news archive genetic news - July 26, 2005

July 26, 2005

your information resource in human molecular genetics

-	Negotiating Responsibility: Case Studies Of Reproductive Decision-Making And Prenatal Genetic Testing In Families Facing Huntington Disease Three case studies are presented to further our understanding of how responsibility is negotiated in families when making decisions about genetic risk.
-	Men's Decision-Making About Predictive BRCA1/2 Testing: The Role Of Family This qualitative study explores the influences on male patients' genetic test decisions.
-	Evaluating Genetic Counseling: Client Expectations, Psychological Adjustment And Satisfaction With Service The role of counseling in facilitating the development of perceived personal control was a key contributor to a high sense of satisfaction in clients.
-	Racial-Ethnic Differences In Genetic Amniocentesis Uptake Individual health beliefs and knowledge play a greater role in genetic amniocentesis acceptance than do demographic factors such as race-ethnicity.
-	Synaptic Damage In Alzheimer Disease Study suggests a molecular mechanism that could shed light on how Alzheimer disease produces the dementia and memory loss that are its major symptoms.
-	Interfering With HIV Scientists have found a molecule that interferes with the formation of infectious Human immunodeficiency virus (HIV) particles.
-	Tickling Nerves Prevents Inflammation Stimulation of nicotinic acetylcholine receptors (nAChRs), which are found on both nerves and immune cells, can initiate a program that shuts down the inflammatory machinery of immune cells.
-	Susceptibility To Obesity And Diabetes Study reports a genetic variant associated with susceptibility to obesity and diabetes.
-	TACI Is Mutant In Common Variable Immunodeficiency And Iga Deficiency Two research studies present evidence for a new genetic factor underlying two human immunodeficiency syndromes.
-	Developing New Cellular Modules Scientists report the development of new mRNA-ribosome pairs that function orthogonally - in parallel with, but without affecting, endogenous ribosomal translation.
-	A Selective Gene-Repression Probe Researchers have identified a small-molecule inhibitor that may be a valuable tool for gene-repression studies.
-	DNA Adopts A New Fold Researchers report a new structure formed by a DNA sequence that is known to be important in cancer development.
-	Small Doses Go A Long Way Researchers have found a way of delivering small RNA molecules targeted against the hepatitis B virus at low doses.
-	A Structure Of Antidepressants' Binding Sites Scientists have now captured the crystal structure of a bacterial sodium chloride-dependent transporter, which moves leucine across membranes.
-	RBP4 Protein Contributes To Diabetes Researchers describe how a protein called RBP4, which is released by fat tissue, causes insulin resistance in mice.
-	Drug Shows Promise For Strengthening Hearts A new drug offers hope for warding off heart failure associated with Duchenne muscular dystrophy.
-	Cause Of Heart Valve Disease Identified Researchers have identified the genetic mutations that can produce a spectrum of cardiac abnormalities involving calcification of the aortic valve.