Gene Elements That Control Cell Evolution Three large studies unravel the network underlying the genetic elements that control how cells transform and evolve from precursors to mature cells.
Cancer Genomics Hits Its Stride A look back at the achievements of cancer genomics, and forward to the prospect that the complete DNA sequencing of large numbers of cancers will help us move towards a deeper understanding of how to treat cancers.
New Approach to Cancer Treatment A new drug that shows robust anti-tumour activity in a preclinical mouse model of cancer, is reported.
Rethinking Tumour Spread Scientist proposes a drastic change in how we view metastatic spread, which has important implications for the treatment of patients with cancer.
Pluripotency by Piggybac Researchers have developed a method to create induced pluripotent stem cells (iPSCs) with an unmodified genome.
Finding Footprints in the Genome A method for measuring in vivo protein occupancy in the entire yeast genome is presented in a study.
Softening Bone A molecular mechanism that promotes bone destruction could be harnessed to combat osteoporosis.
A New Treatment for Arrhythmia A drug currently available in the clinic could be used to treat patients with an inherited form of cardiac arrhythmia.
Unexpected Tumour Growth? Blood vessel inhibitors have been pursued as anticancer agents, but in low doses they may actually promote blood-vessel formation and tumour growth in mice.
A Secret Doorway into the Brain Scientists have identified how immune cells bypass the blood-brain barrier to enter the brain, which in turn allows other immune cells to enter the brain and cause disease.
Risk Factors for Cardiovascular Health Several genetic variants that predispose individuals to sudden cardiac death have been identified in two studies published online.
Stem Cells Generate Intestine Cultured intestinal stem cells can be coaxed to produce the many different cell types that make up the intestinal epithelium.
Peek-A-Boo Perception From a young age, children with autism have an altered perception of biological motion - an ability that assists interaction with other living beings and is linked to social understanding.