home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Cancer Genomics Hits Its Stride

 
  April, 23 2009 7:45
your information resource in human molecular genetics
 
     

In a review in Nature, Michael Stratton and colleagues look back at the achievements of cancer genomics, and forward to the prospect that the complete DNA sequencing of large numbers of cancers will help us move towards a deeper understanding of how to treat cancers.

Since the discovery in 1982 of the link between HRAS gene mutations and bladder cancer, many more abnormal genes have been identified in cancer patients. As a result much has been learned about the development of cancer, but with so many distinct cancer and tissue types there is much more to be learned, argue the authors.

Genomicists aim to provide a comprehensive catalogue of acquired mutations in at least 50 classes of cancer, including those with the highest global incidence and mortality. This proposal has generated controversy reminiscent of the debate before sequencing of the human genome almost 20 years ago. However, the information gained is likely to have a huge impact on drug development and clinical practice, seeing a move towards an era of genome-related individualized therapeutic decision making. "The discussion is therefore not about whether to do the experiment, but when and how" say the authors.

CONTACT

Michael Stratton (Wellcome Trust Sanger Institute, Hinxton, UK)
E-mail: don@sanger.ac.uk

(C) Nature press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.