your information resource in human molecular genetics
2008-01-24
Sleep Provides A Window Into Memory Patterns of brain activity while awake can shape the formation of their neuron connections during sleep.
A Stem Cell-Based Therapy To Treat Muscular Dystrophy A new way to manipulate embryonic stem cells (ESCs) in mice offers hope for an eventual cell-based therapy to treat muscular dystrophies, suggests a paper online.
To Mend A Failing Heart A method to create an artificial heart using the remains of an actual full-sized adult heart that has been stripped of all its cells, but then replanted with neonatal heart cells, may hold promise for its eventual use in transplant surgery.
Genetics Of Height And Bone Disease Variants on a genetic locus related to osteoarthritis also affect the height of an individual, according to research.
Receptor Signalling In Pairs Scientists have discovered new information about the way that small molecules cause cell signalling.
Transmitting HIV Through T Cell Nanotubes Membrane nanotubes formed by contact between immune T-cells significantly increase transmission efficiency of HIV between infected and uninfected cells.
RNA And Tumour Suppression Researchers identify a candidate tumour suppressor gene for the deletions on chromosome 5q that are associated with certain blood-cell-production diseases.
Tethering HIV An antiviral molecule called a 'tetherin' that acts to inhibit HIV-1 particle release from cells is identified.
Suppressing A Leukaemia Suppressor The expression of genes that help to limit the growth of normal cells can sometimes be turned down in cancer, causing cells to divide uncontrollably - hence their branding as 'tumour suppressor' genes.
MicroRNAs That Reduce Metastasis Restoring the expression of certain microRNAs (miRNAs) that are lost as breast cancer starts to metastasize suppresses the spread of the cancer
The Protective Effects of Brain Damage Combat veterans with certain types of brain damage are less likely to develop post-traumatic stress disorder (PTSD).
A Pathway Controlling Body Temperature Scientists have identified neurons that relay temperature information from sensory fibres in the spinal cord to the thermoregulatory control centre in the brain.
Walking After Spinal Rewiring Rewiring of nerve fibres in the spinal cord helps mice to regain the ability to walk after injury.
First Sign Of Trouble Expression of a single stress response protein, even in the absence of 'danger' signals displayed by invading microbes or dying cells, triggers massive reorganization and activation of immune cells.
Gaining Entry Into The Brain Researchers have identified a protein used by aggressive immune cells seeking to breach the blood-brain barrier.
Genetic Risk Factor For ALS Scientists have identified a variant in the gene DPP6 that increases susceptibility to amyotrophic lateral sclerosis (ALS).
Breast Cancer Goes NUMB A protein called NUMB has a crucial role in keeping breast cancer at bay.
When Three Is Better Than Two People with Down's syndrome seem to be less susceptible to cancers - an observation that may at least partly derive from their having an extra copy of the chromosome responsible for the syndrome, chromosome 21.
A New Role For Nanog Nanog safeguards the pluripotent state of embryonic stem cells, resetting them if they start to differentiate when they shouldn't.
Looking For Cancer In All The Right Places Viable tumour-derived epithelial cells (also known as circulating tumour cells or CTCs) have been identified in the blood of cancer patients.
Brain Cells Are Smarter Than You Think Individual brain cells can make a bigger contribution to behaviour and are capable of more computations than previously thought.