HUM-MOLGEN archive: HUM-MOLGEN News Alert

__________________________________________________________________________ Discovery on Target 2005 Target Discovery and Target Validation Strategies October 18-21, 2005 - Boston, MA http://hum-molgen.org/promotion-DoT __________________________________________________________________________ INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS HUM-MOLGEN News Alert - September 07, 2005 - http://hum-molgen.org Genetic News by T.M. D'Souza, T. Dalaya, J. Mill, R. Nemade, D. Sharma, F.S. Zollmann http://hum-molgen.org/NewsGen - Stem Cell Instability Further Down The Line Study reports that human embryonic stem cell lines cultured for a long period of time develop changes in their genomes that may make them unusable for therapeutic purposes. http://hum-molgen.org/NewsGen/09-2005/msg23.html - Detecting Prions In Blood Research may help minimize the spread of prion diseases in the human body. http://hum-molgen.org/NewsGen/09-2005/msg22.html - A Key Initiator Of Allergy And Asthma Finding opens up new ways of studying how disabling lung inflammation may be prevented. http://hum-molgen.org/NewsGen/09-2005/msg21.html - Triggering New Sensors For Virus Infection Research identifying a new response factor triggered by intracellular sensors of viruses may open up new ways of enhancing our ability to fight infections. http://hum-molgen.org/NewsGen/09-2005/msg20.html - Genetic Counseling for Fragile X Syndrome: Updated Recommendations of the National Society of Genetic Counselors These recommendations describe the minimum standard criteria for genetic counseling and testing of individuals and families with fragile X syndrome. http://hum-molgen.org/NewsGen/09-2005/msg19.html - Policy Recommendations for Carrier Testing and Predictive Testing in Childhood: A Distinction That Makes a Real Difference Paper examines how five good practice position statements from Canada, UK and USA, produce different recommendations for carrier testing and predictive testing. http://hum-molgen.org/NewsGen/09-2005/msg18.html - Modeling Metastasis Two studies report findings that improve our understanding of metastasis. http://hum-molgen.org/NewsGen/09-2005/msg17.html - Evolution Discounts Errors Research may shed new light on how to evolve genetic complexity, a key hurdle associated with the development of life on Earth. http://hum-molgen.org/NewsGen/09-2005/msg16.html - Reproductive Biology: Enhancing Sperm Vitality Researchers report the application of a new hybrid polymer that boosts antioxidant levels in porcine sperm, enhancing both vitality and lifespan. http://hum-molgen.org/NewsGen/09-2005/msg15.html - Islet Transplantation for Diabetics Registry Sheds Light on Procedure's Risks and Benefits http://hum-molgen.org/NewsGen/09-2005/msg14.html - Genomics of Inflammation Approximately 5000 genes fluctuate in response to a inflammatory stimulus. http://hum-molgen.org/NewsGen/09-2005/msg13.html - Chimps & Humans - Very Similar Indeed You share 96% of your DNA with chimpanzees, an international consortium reports. http://hum-molgen.org/NewsGen/09-2005/msg12.html - U.S. & India - Vision Research Agreement Both countries commit to expand and collaborate on vision research. http://hum-molgen.org/NewsGen/09-2005/msg11.html - Fruit Fiber May Help Effects of Second-Hand Smoke New study finds that adults who were exposed to second hand smoke as children could reduce the resulting chronic cough by eating more fruit and soy fiber. http://hum-molgen.org/NewsGen/09-2005/msg10.html - Cancer Drug Target Chk1 May Also Be Source Of Drug Resistance New findings suggest balancing Chk1 activity will produce less toxic cancer drugs. http://hum-molgen.org/NewsGen/09-2005/msg09.html - Pinpointing The Cause Of A Neurodegenerative Disorder The AXH Domain of Ataxin-1 Mediates Neurodegeneration through Its Interaction with Gfi-1/Senseless Proteins. http://hum-molgen.org/NewsGen/09-2005/msg08.html - Unexpected Features Of Anthrax Toxin May Lead To New Types Of Therapies Receptor-specific requirements for anthrax toxin delivery into cells http://hum-molgen.org/NewsGen/09-2005/msg07.html - Studies Find Possible Drug Targets For Improving Vascular Health Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. http://hum-molgen.org/NewsGen/09-2005/msg06.html - Scientists Find That Protein Controls Aging By Controlling Insulin Suppression of Aging in Mice by the Hormone Klotho. http://hum-molgen.org/NewsGen/09-2005/msg05.html - A Step Closer To A Malaria Vaccine Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket. http://hum-molgen.org/NewsGen/09-2005/msg04.html - Improving The Potential Of Cancer Vaccines Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function http://hum-molgen.org/NewsGen/09-2005/msg03.html - A double punch for female survival Achieving equality between the sexes can be a challenge even for single cells. http://hum-molgen.org/NewsGen/09-2005/msg02.html - Public collections of DNA and RNA sequence reach 100 gigabases The world's three leading public repositories for DNA and RNA sequence information have reached 100 gigabases [100,000,000,000 bases; the 'letters' of the genetic code] of sequence. http://hum-molgen.org/NewsGen/09-2005/msg01.html - Hand Held Medical Lab Hand-held Device Would Test Residents of Remote Villages for Malaria, Other Endemic Diseases. http://hum-molgen.org/NewsGen/08-2005/msg44.html - Aftermath of Miscarriage: Drug Offers Alternative to Surgical Treatment Misoprostol, a drug first used to reduce the risk of stomach ulcers in people taking certain types of painkillers can also be used in place of surgical vacuum aspiration. http://hum-molgen.org/NewsGen/08-2005/msg43.html - The brain chemical for cravings? Orexin, a brain chemical involved in feeding behavior, arousal, and sleep, may also plays a role in reward function and drug-seeking behavior. http://hum-molgen.org/NewsGen/08-2005/msg42.html - Neurons That Know The Odds Study reports that neurons in a part of the brain called the posterior cingulate cortex represent the riskiness of choices in monkeys. http://hum-molgen.org/NewsGen/08-2005/msg41.html - New Treatment Against SARS Effective In Monkeys Small interfering RNAs, short RNA sequences that can inhibit gene expression, are effective against infection with the severe acute respiratory syndrome (SARS) virus in monkeys. http://hum-molgen.org/NewsGen/08-2005/msg38.html - Study Of Lymph Vessels Makes A Leap Scientists present tadpoles of the African clawed frog Xenopus laevis as a model for investigating the development of lymph vessels. http://hum-molgen.org/NewsGen/08-2005/msg37.html - Avoiding New Food Allergens Discussions on the steps taken to detect new food allergens from genetically modified plants and the limitations of these safeguard measures. http://hum-molgen.org/NewsGen/08-2005/msg35.html - Passport For Emigrating Immune Cells Two reports suggest exit of immune cells from peripheral tissues does not passively occur but requires the expression of a specialized receptor called CCR7. http://hum-molgen.org/NewsGen/08-2005/msg34.html - Unwinding Fanconi Anemia Five studies provide insight into the mechanism underlying the chromosomal instability that characterizes the disease Fanconi anemia. http://hum-molgen.org/NewsGen/08-2005/msg32.html - Seeing Cathepsin The activity of cathepsins, cysteine proteases involved in a number of stages of tumor development, is visualized in a cellular model of a tumor microenvironment. http://hum-molgen.org/NewsGen/08-2005/msg31.html - Viewing Receptor Clusters In A Heart Beat Researchers report the use of a high-resolution imaging technique to visualize heart cell receptor clusters for the first time. http://hum-molgen.org/NewsGen/08-2005/msg30.html - Antibiotic Assembly Line Scientists have turned bacteria into miniature factories for producing novel types of antimicrobial compounds at unprecedented rates. http://hum-molgen.org/NewsGen/08-2005/msg29.html - Nature INSIGHT Review Article: The Challenges Of Hepatitis C Combinations of multiple drugs will be required for the successful treatment of hepatitis C virus (HCV). http://hum-molgen.org/NewsGen/08-2005/msg28.html - Hair And Telomere Scientists describe how activating the protein in skin cells results in rapid hair growth. http://hum-molgen.org/NewsGen/08-2005/msg27.html - A Newly Discovered Pathway To Haemoglobin Production A study provides a new link between two fundamental processes - haem production and the formation of iron-sulphur clusters on proteins. http://hum-molgen.org/NewsGen/08-2005/msg25.html - A Rewarding View On Orexin Cells Activation of neurons that contain the neurotransmitter orexin in the lateral hypothalamus is proportionally linked to food- and drug-seeking behaviours in rats. http://hum-molgen.org/NewsGen/08-2005/msg24.html - Contact Genetic News editors WWW: http://hum-molgen.org/NewsGen/editors.html E-mail: news@hum-molgen.org Biomedical Positions http://hum-molgen.org/positions/ - Call for Assistant News Editors To further strengthen our news section we are currently looking for: Assistant Editors for the HUM-MOLGEN News section http://hum-molgen.org/NewsGen/04-2003/msg01.html - Write a position announcement http://hum-molgen.org/flyer/positions.pdf 1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register 2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login DIAGnostics - Clinical Research (professional requests) http://hum-molgen.org/clinical-research/ - Post diagnostic request / call for collaboration http://hum-molgen.org/diagnostic-posting or contact admin@hum-molgen.org Literature http://hum-molgen.org/literature/ Biotechnical requests and sources http://hum-molgen.org/biotechnology Events in bioscience and medicine http://hum-molgen.org/meetings/ - Post event (free) http://hum-molgen.de/cgi-bin/meetings.pl?login Registry of Biomedical Companies (1157 active entries) http://hum-molgen.org/companies/ Mailing List Administration (Join or leave the list) http://hum-molgen.org/subscribe-na/ Feedback contact admin@hum-molgen.org Advertise at HUM-MOLGEN http://hum-molgen.org/flyer/advertise.pdf contact FS Zollmann (dialogue@hum-molgen.org) __________________________________________________________________________ Discovery on Target 2005 Target Discovery and Target Validation Strategies October 18-21, 2005 - Boston, MA http://hum-molgen.org/promotion-DoT __________________________________________________________________________