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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - January 15, 2009
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Thu, 15 Jan 2009 13:58:33 +0100

__________________________________________________________________________

   Bio-IT World Conference & Expo
   April 27-29, 2009, World Trade Center, Boston, MA

   Since its debut in 2002, the annual Bio-IT World Conference & Expo
   has established itself as the premier event showcasing the myriad
   applications of IT and informatics to biomedical research and the
   drug discovery enterprise.

   Detailed information about the event can be found at the event website:

   http://www.bio-itworldexpo.com
__________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - January 15, 2008 - http://hum-molgen.org


Genetic News
by T.M. D'Souza, S. Chandler, T. Dalaya, D. Forero, R. Kimmel,
K. Markey, J. Mill, R. Nemade, F.S. Zollmann
http://hum-molgen.org/NewsGen

- Cancer Stem Cells Leave Their Mark
    Inappropriate activation of a signalling pathway in intestinal stem
    cells causes them to become cancerous.
    http://hum-molgen.org/NewsGen/01-2009/000018.html

- Stem Cells and Disease Modelling
    Scientists have generated pluripotent stem cells from the skin cells
    of a patient with spinal muscular atrophy (SMA), and show that these
    cells can be used to model the specific pathology for inherited
    diseases.
    http://hum-molgen.org/NewsGen/01-2009/000017.html

- Cell-Cycle Restriction Helps Leukaemia Stem Cells Keep Going
    A protein that aids the survival of cancer-causing stem cells is
    described.
    http://hum-molgen.org/NewsGen/01-2009/000016.html

- Hijacked Pathway Contributes to Cancer Spread
    Lung cancer cells hijack immune system signalling pathways to
    stimulate metastasis.
    http://hum-molgen.org/NewsGen/01-2009/000015.html

- Arrestin' Insulin Resistance
    The protein beta-arrestin-2 helps ensure efficient insulin signalling
    by scaffolding key enzymes to the insulin receptor.
    http://hum-molgen.org/NewsGen/01-2009/000013.html

- Natural Killer Cells Never Forget
    A study reports that certain cells of the innate immune system can
    'remember' infectious agents - an ability previously only attributed
    to cells of the adaptive immune system.
    http://hum-molgen.org/NewsGen/01-2009/000011.html

- Breaking Through the Barrier
    A non-invasive method to deliver genes to the central nervous system
    in mice is reported online.
    http://hum-molgen.org/NewsGen/01-2009/000010.html

- Clearing Plaques In Blood Vessels In Alzheimer's Disease
    Scientists have uncovered the role of two critical proteins that
    negatively affect the clearance of amyloid beta in the brain, the
    accumulation of which is thought to lead to the development of
    Alzheimer's disease.
    http://hum-molgen.org/NewsGen/01-2009/000009.html

- Rotaviruses Stick to Sugars
    Sugar molecules on the surface of host cells are linked to all
    rotavirus infections.
    http://hum-molgen.org/NewsGen/01-2009/000008.html

- New Mechanism For Genetic Hair Loss
    Mutations that reduce the function of a small, previously unknown
    peptide cause a rare form of genetic hair loss.
    http://hum-molgen.org/NewsGen/01-2009/000007.html

- Common Mutation Underlying Epilepsy Identified
    A deletion on chromosome 15 is the most prevalent risk factor for
    common epilepsies identified to date.
    http://hum-molgen.org/NewsGen/01-2009/000006.html

- Female-Specific Genetic Risk Factor for Alzheimer's Disease
    A variant in a gene on the X chromosome is associated with increased
    risk of Alzheimer's disease specifically in women, according to a
    study published online.
    http://hum-molgen.org/NewsGen/01-2009/000005.html

- A Chip for Efficient Cell Fusion
    A device that enables efficient pairing and fusion of cells and
    allows easy observation of the process is presented in a study.
    http://hum-molgen.org/NewsGen/01-2009/000004.html

- Prions and Smell
    Study finds that Prions help us to distinguish odours.
    http://hum-molgen.org/NewsGen/01-2009/000003.html

- Higher Heart Rate May Predict Obesity
    Paper reports that a higher heart rate has been shown to predict
    obesity that manifests 20 years later.
    http://hum-molgen.org/NewsGen/01-2009/000002.html

- Increases in Melanoma
    Rising rates of melanoma cannot be attributed to better screening and
    detection of thin melanomas, according to a published paper.
    http://hum-molgen.org/NewsGen/01-2009/000001.html

- myExperiment.org: A repository of workflows in bioinformatics
    A new free platform is available for the organization and interchange
    of workflows in bioinformatics
    http://hum-molgen.org/NewsGen/12-2008/000013.html

- Contact Genetic News editors
    WWW: http://hum-molgen.org/editors.html
    E-mail: news@hum-molgen.org


Biomedical Positions
http://hum-molgen.org/positions/

- Write a position announcement
    http://hum-molgen.org/flyer/positions.pdf
    1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register
    2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login


DIAGnostics - Clinical Research (professional requests)
http://hum-molgen.org/clinical-research/

- Post diagnostic request / call for collaboration
    http://hum-molgen.org/diagnostic-posting or
    contact admin@hum-molgen.org


Biotechnical requests and sources
http://hum-molgen.org/biotechnology

- Post request or source
   http://hum-molgen.org/biotechnical-request-posting


Literature
http://hum-molgen.org/literature/


Events in bioscience and medicine
http://hum-molgen.org/meetings/

- The British Pharmaceutical Conference (Practice)
    Royal Pharmaceutical Society of Great Britain, Manchester Central
    Sunday 6 - Wednesday 9 September 2009
    http://hum-molgen.org/meetings/meetings/3750.html

- The British Pharmaceutical Conference (science)
    Royal Pharmaceutical Society of Great Britain, Manchester
    Sunday 6 - Wednesday 9 September 2009
    http://hum-molgen.org/meetings/meetings/3749.html

- GENOMIC-MEDICINE-2009
    American Society for Genomic Medicine (Stefan University), La Jolla,
    CA.
    November 20-November 22,2009.
    http://hum-molgen.org/meetings/meetings/3748.html

- DIA’s 1st Workshop on Pre-market Evaluation of Quality and
  Bioavailability
    Drug Information Association, Sci-Tech Centre, Mumbai, India.
    Feb 2 2009
    http://hum-molgen.org/meetings/meetings/3747.html

- Improving Solubility
    PharmaIQ, Thistle Marble Arch, London, U.K.
    2009-06-30 - 2009-07-01
    http://hum-molgen.org/meetings/meetings/3746.html

- Pharmaceutical & Biotech Patent Litigation Strategies
    PharmaIQ, London, U.K.
    2009-05-27/28
    http://hum-molgen.org/meetings/meetings/3745.html

- PEGS: the essential protein engineering summit
    Cambridge Healthtech Institute, Westin Copley Place, Boston,
    Massachusetts
    April 6-10, 2009
    http://hum-molgen.org/meetings/meetings/3744.html

- Beilstein Symposium on Glyco-Bioinformatics
    Beilstein-Institut, Potsdam
    October 4th - 8th, 2009
    http://hum-molgen.org/meetings/meetings/3743.html

- Experimental Standard Conditions of Enzyme Characterizations
    Beilstein-Institut, Ruedesheim, Germany
    13th - 16th Sept. 2009
    http://hum-molgen.org/meetings/meetings/3664.html

- 39th Annual Meeting of the American College of Clinical Pharmacology
    American College of Clinical Pharmacology, Baltimore Marriott
    Waterfront, Baltimore, MD
    September 12-14, 2010
    http://hum-molgen.org/meetings/meetings/3741.html

- 38th Annual Meeting of the American College of Clinical Pharmacology
    American College of Clinical Pharmacology, San Antonio, Texas
    September 13-15, 2009
    http://hum-molgen.org/meetings/meetings/3740.html

- Genetic Counselling in Practice
    European School of Genetic Medicine, EuroMediterranean University
    Centre of Ronzano, Bologna (Italy)
    6th-11th June 2009
    http://hum-molgen.org/meetings/courses/1853.html

-  Course in Medical Genetics
    European School of Genetic Medicine , Centro Residenziale
    Universitario , Bertinoro di Romagna
    26th April -2nd May 2009
    http://hum-molgen.org/meetings/courses/1852.html

- Selecting and Managing CROs
    The Center for Professional Innovation & Education, Malvern, PA
    March 31 - April 1, 2009
    http://hum-molgen.org/meetings/courses/1851.html

- Maximizing Global Patient Recruitment and Retention
    The Center for Professional Innovation & Education, Malvern, PA
    March 31 - April 1, 2009
    http://hum-molgen.org/meetings/courses/1850.html

- The Drug Development Process - From Discovery to Commercialization
    The Center for Professional Innovation & Education, Dublin, Ireland
    March 30 - April 1, 2009
    http://hum-molgen.org/meetings/courses/1849.html

- Effective Quality Assurance Auditing for FDA Regulated Industries
    The Center for Professional Innovation & Education, Dublin, Ireland
    March 30 & 31, 2009
    http://hum-molgen.org/meetings/courses/1848.html

- Detecting Fraud and Misconduct in Clinical Trials
    The Center for Professional Innovation & Education, Costa Mesa, CA
    March 30 & 31, 2009
    http://hum-molgen.org/meetings/courses/1847.html

- Preparation of FDA Submissions (INDs, BLAs, ANDAs, Post-Approval
   Supplements) and Communicating with the FDA
    The Center for Professional Innovation & Education, Malvern, PA
    March 26 & 27, 2009
    http://hum-molgen.org/meetings/courses/1846.html

- Root Cause Analysis for CAPA
    The Center for Professional Innovation & Education, Dublin, Ireland
    March 25 - 27, 2009
    http://hum-molgen.org/meetings/courses/1845.html

- Good Clinical Practices (GCPs)
    The Center for Professional Innovation & Education, Dublin, Ireland
    March 25 - 27, 2009
    http://hum-molgen.org/meetings/courses/1844.html

- Project Management for the Phase 3 and LCM (Life Cycle Management) of
   the Drug Development Process
    The Center for Professional Innovation & Education, Malvern, PA
    March 25 & 26, 2009
    http://hum-molgen.org/meetings/courses/1843.html

- Aseptic Processing in the Manufacture of Biotech and Pharmaceutical
   Products
    The Center for Professional Innovation & Education, Costa Mesa, CA
    March 23 & 24, 2009
    http://hum-molgen.org/meetings/courses/1842.html

- Project Management for Phase 1 & 2 Clinical Trials
    The Center for Professional Innovation & Education, Malvern, PA
    March 23 & 24, 2009
    http://hum-molgen.org/meetings/courses/1841.html

- Overview of FDA Regulatory Compliance For Medical Devices
    The Center for Professional Innovation & Education, Dublin, Ireland
    March 23 & 24, 2009
    http://hum-molgen.org/meetings/courses/1840.html

- Adverse Drug Events ­ Reporting & Regulatory Requirements
    The Center for Professional Innovation & Education, Dublin, Ireland
    March 23 & 24, 2009
    http://hum-molgen.org/meetings/courses/1839.html

- Understanding Regulatory & Clinical Information Systems During Product
   Development
    The Center for Professional Innovation & Education, Malvern, PA
    March 19 & 20, 2009
    http://hum-molgen.org/meetings/courses/1838.html

- Technical Writing for the Pharmaceutical, Medical Device, and Biotech
   Industries
    The Center for Professional Innovation & Education, Costa Mesa, CA
    March 18 - 20, 2009
    http://hum-molgen.org/meetings/courses/1837.html

- CMC Regulatory Compliance for Biopharmaceuticals and Biologics
    The Center for Professional Innovation & Education, Malvern, PA
    March 18 - 20, 2009
    http://hum-molgen.org/meetings/courses/1836.html

- Sterilization Procedures: Technology, Equipment and Validation
    The Center for Professional Innovation & Education, Malvern, PA
    March 18 & 19, 2009
    http://hum-molgen.org/meetings/courses/1835.html

- CMC/Quality Section of NDAs and INDs
    The Center for Professional Innovation & Education, Costa Mesa, CA
    March 16 & 17, 2009
    http://hum-molgen.org/meetings/courses/1834.html

- Validation of Computer Systems
    The Center for Professional Innovation & Education, Berlin, Germany
    March 16 & 17, 2009
    http://hum-molgen.org/meetings/courses/1833.html

- Clinical Trials Design for Medical Devices
    The Center for Professional Innovation & Education, Malvern, PA
    March 16 & 17, 2009
    http://hum-molgen.org/meetings/courses/1832.html

- Labeling and Labeling Controls in the Medical Devices Industry
    The Center for Professional Innovation & Education, Malvern, PA
    March 16 & 17, 2009
    http://hum-molgen.org/meetings/courses/1831.html

- Cleanroom Microbiology for the Non-Microbiologist
    The Center for Professional Innovation & Education, Malvern, PA
    March 16 & 17, 2009
    http://hum-molgen.org/meetings/courses/1830.html

- European Filing & Registration Procedures
    The Center for Professional Innovation & Education, Malvern, PA
    March 12 & 13, 2009
    http://hum-molgen.org/meetings/courses/1829.html

- Financial Fundamentals for Non-Financial Personnel - How Financial
   Issues Impact Business
    The Center for Professional Innovation & Education, Malvern, PA
    March 12 & 13, 2009
    http://hum-molgen.org/meetings/courses/1828.html

- The CTD/eCTD: Building the Marketing Application Throughout Clinical
   Development
    The Center for Professional Innovation & Education, Malvern, PA
    March 11 - 13, 2009
    http://hum-molgen.org/meetings/courses/1827.html

- The EU Clinical Trial Directive
    The Center for Professional Innovation & Education, Malvern, PA
    March 10 & 11, 2009
    http://hum-molgen.org/meetings/courses/1826.html

- Introduction to Molecular Biology Techniques ­ Applications in the
   Biotechnology and Pharmaceutical Industries
    The Center for Professional Innovation & Education, Malvern, PA
    March 9 - 11, 2009
    http://hum-molgen.org/meetings/courses/1825.html

- How to Prepare for a Systems-based Inspection ­ Understanding the
   FDA’s Risk-based Inspections Approach and Ensuring Compliance
    The Center for Professional Innovation & Education, Malvern, PA
    March 9 & 10, 2009
    http://hum-molgen.org/meetings/courses/1824.html

- How to Develop an Effective Complaint Handling and Post Market
   Surveillance Program for Drugs and Devices
    The Center for Professional Innovation & Education, Malvern, PA
    March 5 & 6, 2009
    http://hum-molgen.org/meetings/courses/1823.html

- Introduction to Statistical Analysis of Laboratory Data
    The Center for Professional Innovation & Education, Berlin, Germany
    March 5 & 6, 2009
    http://hum-molgen.org/meetings/courses/1822.html

- Stability Testing of Proteins, Peptides & Other Biomolecules
    The Center for Professional Innovation & Education, Malvern, PA
    March 4 & 5, 2009
    http://hum-molgen.org/meetings/courses/1821.html

- Calibration and Qualification of QC Laboratory Instrumentation
    The Center for Professional Innovation & Education, Malvern, PA
    March 4 & 5, 2009
    http://hum-molgen.org/meetings/courses/1820.html

- FDA Inspections: What To Expect And How To Prepare
    The Center for Professional Innovation & Education, Malvern, PA
    March 3 & 4, 2009
    http://hum-molgen.org/meetings/courses/1819.html

- Biostatistics for Non-Statisticians
    The Center for Professional Innovation & Education, Berlin, Germany
    March 2 - 4, 2009
    http://hum-molgen.org/meetings/courses/1818.html

- Analytical Method Validation for Pharmaceutical, Biopharmaceutical,
   and Biologics Quality Control
    The Center for Professional Innovation & Education, Malvern, PA
    March 2 & 3, 2009
    http://hum-molgen.org/meetings/courses/1817.html

- Stability Programs for Product Shelf Life ­ From Development to
   Approval
    The Center for Professional Innovation & Education, Malvern, PA
    March 2 & 3, 2009
    http://hum-molgen.org/meetings/courses/1816.html

- Combating Counterfeiting ­ Current Status of the New Technologies and
   Raising Public Awareness
    Royal Pharmaceutical Society of Great Britain, London
    18 March 2009
    http://hum-molgen.org/meetings/meetings/3739.html

- Embo Lecture Course in Mitochondrial Medicine:from genetics to
   biological mechanisms and beyond
    European School of Genetic Medicine, EuroMediterranean University
    Centre of Ronzano, Bologna (Italy)
    18th -22nd April 2009
    http://hum-molgen.org/meetings/courses/1815.html

- VetHealth Global 2009
    Delta Prince Edward, Charlottetown, Prince Edward Island
    October 6-8, 2009
    http://hum-molgen.org/meetings/meetings/3738.html

- ERA-EDTA ReGeNet Course in Genetic Epidemiology in Chronic Kidney
   Disease Research
    European School of Genetic Medicine , EuroMediterranean University
    Centre of Ronzano, Bologna (Italy)
    2009-03-30-2009-04-01
    http://hum-molgen.org/meetings/courses/1814.html

- Bioinformatics & Systems Biology for Molecular Biologists
    European School of Genetic Medicine, Bertinoro di Romagna
    22nd-26th March 2009
    http://hum-molgen.org/meetings/courses/1813.html

- International Workshop in Genetics, Medical Technologies & Health
   Policies
    European School of Genetic Medicine & Johns Hopkins University,
    Bologna SAIS Center, The Johns Hopkins University SAIS Bologna
    Center, Bologna (Italy)
    6th-8th March 2009
    http://hum-molgen.org/meetings/courses/1812.html

- Pharma Licensing Event PharmaVenue
    PharmaVenue, Mirasierra Suites Hotel Madrid (Spain)
    May 11-12 , 2009
    http://hum-molgen.org/meetings/meetings/3737.html

- DIA's 3rd Annual Conference on Drug Discovery and Clinical Development
   in India: Scientific, Regulatory, and Social Frontiers
    Drug Information Association, Renaissance Mumbai Hotel & Convention
    Centre, Mumbai, India.
    Feb 25 2009
    http://hum-molgen.org/meetings/meetings/3736.html

- Clinical Testing Submissions
    The Center for Professional Advancement, 90 Minute Accredited Online
    Training
    March 10, 2009 at 11:00 a.m. - 12:30 p.m. (EST)
    http://hum-molgen.org/meetings/courses/1811.html

- 8th Annual Biological Production Forum 2009
    Swissotel, Dusseldorf
    24th-26th June 2009
    http://hum-molgen.org/meetings/meetings/3735.html

- 2nd Bioinformatics Satellite Workshop on Stem Cell Data
    U Rostock, ; Helmholtz Institute for Biomedical Engineering,
    Pauwelsstrasse 20, 52074 Aachen
    2009-03-26
    http://hum-molgen.org/meetings/courses/1810.html

- Testing for Skin Irritation, Corrosion and Sensitization: Compliance
   with REACH and the 7th Amendment
    The Center for Professional Advancement, 90 Minute Accredited Online
    Training
    March 5, 2009 at 11:00 a.m. - 12:30 p.m. (EST)
    http://hum-molgen.org/meetings/courses/1809.html

- Molecular Mechanisms of Aging and Age-Related Diseases
    Abcam, Puerto Vallarta, Mexico
    March 3-6, 2009
    http://hum-molgen.org/meetings/meetings/3732.html

- Antigenic Variation  and Immune Evasion
    Fondation Mérieux, Les Pensières, Annecy. France
    2009-03-30/2009-04-01
    http://hum-molgen.org/meetings/meetings/3731.html

- BITS '09 - Sixth Annual Meeting of the Bioinformatics Italian Society
    University of Genova, Casa Paganini, Genova, Italy
    18-20 March 2009
    http://hum-molgen.org/meetings/meetings/3730.html

- Critical Limits, Monitoring and Corrective Actions­A HACCP Review
    The Center for Professional Advancement, 90 Minute Accredited Online
    Training
    March 12, 2009 at 11:00 a.m. - 12:30 p.m. (EST)
    http://hum-molgen.org/meetings/courses/1808.html

- Implementing GEP (Good Engineering Practices) in the Pharmaceutical,
   Bio-Pharmaceutical, and Medical Device Industries
    The Center for Professional Advancement, 90 Minute Accredited Online
    Training
    March 24, 2009 at 11:00 a.m. - 12:30 p.m. (EST)
    http://hum-molgen.org/meetings/courses/1807.html

- 18th International Workshop of the International Society for the Study
   of Vascular Anomalies
    de Duve Institute and Cliniques universitaires Saint-Luc, Universite
    catholique de Louvain, Brussels, BELGIUM
    21-24 April, 2010
    http://hum-molgen.org/meetings/meetings/3729.html

- From Functional Siloxanes to Performance Enhancing Applications
    The Center for Professional Advancement, 90 Minute Accredited Online
    Training
    April 14, 2009 at 11:00 a.m. - 12:30 p.m. (EST)
    http://hum-molgen.org/meetings/courses/1806.html

- Effective Clinical Data Acceptance Testing
    The Center for Professional Advancement, 90 Minute Accredited Online
    Training
    February 19, 2009 at 11:00 a.m. - 12:30 p.m. (EST)
    http://hum-molgen.org/meetings/courses/1805.html

- Lyophilization 101: Scale-Up, Cycle Transfer, and Sonic Water Vapor
   Flow
    The Center for Professional Advancement, 90 Minute Accredited Online
    Training
    February 3, 2009 at 11:00 a.m. - 12:30 p.m. (EST)
    http://hum-molgen.org/meetings/courses/1804.html

- Joint EMBL/Genomatix Workshop on mRNA-Seq and ChIP-Seq Comprehensive
   Methods for Next Generation Sequencing Data Analysis
    EMBL, Heidelberg, Germany
    09 - 10 March 2009
    http://hum-molgen.org/meetings/courses/1803.html

- Post event (free)
   http://hum-molgen.de/cgi-bin/meetings.pl?login


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http://hum-molgen.org/companies/


Mailing List Administration (Join or leave the list)
http://hum-molgen.org/subscribe-na/


Feedback
contact admin@hum-molgen.org


Advertise at HUM-MOLGEN
http://hum-molgen.org/flyer/advertise.pdf
contact FS Zollmann (dialogue@hum-molgen.org)

__________________________________________________________________________

   Bio-IT World Conference & Expo
   April 27-29, 2009, World Trade Center, Boston, MA

   http://www.bio-itworldexpo.com

   Since its debut in 2002, the annual Bio-IT World Conference & Expo
   has established itself as the premier event showcasing the myriad
   applications of IT and informatics to biomedical research and the
   drug discovery enterprise. The 2009 program will feature best practice
   case studies and joint partner presentations relevant to the
   technologies, research, and regulatory issues of life science,
   pharmaceutical, clinical and IT professionals.

   This year's event features keynote presentations by Chris Dagdigian,
   Founding Partner and Director of Technology, BioTeam, Inc.;
   Clifford Reid, Ph.D., Chief Executive Officer, Complete Genomics, Inc.;
   and Eric E. Schadt, Ph.D., Executive Scientific Director, Genetics,
   Rosetta Inpharmatics/Merck Research Labs.
   Spanning three days, the meeting includes six concurrent conference
   tracks dedicated to IT Infrastructure & Operations; Informatics for
   Genomic Medicine; Predictive and in silico 
Science; Computational Chemistry;
   Clinical and Medical Informatics; and eHealth Solutions.

   Detailed information about the event can be found at the event website:

   http://www.bio-itworldexpo.com

__________________________________________________________________________

--
| INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
| HUM-MOLGEN - http://hum-molgen.org
| (C) 1994-2009



   
 
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