To Mend A Failing Heart A method to create an artificial heart using the remains of an actual full-sized adult heart that has been stripped of all its cells, but then replanted with neonatal heart cells, may hold promise for its eventual use in transplant surgery.
Tethering HIV An antiviral molecule called a 'tetherin' that acts to inhibit HIV-1 particle release from cells is identified.
Suppressing A Leukaemia Suppressor The expression of genes that help to limit the growth of normal cells can sometimes be turned down in cancer, causing cells to divide uncontrollably - hence their branding as 'tumour suppressor' genes.
MicroRNAs That Reduce Metastasis Restoring the expression of certain microRNAs (miRNAs) that are lost as breast cancer starts to metastasize suppresses the spread of the cancer
First Sign Of Trouble Expression of a single stress response protein, even in the absence of 'danger' signals displayed by invading microbes or dying cells, triggers massive reorganization and activation of immune cells.
Gaining Entry Into The Brain Researchers have identified a protein used by aggressive immune cells seeking to breach the blood-brain barrier.
When Three Is Better Than Two People with Down's syndrome seem to be less susceptible to cancers - an observation that may at least partly derive from their having an extra copy of the chromosome responsible for the syndrome, chromosome 21.
A New Role For Nanog Nanog safeguards the pluripotent state of embryonic stem cells, resetting them if they start to differentiate when they shouldn't.