news archive genetic news - May 31, 2005

May 31, 2005

your information resource in human molecular genetics

-	Hydrolethalus Syndrome Is Caused By A Missense Mutation In A Novel Gene HYLS1 The authors identified an HLS associated mutation in the HYLS1 gene.
-	Novel Modifier Loci Of Aganglionosis In Hirschsprung Disease Identified Studies in HSCR families have identified RET-dependent modifiers for short-segment HSCR (S-HSCR).
-	A Noisy Basis For Dyslexia Dyslexic children are much worse than non-dyslexic children at seeing visual signals through noise.
-	New Strategy Makes Proteins A Better Drug Target Findings promise to considerably simplify the study of protein kinases.
-	Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice The authors report a genetic flaw that markedly reduced the intracellular expression of the high mobility group A1 (HMGA1).
-	Stat3 Is Required For ALK-Mediated Lymphomagenesis Stat3 provides a possible therapeutic target.
-	Stiff Handling Of Genes The efficacy of materials for carrying genes into cells may be determined by their stiffness.
-	Diverse Patterns Of Somatic Mutations In Human Breast Cancer Identified A previously hidden diversity of mutational processes may exist in breast cancer.
-	A New Mechanism Behind Atherosclerosis Abnormal metabolism in arterial walls can cause atherosclerosis.
-	Testicular Cancer Gene Identified Scientists identify a gene that causes testicular cancer in mice.