| 2004-02-03 |
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Bringing Nerve Cells Together
The initial formation of the synaptic connections that enable neurons to communicate with each other is a complex process, with newly formed synapses helping to direct how a dendrite will grow.
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Anti-Obesity Drugs Could Increase Risk Of Colorectal Cancer
Compounds being developed into drugs to treat atherosclerosis and obesity may put patients at risk for colorectal cancer.
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Tumor Treatment Blocks Blood Vessels
Scientists highlight the effects of bevacizumab (Avastin), an antibody that inactivates VEGF, on blood vessels in rectal tumors.
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Cerebral Malaria Often Misdiagnosed
The findings in this study will be important for correctly identifying cerebral malaria patients for future clinical trials and have new implications for diagnosing cerebral malaria.
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Protecting Baby
A systemic change occurs in the immune systems of pregnant women that lessens the possibility of fetal rejection as well as other potentially harmful autoimmune reactions.
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Down Syndrome Gene Helps Brain Cells Connect
Every one of the trillion cells in the brain may have a unique identity, assigned by a gene called Dscam, and the same gene in humans has been implicated in Down syndrome.
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Complete Picture Of A Human Immune Pathway
This snapshot of the hundreds of interactions involved provides the most complete and realistic picture to date of how this regulatory system functions, and identifies many potential targets for therapeutic intervention.
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Maternal Diet Affects Offspring Longevity In Mice
This finding may have implications for pregnant and breast-feeding human mothers.
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| 2004-01-29 |
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Genetic Screening Recommended to Detect New Neurodegenerative Disorder in Men Over 50
Common and small mutation in the fragile X gene, once thought to have no health effects in male carriers, now linked to tremors, balance problems and memory deficits.
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New Method Identifies Human microRNA Targets
Research into the mechanics of microRNAs, tiny molecules that can selectively silence genes, has revealed a new mode of gene regulation that scientists believe has a broad impact on both plant and animal cells.
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| 2004-01-27 |
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Low Free Testosterone Levels Linked to Alzheimer’s Disease in Older Men
Older men with lower levels of free testosterone circulating in their bloodstreams could be at higher risk of developing Alzheimer’s disease
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Transgenic Animals Produced Using Cultured Sperm
Study Opens New Possibilities for Biological Research, Gene Therapy
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First U.S. Tuberculosis Vaccine Trial in 60 Years Begins
A new vaccine, made with several proteins from the bacterium that causes tuberculosis (TB), will soon enter the first phase of human safety testing.
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Gene Therapy in Salivary Glands
Gene Therapy in Salivary Glands Could Lead to Promising Applications in Oral Diseases
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| 2004-01-26 |
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Perlegen Sciences and Galileo Genomics Form Collaboration to Determine the Genetic Basis of 21 Common Diseases
Both companies announced a collaboration to rapidly develop a Quebec Linkage Disequilibrium Map (QLDM) consisting of approximately 40,000 SNPs chosen to represent the specific patterns of linkage disequilibrium in the Quebec Founder Population.
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Researchers develop computer application to 'read' medical literature
The software, called IRIDESCENT, constructs a network of related objects starting with their co-occurrence within MEDLINE abstracts.
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European Virtual Institute for Genome Annotation
The Commission of the European Union has awarded 12,000,000 Euro to 24 bioinformatics groups based in 14 countries throughout Europe to create a pan-European BioSapiens Network of Excellence in Bioinformatics.
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One dose of "designer" gene therapy may target specific body area
Doctors may soon be able to inject gene therapy intravenously that travels to a specific part of the body.
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| 2004-01-15 |
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Lexicon Genetics has Initiated More Than 40 Drug Discovery Programs from its Genome5000(TM) Program
These drug discovery programs are in the fields of diabetes, obesity, cardiovascular disease, psychiatric and neurological disorders, cancer, immune system disorders and ophthalmic disease.
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Ancient DNA mutations permitted humans to adapt to colder climates
Changes in cells’ mitochondria may explain current predispositions to common diseases
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Gene May Be Key To Evolution Of Larger Human Brain
Researchers have identified a gene that appears to have played a role in the expansion of the human brain’s cerebral cortex.
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| 2004-01-12 |
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Future of Cancer Diagnosis
Treatment Lies in Tumor "Barcode"
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| 2004-01-09 |
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Research reveals brain has biological mechanism to block unwanted memories
For the first time, researchers at Stanford University and the University of Oregon have shown that a biological mechanism exists in the human brain to block unwanted memories.
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| 2004-01-08 |
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First gene therapy approved
China's medicines authority approved Gendicine, a cancer therapy, after it achieved promising results in a clinical trial.
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| 2004-01-06 |
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Young nerve cells can rewind their developmental clocks
Scientists have identified a gene in the cerebral cortex that apparently controls the developmental clock of embryonic nerve cells.
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A viral cure for type 1 diabetes
Viruses can both cause and prevent autoimmune disease.
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Gene Worsens Artery Disease
UCLA/USC researchers have linked a variation of a gene called 5-lipoxygenase (5-LO) to an increased risk for atherosclerosis, or thickening of the arteries.
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"Mad Cow" Mechanism May Be Integral to Storing Memory
Scientists have discovered a new process for how memories might be stored, a finding that could help explain one of the least-understood activities of the brain.
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| 2003-12-12 |
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New method of identifying and isolating stem cells developed
The new animal model was successfully tested by isolating and characterizing skin stem cells.
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Chimp Genome Assembled
Draft Sequence Aligned With Human Genome
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| 2003-12-09 |
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Mouse model of human pancreatic cancer
Researchers at Dana-Farber Cancer Institute have created bioengineered mice that develop aggressive, fatal pancreatic cancer through the same genetic mishaps that cause the disease in humans.
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Novel strategy to help prevent transplant rejection
It is possible to help prevent organ rejection using a novel strategy that redirects the body's immune response instead of suppressing it.
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Biodegradable Gene Carrier
New Polymer Material that Delivers Genes into Cells
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| 2003-12-08 |
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Web-based Exhibit Marks the 25th Anniversary of the Home Pregnancy Test
NIH Scientists Pioneered Research into Reproductive Hormone Radioimmunoassay
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Yeast Model Yields Insights Into Parkinson’s Disease
Alpha-synuclein biology and Parkinson's Disaease
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Early Treatment of Blinding Eye Disease in Infants Can Prevent Severe Vision Loss
Clinical trial publishes new findings.
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| 2003-12-02 |
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RNA Interferes With Parkinson Gene
Researchers have created a mouse model of Parkinson disease using a technique called viral-mediated RNA interference (RNAi).
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VEGF-C Prevents Internal Drowning
Researchers identify a critical factor, vascular endothelial growth factor C (VEGF-C), which is required to develop and maintain the lymphatic system.
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Novel Protein Rations Iron
Study identifies a protein important in regulating iron stores in the body.
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Arthritic Clue
The study may help us to understand the causes and molecular mechanisms of some forms of human rheumatoid arthritis.
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Ecstasy Cools Down
The discovery may lead the way to counteracting the potentially lethal hyperthermia induced by this drug.
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Gender Benders
This research is a step closer to understanding how the Y chromosome gene Sry drives the development of testes.
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Biofilm Barrier
Research suggest that co-treatment, with an antibiotic and a compound that targets a specific glucan in the biofilm, might help to overcome antibiotic resistance.
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| 2003-12-01 |
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Gene may protect against heart disease rather than be harmful as previously thought
A genetic pathway whose activity was suspected to advance heart disease by increasing inflammation in the blood vessels and arteries feeding the heart may actually protect against it at least in laboratory mice.
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| 2003-11-25 |
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Genes Control Severity of Heart Failure, Study Finds
Researchers have discovered multiple stretches of DNA containing genes that modify the heart's pumping ability and survival with the disease.
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Gliomas’ “protein fingerprint”
Protein patterns of gliomas can be used to classify tumors and predict their aggressiveness.
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Scientists Report on Promising New Approaches to Induce Cancer Cell Suicide
The findings were presented at the International Conference on Molecular Targets and Cancer Therapeutics.
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DNA Used to Create Self-Assembling Nano Transistor
Breakthrough Proves Possible to Use Biology to Create Electronics
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Calcium Channels Control Coronary Artery Relaxation
Novel target for drugs to treat cardiovascular disease.
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Researchers Design and Build First Artificial Protein
Using sophisticated computer algorithms and standard desktop computers, HHMI researchers have designed and constructed a novel functional protein that is not found in nature.
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