news archive genetic news - January 4, 2007

January 4, 2007

your information resource in human molecular genetics

-	Ectopic Expression Of Glucagon-Like Peptide 1 For Gene Therapy Of Type II Diabetes Study results demonstrate the feasibility of gene therapy for type II diabetes using GLP-1 expression vectors.
-	Gene Therapy In Wound Healing: Present Status And Future Directions Article aims to review the research on gene therapy in wound healing and possible future directions in this exciting field.
-	Development Of A Novel Systemic Gene Delivery System For Cancer Therapy With A Tumor-Specific Cleavable PEG-Lipid Multifunctional Envelope-type Nano Device (MEND) modified with PPD is a promising device, which has the potential to make in vivo cancer gene therapy achievable.
-	New Streptococcal Virulence Factors Degradation of host glycogen is an important factor in bacterial pathogenesis.
-	Tolerating The Gut New research reveals why the immune system remains in check and does not attack gut tissues despite being full of bacteria.
-	Genetic Risk Factor For Crohn Disease Found A variant of a protein that normally promotes the digestion and clearance of bacteria by cells is associated with elevated risk of Crohn disease.
-	New Breast Cancer Susceptibility Gene Identified Individuals with mutations in a gene called PALB2 have more than twice the normal risk of breast cancer.
-	New Genetic Cause Of An Immunodeficiency Syndrome Found A gene called HAX1 is mutated in some individuals with an immunodeficiency syndrome known as severe congenital neutropenia (SCN).
-	Activating Drug Discovery For Gaucher Disease Scientists have identified a new structural form of the protein that is mutated in Gaucher disease.
-	Beefing Up Resistance To Mad Cow Disease A team of American and Japanese scientists has created cows that lack the protein responsible for mad cow disease.
-	Neurons Group Abstract Movement Scientists describe neurons in the lateral prefrontal cortex that become active before certain categories of movement.
-	Progeria Mutation Sheds Light On Normal Ageing Researchers provide firm evidence that specifically DNA damage contributes to ageing.
-	Starve The Tumour, Sabotage The Blood Supply A new drug that shrinks tumours by sabotaging their blood supply may work against cancers that have become resistant to standard anti-angiogenic therapies.
-	Microbial Component To Obesity The microbes living in our guts may influence how prone we are to obesity.