home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Genetic Variation In Hair, Eye, And Skin Pigmentation

 
  October, 31 2007 20:36
your information resource in human molecular genetics
 
     
Several new genetic associations for human hair, eye and skin pigmentation in individuals of European ancestry are reported online in Nature Genetics. Kari Stefansson and colleagues have conducted a genome-wide association study (GWAS) to identify genetic variation associated with human hair and eye pigmentation, as well as skin sensitivity to sun and freckling. The study included 2,986 Icelandic individuals in the initial genome-wide scan, followed by replication of significantly associated genetic loci in a second sample of 2,718 Icelandic and 1,214 Dutch individuals.

The authors identified 6 genetic loci associated with at least one of these pigmentation phenotypes, 4 of which have not been previously associated with pigmentation. The pigmentation characteristics of study participants were defined by self-assessment, and it is possible that more quantitative measures would identify further genetic associations. Most of the pigmentation variants identified in this study have, in previous studies, shown signals of positive selection in European populations.

Author contacts:

Kari Stefansson (deCODE Genetics, Reykjavik, Iceland)
E-mail: kstefans@decode.is

Daniel F. Gudbjartsson (deCODE Genetics, Reykjavik, Iceland)
E-mail: daniel.gudbjartsson@decode.is

Abstract available online.

(C) Nature Genetics press release.

 


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.