HUM-MOLGEN archive: HUM-MOLGEN News Alert

__________________________________________________________________________ 2nd Modern Drug Discovery and Development Summit (M3D) December 4-6, 2006 - Philadelphia, PA - Learn from over 250 expert speakers - Attend 11 full conferences at 1 venue - View numerous cutting edge posters - Network with a few thousand of your peers - Establish key business ties with executives and scientists dedicated to drug discovery Visit http://gtcbio.com/confpage.asp?cid=8 for more information __________________________________________________________________________ INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS HUM-MOLGEN News Alert - October 13, 2006 - http://hum-molgen.org Genetic News by T.M. D'Souza, S. Chandler, T. Dalaya, K. Markey, J. Mill, La Merie S.L, R. Nemade, D. Sharma, F.S. Zollmann http://hum-molgen.org/NewsGen - Detecting Disease-Causing Mutations in the Human Genome by Haplotype Matching The authors describe a new strategy for detecting mutations that is based on comparing affected haplotypes with closely matched control sequences from healthy individuals, rather than with the human reference genome. http://hum-molgen.org/NewsGen/10-2006/msg17.html - PLA2G6 Mutation Underlies Infantile Neuroaxonal Dystrophy The study findings highlight a role of phospholipase in neurodegenerative disorders. http://hum-molgen.org/NewsGen/10-2006/msg16.html - A Novel Mutation in FGFR3 Causes Camptodactyly, Tall Stature, and Hearing Loss (CATSHL) Syndrome Abnormal FGFR3 signaling can cause human anomalies by promoting as well as inhibiting endochondral bone growth. http://hum-molgen.org/NewsGen/10-2006/msg15.html - Systems Biology Tackles The Mechanisms Of Cancer Potential novel targets for anti-cancer therapy are revealed. http://hum-molgen.org/NewsGen/10-2006/msg14.html - Itching And Scratching Dust mites produce an allergen that disrupts the skin's ability to act as a barrier to other allergens and environmental irritants. http://hum-molgen.org/NewsGen/10-2006/msg13.html - Recommendations Help Identify Patients Suitable For NSAID Treatment Recommendations should help physicians to identify quickly whether or not a patient is suitable for treatment with nonsteroidal anti-inflammatory drugs (NSAIDs). http://hum-molgen.org/NewsGen/10-2006/msg12.html - Focus On Childhood Developmental Disorders A special focus issue on childhood developmental disorders, including specific language impairment and dyslexia, autism, and the mental retardation syndrome fragile X, is presented. http://hum-molgen.org/NewsGen/10-2006/msg11.html - New Strategy For Controlling Inflammation A previously unknown method of terminating immune responses is reported. http://hum-molgen.org/NewsGen/10-2006/msg10.html - New Breast Cancer Susceptibility Gene Identified Women with mutations in a gene called BRIP1 have twice the normal risk of breast cancer. http://hum-molgen.org/NewsGen/10-2006/msg09.html - One Step Toward More Efficient Cloning A one-step somatic cell nuclear transfer procedure using a differentiated cell as a nuclear donor is reported for the first time. http://hum-molgen.org/NewsGen/10-2006/msg08.html - Controlling The Insulin-Degrading Enzyme May Relieve Alzheimer's Disease The structure of an enzyme that degrades insulin and amyloid-beta suggests a possible way to design drugs that combat the abnormal levels of these proteins in sufferers of diabetes or Alzheimer's disease. http://hum-molgen.org/NewsGen/10-2006/msg07.html - Drug Target For Obesity? A molecule that makes mammals feel full up has been identified. http://hum-molgen.org/NewsGen/10-2006/msg06.html - Potential Cure for Type 1 Diabetes in Islet Transplantation Clinical Trial Shows Islet Transplantation is a Promising Procedure For Certain Patients with Severe Type 1 Diabetes http://hum-molgen.org/NewsGen/10-2006/msg05.html - H9N2 Avian Flu Vaccine Paired with Adjuvant Provokes Strong Human Immune Response Clinical trial reports that when combined with an adjuvant, low doses of an experimental vaccine against a strain of avian influenza (H9N2) provoked a strong antibody response in human volunteers. http://hum-molgen.org/NewsGen/10-2006/msg04.html - Another Gene Implicated in Cleft Lip and Palate Underexpression of SUMO1 can cause the world's most common birth defect, cleft lip and palate. http://hum-molgen.org/NewsGen/10-2006/msg03.html - Connectivity Map Using gene-expression signatures to connect small molecules, genes, and disease http://hum-molgen.org/NewsGen/10-2006/msg02.html - Jumping gene could provide non-viral alternative for gene therapy piggyBac is a flexible and highly active transposon as compared to Sleeping Beauty, Tol2, and Mos1 in mammalian cells http://hum-molgen.org/NewsGen/10-2006/msg01.html - Contact Genetic News editors WWW: http://hum-molgen.org/editors.html E-mail: news@hum-molgen.org DIAGnostics - Clinical Research (professional requests) http://hum-molgen.org/clinical-research/ - Post diagnostic request / call for collaboration http://hum-molgen.org/diagnostic-posting or contact admin@hum-molgen.org Biomedical Positions http://hum-molgen.org/positions/ - Genetics: Principal Investigator Pfizer Inc, Groton, 06340, United States of America http://hum-molgen.org/positions/non_academic_positions/1696.html - Write a position announcement http://hum-molgen.org/flyer/positions.pdf 1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register 2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login Biotechnical requests and sources http://hum-molgen.org/biotechnology - Post request or source http://hum-molgen.org/biotechnical-request-posting Literature http://hum-molgen.org/literature/ Events in bioscience and medicine http://hum-molgen.org/meetings/ - Post event (free) http://hum-molgen.de/cgi-bin/meetings.pl?login Registry of Biomedical Companies (1346 active entries) http://hum-molgen.org/companies/ Mailing List Administration (Join or leave the list) http://hum-molgen.org/subscribe-na/ Feedback contact admin@hum-molgen.org Advertise at HUM-MOLGEN http://hum-molgen.org/flyer/advertise.pdf contact FS Zollmann (dialogue@hum-molgen.org) __________________________________________________________________________ 2nd Modern Drug Discovery and Development Summit (M3D) December 4-6, 2006 - Philadelphia, PA - Learn from over 250 expert speakers - Attend 11 full conferences at 1 venue - View numerous cutting edge posters - Network with a few thousand of your peers - Establish key business ties with executives and scientists dedicated to drug discovery Visit http://gtcbio.com/confpage.asp?cid=8 for more information __________________________________________________________________________ -- | INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS | HUM-MOLGEN - http://hum-molgen.org | (C) 1994-2006