Specific intervention by gene therapy is a possible alternative and complementary strategy for the treatment of breast cancer. Several gene therapy approaches for carcinoma of the breast have been developed, that fall into into six broad categories: (1) mutation compensation, (2) molecular chemotherapy, (3) proapoptotic gene therapy, (4) antiangiogenic gene therapy, (5) genetic immunopotentiation, and (6) genetic modulation of resistance/sensitivity, and are described in this review, published in Cancer Gene Therapy (by M. A. Stoff-Khalili1, P. Dall, and D. T. Curiel; Vol. 13, pp. 633-647, 2006).
Dr. D. T. Curiel, Division of Human Gene Therapy, Gene Therapy Center, University of Alabama at Birmingham, 901 19th Street South, BMR2 502, Birmingham, AL 35294, USA.
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(C) Cancer Gene Therapy.
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