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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - September 21, 2005
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Wed, 21 Sep 2005 13:58:04 +0200

__________________________________________________________________________

   Discovery on Target 2005

   Target Discovery and Target Validation Strategies
   October 18-21, 2005 - Boston, MA

   http://hum-molgen.org/promotion-DoT
__________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - September 21, 2005 - http://hum-molgen.org


DIAGnostics - Clinical Research (professional requests)
http://hum-molgen.org/clinical-research/

- Mevalonate Kinase Deficiency Research
   http://hum-molgen.org/bb/Forum2/HTML/000183.html

- Post diagnostic request / call for collaboration
   http://hum-molgen.org/diagnostic-posting or
   contact admin@hum-molgen.org


Genetic News
by T.M. D'Souza, T. Dalaya, J. Mill, R. Nemade, D. Sharma, F.S. Zollmann
http://hum-molgen.org/NewsGen

- Connotea Wins Award For Publishing Innovation
   Connotea, a free online reference management service for scientists,
   developed by Nature Publishing Group, has won the Association of
   Learned and Professional Society Publishers (ALPSP) Award for
   Publishing Innovation.
   http://hum-molgen.org/NewsGen/09-2005/msg51.html

- An Assessment of Risk Understanding in Hispanic Genetic Counseling
  Patients
   This study sought to identify if differences existed in risk
   comprehension and risk format understanding between genetic counseling
   patients of Hispanic and Caucasian ethnicity.
   http://hum-molgen.org/NewsGen/09-2005/msg50.html

- Psychosocial Issues That Face Patients With Charcot-Marie-Tooth
  Disease: The Role of Genetic Counseling
   This study identifies and explores life issues that individuals with
   Charcot-Marie-Tooth Disease (CMT) may face.
   http://hum-molgen.org/NewsGen/09-2005/msg48.html

- Women.s Attitudes Toward Testing for Fragile X Carrier Status: A
  Qualitative Analysis
   Findings have significant implications for genetic counseling as well
   as for population screening.
   http://hum-molgen.org/NewsGen/09-2005/msg47.html

- Educating Genetic Counselors in Australia: Developing an International
  Perspective
   This paper highlights the Australian experience of genetic counselor
   education and the history of the profession.
   http://hum-molgen.org/NewsGen/09-2005/msg46.html

- Smoking Delays Response To Eye Disease Treatments
   Response to treatment for episcleritis and scleritis is likely to be
   delayed by at least 4 weeks if patients are smokers.
   http://hum-molgen.org/NewsGen/09-2005/msg44.html

- Scientists Confirm That Smoking Causes Blindness
   Smoking greatly increases your chance of developing age-related
   macular degeneration (AMD), which leads to severe and irreversible
   sight-loss.
   http://hum-molgen.org/NewsGen/09-2005/msg43.html

- Nitrite Gives A Signal
   Paper reports that nitrite -- a common additive in foods such as hot
   dogs -- is a built-in signaling molecule that regulates multiple
   biochemical pathways.
   http://hum-molgen.org/NewsGen/09-2005/msg42.html

- Genome Mining Reveals New Natural Products
   Researchers have discovered a new microbial natural product by a
   technique called "genome mining."
   http://hum-molgen.org/NewsGen/09-2005/msg41.html

- A Forceful Finding About Atherosclerosis
   Scientists show that three proteins, which are expressed in vessel
   endothelial cells, are required for detecting mechanical stress on the
   vessel walls.
   http://hum-molgen.org/NewsGen/09-2005/msg40.html

- An Outside-In View Of Psoriasis
   Researchers have found that cells in human psoriatic lesions have
   decreased expression of the gene JUNB.
   http://hum-molgen.org/NewsGen/09-2005/msg39.html

- The Spiniest Aspect Of Amyloid Formation
   Scientists report how amyloid fibrils, protein structures found in a
   number of neurodegenerative disorders, can "zip up" without losing
   their ability to function properly.
   http://hum-molgen.org/NewsGen/09-2005/msg38.html

- On The Origin And Size Of Infectious Prions
   Malformed prion proteins appear to be responsible for transmissible
   spongiform encephalopathies such as Creutzfeldt-Jakob disease.
   http://hum-molgen.org/NewsGen/09-2005/msg37.html

- Opposite Effects, But One Target
   Scientists have identified a link between two major pathways that
   regulate blood glucose levels.
   http://hum-molgen.org/NewsGen/09-2005/msg36.html

- Unusual RNAs Linked To Chronic Leukemia, May Help Treat It
   miR-15 and miR-16 induce apoptosis by targeting BCL2.
   http://hum-molgen.org/NewsGen/09-2005/msg35.html

- Most Embryos Produced During IVF do not Result in Live Births
   High rates of embryo wastage with use of assisted reproductive
   technology
   http://hum-molgen.org/NewsGen/09-2005/msg34.html

- Adult Human Neural Stem Cell Therapy Successful In Treating Spinal
   Cord Injury
   Human neural stem cells differentiate and promote locomotor recovery
   in spinal cord-injured mice
   http://hum-molgen.org/NewsGen/09-2005/msg33.html

- Superlattice Nanobelts
   Nanohelix Structure Provides New Building Block for Nanoscale
   Piezoelectric Devices
   http://hum-molgen.org/NewsGen/09-2005/msg32.html

- Breakthrough In Micro-device Fabrication Combines Biology And
   Synthetic Chemistry
   Nanostructured micro-devices may be mass produced at a lower cost, and
   with a wider variety of shapes and compositions than ever before.
   http://hum-molgen.org/NewsGen/09-2005/msg31.html

- Discovery May Provide Novel Method To Generate Medically Useful
   Proteins
   C-type lectin fold as an evolutionary solution for massive sequence
   variation.
   http://hum-molgen.org/NewsGen/09-2005/msg30.html

- Old Drug Shows New Promise For Huntington's Disease
   Clioquinol down-regulates mutant huntingtin expression in vitro and
   mitigates pathology in a Huntington's disease mouse model.
   http://hum-molgen.org/NewsGen/09-2005/msg29.html

- New Drug Effective For Rheumatoid Arthritis
   Abatacept for rheumatoid arthritis refractory to tumor necrosis factor
   alpha inhibition.
   http://hum-molgen.org/NewsGen/09-2005/msg28.html

- Malaria: Sequence of Infection Revealed
   Study supplants earlier theories on how the malaria parasite spreads
   from the red blood cells it infects.
   http://hum-molgen.org/NewsGen/09-2005/msg27.html

- Blocking Virus Entry
   Defensins, known to prevent viruses from entering cells, appear to do
   so by preventing the virus from merging to cells' outer membrane.
   http://hum-molgen.org/NewsGen/09-2005/msg26.html

- Benefits of Digital Mammography
   Women with Dense Breasts, Women Younger than 50, and Those Who are
   Perimenopausal May Benefit from Digital Mammograms
   http://hum-molgen.org/NewsGen/09-2005/msg25.html

- Who works together with whom?
   Unique Map Created of Human Protein Interactions
   http://hum-molgen.org/NewsGen/09-2005/msg24.html

- Contact Genetic News editors
   WWW: http://hum-molgen.org/NewsGen/editors.html
   E-mail: news@hum-molgen.org


Biomedical Positions
http://hum-molgen.org/positions/

- Call for Assistant News Editors
   To further strengthen our news section we are currently looking for:
   Assistant Editors for the HUM-MOLGEN News section
   http://hum-molgen.org/NewsGen/04-2003/msg01.html

- Write a position announcement
   http://hum-molgen.org/flyer/positions.pdf
   1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register
   2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login


Literature
http://hum-molgen.org/literature/

- Klipp et al. 2005. Systems Biology in Practice. 1st ed.
   Concepts, Implementation and Application
   http://hum-molgen.org/literature/09-2005/msg03.html

- Sipe et al. 2005. Amyloid Proteins. 1st Ed.
   The Beta Sheet Conformation and Disease, 2 Volumes
   http://hum-molgen.org/literature/09-2005/msg02.html

- Schleef et al. 2005. DNA-Pharmaceuticals. 1st ed.
   Formulation and Delivery in Gene Therapy, DNA Vaccination and
   Immunotherapy
   http://hum-molgen.org/literature/09-2005/msg01.html


Biotechnical requests and sources
http://hum-molgen.org/biotechnology


Events in bioscience and medicine
http://hum-molgen.org/meetings/

- Post event (free)
   http://hum-molgen.de/cgi-bin/meetings.pl?login


Registry of Biomedical Companies (1178 active entries)
http://hum-molgen.org/companies/


Mailing List Administration (Join or leave the list)
http://hum-molgen.org/subscribe-na/


Feedback
contact admin@hum-molgen.org


Advertise at HUM-MOLGEN
http://hum-molgen.org/flyer/advertise.pdf
contact FS Zollmann (dialogue@hum-molgen.org)

__________________________________________________________________________

   Discovery on Target 2005

   Target Discovery and Target Validation Strategies
   October 18-21, 2005 - Boston, MA

   http://hum-molgen.org/promotion-DoT
__________________________________________________________________________ 




   
 
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