|
|
|
Cells that initiate human skin cancer are identified in Nature, and researchers demonstrate how targeting these cells with antibodies can slow the growth of melanomas.
Cancer stem cells have been isolated from a number of human tumours. Here Markus H. Frank and colleagues identify tumour-initiating cells in clinical human malignant melanomas. Tumours with ABCB5+ cells grow faster and spread quicker than those without. Preliminary evidence also suggests that these melanoma stem cells can be specifically targeted with antibodies targeted against ABCB5, which offers a potential therapeutic strategy against melanomas. CONTACT Markus H. Frank (Children's Hospital Boston and Brigham & Women's Hospital, Boston, MA, USA)
E-mail: mfrank@rics.bwh.harvard.edu (C) Nature press release.
Message posted by: Trevor M. D'Souza
|
|
Variants Associated with Pediatric Allergic Disorder
Mutations in PHF6 Found in T-Cell Leukemia
Genetic Risk Variant for Urinary Bladder Cancer
Antibody Has Therapeutic Effect on Mice with ALS
Regulating P53 Activity in Cancer Cells
Anti-RNA Therapy Counters Breast Cancer Spread
Mitochondrial DNA Diversity
The Power of RNA Sequencing
‘Pro-Ageing' Therapy for Cancer?
Niche Genetics Influence Leukaemia
Molecular Biology: Clinical Promise for RNA Interference
Chemoprevention Cocktail for Colon Cancer
more news ...
|