home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Diverse Patterns Of Somatic Mutations In Human Breast Cancer Identified

  May, 31 2005 10:49
your information resource in human molecular genetics
Paper title: A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

Authors: Philip Stephens et al.

Journal: Nature Genetics, June 2005.

The coding sequences of 518 protein kinases in 25 breast cancers were examined. In many tumors, no somatic mutations were detected. But a few had numerous somatic mutations with distinctive patterns indicative of either a mutator phenotype or a past exposure.

The results indicate that a previously hidden diversity of mutational processes exists in breast cancer.

Author contact:

Michael R Stratton
The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.

E-mail: mrs@sanger.ac.uk

Also available online.

(C) Nature Genetics.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2018 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.