| 2005-04-05 |
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HIV's Early Victims Revealed
Two papers, published online, shed crucial light on the earliest events in the human body after an HIV infection.
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| 2005-04-03 |
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BIOS - Biological Innovation for Open Society
is a new initiative to extend the metaphor and concepts of open source and distributive innovation to biotechnology and other forms of innovation in biology.
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| 2005-04-01 |
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Immunotherapy for Treatment of Melanoma
NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma
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Blocked Arteries in Brain - Aspirin Safer than Warfarin
For the first time, clinical trial shows that aspirin works as well as warfarin with fewer side effects for treating blocked arteries in the brain.
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| 2005-03-28 |
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Cat Allergies Be Gone
Novel Therapy Tested in Mice Could Chase Away Cat Allergies
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| 2005-03-25 |
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Avian Flu Vaccine Clinical Trial
NIAID, part of the NIH, recruits for safety clinical trial of a vaccine against H5N1 avian influenza.
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| 2005-03-22 |
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Visualizing Alzheimer Disease In The Living Brain
Japanese scientists describe a new technique for seeing amyloid plaques in living brains using commonly available brain-scanning technology, an important step toward developing an early diagnostic test for this devastating disease.
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RNAi Meets ALS
Two reports show that RNA interference might have therapeutic effects against amyotrophic lateral sclerosis (ALS).
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Predicting Stroke Risk In Sickle Cell Anemia
Study provides a predictive model that can identify sickle cell anemia (SCA) patients at risk of stroke with greater accuracy and faster than current methods allow, which may be useful as a prognostic test.
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Wnt Signals Two Ways To A Healthy Gut
The same signal that ensures that there are cells available to keep your intestine replenished also controls a cell type that is required to defend against bacterial infection.
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Tumour Warning In Blood Explained
Italian researchers have established a genetic mechanism for the long-sought-after link between cancer and blood clotting disorders.
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X Makes Its Mark
Genetic secrets of one of the most intriguing of human chromosomes: the X chromosome revealed.
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Vital Fertilization Factor Found
Researchers have, for the first time, identified a protein on sperm that is essential for fusion with eggs during fertilization.
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| 2005-03-20 |
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Hypermethylation of the RELN Gene May Play a Role in Schizophrenia
Epigenetic factors may explain the reduced expression of Reelin observed in the brains of schizophrenic patients.
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| 2005-03-18 |
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Studies Expand Understanding of X Chromosome
NIH-Supported Research Sheds New Light on the Role of Sex Chromosomes in Health and Disease
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Developments in Lung Cancer Treatment
Bevacizumab Combined With Chemotherapy Prolongs Survival for Some Patients with Advanced Lung Cancer
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| 2005-03-09 |
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Serotonin Transporter Gene Associated With Alcohol Consumption In Social Drinkers
Short allele of the 5HTT gene is correlated with increased alcohol intake
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| 2005-03-08 |
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Controlling Breast Cancer
Scientists have determined the shape of a receptor that is centrally involved in the development of hormone-sensitive breast cancers.
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Anti-Wrinkle Treatment
Report shows that features of premature aging can be reversed in cell culture.
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Genetic Factors In Heart Function
Two studies identify new genetic mutations underlying congenital heart malformations.
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New Insights Into Muscle Growth Regulation
New research has identified a way to regulate muscle growth in a way that should minimise the chance of unwelcome side effects, unlike current therapies.
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The Best Muscle Gene Therapy Of All?
Researchers have identified the optimal means of delivering therapeutic genes to muscle tissues with a single intravenous injection -- an approach that may prove useful for treating heart disease and muscular dystrophies.
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DNA Breaks Trigger Degeneration
Researchers have shown that patients with a neurodegenerative disease known as SCAN1 (spinocerebellar ataxia with axonal neuropathy-1) may have trouble repairing a specific type of defect in their DNA.
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Secrets Of HIV Unbound
Researchers describe the structure of the unbound form of gp120 derived from simian immunodeficiency virus (SIV).
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Stem Cell Puzzle Explained
Study shows how a stem cell can be committed to making a specific type of mature cell, while remaining undifferentiated until it is needed.
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| 2005-03-07 |
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Scientists Replicate Hepatitis C Virus in Laboratory
New In Vitro Model System Will Allow Study of Therapeutics and Virus Life Cycle
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Enzyme Shown To Help Protect Genomic Stability
Findings May Provide Insights into Aging and Cancer
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It's Not All Genetic: Common Epigenetic Problem Doubles Cancer Risk In Mice
Loss of Imprinting of Igf2 Alters Intestinal Maturation and Tumorigenesis
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Researchers Find New Technique To Identify Fetal Genetic Material
Global Gene Expression Analysis of the Living Human Fetus Using Cell-Free Messenger RNA in Amniotic Fluid
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Certain Genetic Test Helps Detect Mutations That May Be Missed By Conventional DNA Test
Researchers have identified a genetic test that when used with DNA testing would detect a higher number of genetic mutations in colorectal cancer patients
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Research Advances Quest For HIV-1 Vaccine
A new detailed structural analysis of the complex formed by an anti-HIV antibody called 4E10 and its specific target provides insight into why this particular antibody is so broadly effective
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New Medical Devices Can Cause New Immune Problems
Research findings could help with design of combination products that are not compromised by adverse host responses
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NCI Creates Gene Expression Database Of Normal Human Organ Tissue
Largest open-source database for normal tissue from human organs
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NHGRI Targets 12 More Organisms for Genome Sequencing
Strategic Mix Includes Marmoset, Skate and the vector of Chagas' disease
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| 2005-02-27 |
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Parasite Genome Sequenced
The genome of Entamoeba histolytica has been sequenced providing new insights into the physiology and evolution of this major human pathogen.
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Detecting Drug Cheats
New chip assay effectively detects prohibited drugs in the urine samples of athletes
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Blood Expression Profiles May Help Diagnose Schizophrenia
Accurate diagnoses of mental illnesses could soon be made by assessing gene expression profiles in blood.
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| 2005-02-22 |
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Mothers' Exposure To Air Pollutants Linked To Chromosome Damage In Babies
A new study of 60 newborns in New York City reveals that exposure of expectant mothers to combustion-related urban air pollution may alter the structure of babies' chromosomes while in the womb.
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Genotype Browser
Whole-genome patterns of common DNA variation in three human populations
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Test Could Improve Detection Of Prion Disease In Humans
A highly sensitive post-mortem test could help scientists more accurately determine if a person died of Creutzfeldt-Jakob disease (CJD).
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Advances In Uterine Leiomyoma Research: 2nd NIH International Congress
This conference will bring together researchers to foster an exchange of scientific information among members of the uterine leiomyoma (fibroids) research and health care communities.
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Reducing The Pain Of Stem Cell Therapy
Paper reports that stem cell transplantation treatment can also worsen a problem suffered by some spinal cord injury patients.
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Helping Stem Cells Maintain Their Humanity
Report of a new technique for human embryonic stem cell (hESC) culture that reduces the use of animal-derived compounds, making them potentially safer and more reliable for biomedical applications.
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Uncovering the Details of a Viral Secret Weapon
Data from the rigorous analysis of a variety of viral genomes may provide important new insights into the mechanisms of viral pathogenesis.
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Hair Growth Restores Hearing
A gene therapy approach to replace lost hair cells in the inner ear can improve hearing in deaf mammals.
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New Insights Into Muscle Growth Regulation
Research identifies a way to regulate muscle growth in a way that should minimise the chance of unwelcome side effects, unlike current therapies.
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Leptin Regulates Bone Remodelling
New research into bone structure and function shows how the hormone leptin plays a vital role in these processes, and could help our understanding of osteoporosis
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Researcher links schizophrenia, gene mutations
Altered genes cause receptors to become highly sensitive to their own dopamine, leading to psychosis
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Separating Chromosomes Improves Genetic Test Results
Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer
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Researchers Identify Enzyme That Activates Cancer Cell Growth And Invasion
PAR1 Is a Matrix Metalloprotease-1 Receptor that Promotes Invasion and Tumorigenesis of Breast Cancer Cells
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