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SARS Attacking the Ribosome
A double attack by the SARS virus on host cell protein synthesis is shown in a study published online.
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Heartbeat Awareness
The neural pathway by which we feel stimuli originating inside our bodies -- such as our heartbeat -- is illuminated by studying an unusual patient with unique patterns of brain damage.
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A Notch in Lung Arteries
The common signaling molecule Notch has a role in pulmonary arterial hypertension, often caused by insufficient oxygen reaching the lungs, as reported in a study.
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Layered Immunologic Memory
Distinct populations of antibody-producing memory immune cells arise due to vaccination.
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Possible Multiple Sclerosis Biomarker
Small molecules of RNA are positively associated with disease relapses in multiple sclerosis (MS) in patients according to a report published online.
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Age-Related Sperm Mutations Associated with Testicular Tumor
A rare type of benign testicular tumor is associated with genetic mutations arising from paternal age-effect mutations, which are inherited from fathers that are older than the population mean.
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A Genetic Region Implicated in Schizophrenia
Duplications of a given DNA sequence on chromosome 16 are associated with schizophrenia.
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CRLF2 Defects in Down Syndrome-Associated Leukemia
A chromosomal alteration that fuses the P2RY8 and CRLF2 genes is found in individuals with B-progenitor acute lymphoblastic leukemia (ALL) and ALL associated with Down syndrome (DS).
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Variants Associated with Systemic Lupus Erythematosus
Twelve new genetic variants are associated with increased risk of systemic lupus erythematosus (SLE), according to 2 independent studies published online.
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Ribosome Reactions
Two studies discuss new fundamental properties of the ribosome as well as new ways to manipulate the ribosomal machinery.
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Intravital Imaging Reveals Regulation of Metastasis
Activation of a specific intracellular signalling cascade determines whether cancer cells spread as single cells or as a collective unit, and whether they invade via the lymph system or blood.
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Stem Cells Help Study of Infertility Genes
Researchers have tracked and isolated germ cells derived from human embryonic stem cells and studied which genes are involved in their formation.
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Synapse, So What?
Study shows that certain neurons can exert their inhibitory effects without using the specialized intercellular junctions.
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Cancer Link to Microenvironment
A key signalling pathway that operates in mammary gland connective tissue cells helps to suppress the development of mammary tumours.
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Signalling Pathway Link to Cancer
The NF-kappaB signalling pathway has a vital role in certain cancers
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Repairing Memory after a Sleepless Night
The cognitive deficits caused by sleep deprivation may be reversible by reducing the concentration of a specific enzyme in the hippocampus of the brain.
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