Specific intervention by gene therapy is a possible alternative and complementary strategy for the treatment of breast cancer. Several gene therapy approaches for carcinoma of the breast have been developed, that fall into into six broad categories: (1) mutation compensation, (2) molecular chemotherapy, (3) proapoptotic gene therapy, (4) antiangiogenic gene therapy, (5) genetic immunopotentiation, and (6) genetic modulation of resistance/sensitivity, and are described in this review, published in Cancer Gene Therapy (by M. A. Stoff-Khalili1, P. Dall, and D. T. Curiel; Vol. 13, pp. 633-647, 2006).
Dr. D. T. Curiel, Division of Human Gene Therapy, Gene Therapy Center, University of Alabama at Birmingham, 901 19th Street South, BMR2 502, Birmingham, AL 35294, USA.
Free Full Text Article available online.
(C) Cancer Gene Therapy.
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