) into the brain of people with Parkinson disease induces the growth of nerve fibers in one of the brain regions affected by this disorder.
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Adding up Tolls for Immune Cell
Researchers show that human immune cells integrate multiple signals obtained by 'tasting' their microbial invader through sensors known as Toll-like receptors (TLRs).
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TACI Is Mutant In Common Variable Immunodeficiency And IgA Deficiency
Two research studies present evidence for a new genetic factor underlying two human immunodeficiency syndromes.
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Fibrous Genetics
The identification of a gene contributing to the proliferation of fibrous tissue in the liver has been reported.
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Mechanism Of Motor Neuron Disease
A study reports a new mechanism underlying motor neuron disease.
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An Amplified Difference In Melanoma Cells
Scientists have found a distinct amplification of the gene encoding MITF (microphthalmia-associated transcription factor) in melanoma cells.
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Cigarette Brain Boost Inseparable From Addiction
New research in mice shows that the same brain system is involved in both stimulation and addiction, meaning that the two are unlikely to be separable.
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A Global View Of Cancer
Specific modifications of histones are linked to changes in gene expression, and have been found to be altered in cancer.
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The Dynamics Of A Human Cancer Revealed
A team of researchers has developed a mathematical model based on the biology of blood cell formation to describe how certain cancer cells respond to a molecularly targeted therapy.
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| 2005-07-06 |
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Scientists Discover How Nipah Virus Enters Cells
Nipah and Hendra viruses use a cell surface receptor, Ephrin-B2, as the doorway to get inside cells.
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Women’s Health Study Finds Vitamin E Does not Protect Women from Heart Attack, Stroke, or Cancer
Vitamin E supplements do not protect healthy women against heart attacks and stroke, according to a long-term clinical trial of the effect of vitamin E and aspirin on both the prevention of cardiovascular disease and of cancer.
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Protein Structure Initiative Advances to Rapid Production Phase
With the announcement of 10 new research centers, the Protein Structure Initiative (PSI) launches the second phase of its national effort to find the three-dimensional shapes of a wide range of proteins.
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Diuretics Effective for People with Diabetes and High Blood Pressure
Latest analysis of large clinical trial shows that among diabetics, the less costly diuretics are at least as effective and may be more beneficial for some people.
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Cancer Drug Slows Poxvirus in Mice
Gleevec might be useful as a preventive against adverse effects of smallpox vaccine.
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| 2005-06-28 |
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Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure
Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.
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Mutation In Mouse Circulatory Gene Mimics A Form Of Congenital Heart Disease
Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development.
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Geneticists identify 'master switch' that causes female flies to behave like males
Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour
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Thalassemia: Genetic Blood Disorder Expected To Double In Next Few Decades
Children's Hospital Oakland has formed an international network treating patients throughout the world.
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A Step Forward in Stem Cell Research
Derivation of Multipotent Mesenchymal Precursors from Human Embryonic Stem Cells
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Disability Rights, Prenatal Diagnosis and Eugenics: A Cross-Cultural View
This paper considers the disability rights critique of genetic testing in the context of different communities and the issue of nondirectiveness.
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Genetic Evaluation and Counseling of Couples with Recurrent Miscarriage
Recommendations of the National Society of Genetic Counselors
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New Role For BRCA1
A new function for the tumor suppressor gene BRCA1 in normal cells is described.
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Mechanism Of Motor Neuron Disease
Study reports a new mechanism underlying motor neuron disease, which may be broadly relevant to several adult-onset neurodegenerative diseases.
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Suppression Of Colorectal Cancer Progression
The expression of an intestinal epithelial cell receptor is silenced in most human colorectal cancers that progress from benign to malignant.
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Malignant Cells Exploit Vessel Structures
Researchers reveal how a specialized region of blood vessels can sustain malignant metastasis in the bone marrow.
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| 2005-06-24 |
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New Food Allergy Research Consortium Focuses on Peanut Allergy
Food Allergy Research Consortium strives to develop therapies to treat and prevent food allergies.
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Researchers Debut New X-Ray Resources for Studying Molecules
The most powerful X-ray beams in the Western Hemisphere become available at the Argonne National Laboratory.
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NIAID Scientists Unveil Mechanism Behind Resistance to Severe Malaria
Scientists have discovered why people with type C hemoglobin are less prone to severe malaria.
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Adult Antisocial Syndromes Common Among Substance Abusers
Data from a recent epidemiologic survey of more than 43,000 U.S. adults show that antisocial syndromes are more common among people with substance abuse disorders than those without these disorders.
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Five Topics Regarding Vision Added to NIHSeniorHealth Web Site
Eye diseases and conditions leading to vision loss increase significantly with age. Read about them on the NIHSeniorHealth Web Site.
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| 2005-06-16 |
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Promising New TB Drug Enters Clinical Trial
The novel antibiotic, PA-824, may shorten the time needed to treat tuberculosis.
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Rodent Social Behavior Encoded in Junk DNA
Junk DNA holds sequence for key hormone receptor involved in determining male-female relations and parenting behaviors in a species of voles.
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US$3.68 Million Grant to Boost Public Health “Informatics”
New National Library of Medicine and Robert Wood Johnson Foundation Partnership Will Develop More Public Health Information Experts
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NIH Selects 13 More Organisms for Genome Sequencing
The National Human Genome Research Institute (NHGRI) adds gibbon, bats, finch and mosquito strains to strategic mix.
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| 2005-06-14 |
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New Gene Shows Way For Autoimmune Disease
A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
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Tagging Pathogens With Synthetic DNA 'Barcodes'
Researchers make synthetic DNA 'barcodes' to tag pathogens, providing an inexpensive, off-the-shelf monitoring system
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New Threat Of Antimalarial Resistance
Researchers reveal the basis of the selectivity of Artemisinins, the last line of defense against drug-resistant malaria parasites.
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New Culture System To Study Hepatitis C Virus
Scientists report on the development of the first system that supports complete replication of hepatitis C virus (HCV).
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Vaccine Against Ebola And Marburg Viruses Effective In Primates
Paper reports the development of a vaccine that successfully protects non-human primates against Ebola and Marburg viruses.
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Editing Cancer
Scientists report that type I interferon, a chemical messenger, is an important component of the immune process, now called 'cancer immunoediting'.
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