home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Secret To Self-Renewal

  June, 21 2006 7:40
your information resource in human molecular genetics
In a paper published online by Nature, Ihor Lemischka and colleagues use a global approach to analyse the contribution of a large number of candidate genes important for regulating cell differentiation.

They use short hairpin RNAs to block candidate genes in embryonic stem (ES) cells, and identify seven genes important for self-renewal. They show how the products of these genes interact, and use gene expression analyses to show that blocking each one makes the ES cells differentiate into particular tissue types.

These molecules may be important in endowing ES cells with their revered properties the ability to self-renew and the potential to make many other cell types.


Ihor Lemischka (Princeton University, NJ, USA)
E-mail: ilemischka@molbio.princeton.edu

Abstract available online.

(C) Nature press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.