home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Urine Test for Kidney Disease

 
  April, 23 2009 8:15
your information resource in human molecular genetics
 
     

Scientists have developed a new test for detecting kidney disease, reports a paper published online in Kidney International. The technique will allow researchers and clinicians to identify kidney disease or injury within 15 minutes of testing in both rats and humans.

The test, developed by Vishal Vaidya and colleagues, measures the urinary biomarker of a molecule known as Kim-1, which has been shown to better indicate a range of renal conditions over other conventional biomarkers such as blood urea nitrogen, serum creatinine, and urinary enzymes. The new assay displays visual indicators in minutes, which is a significant improvement from older analyses which require a large analyzer and take several hours.

The kidney is highly susceptible to injury due to various disease states, a wide range of drugs, environmental pollutants, and other conditions. The incidence of kidney injury is steadily increasing across the population and contributes to high mortality and increasing numbers of individuals with end-stage kidney disease. This assay has potential to diagnose kidney disease quickly and early enough to provide timely therapeutic intervention, and could also be used in the future to safely screen for agents which are potentially nephrotoxic in preclinical and clinical settings.

Author contact:

Vishal S. Vaidya (Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA)
E-mail: vvaidya@partners.org

Abstract available online.

 (C) Kidney International press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.