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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - September 07, 2005
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Wed, 07 Sep 2005 13:55:56 +0200

__________________________________________________________________________

   Discovery on Target 2005

   Target Discovery and Target Validation Strategies
   October 18-21, 2005 - Boston, MA

   http://hum-molgen.org/promotion-DoT
__________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - September 07, 2005 - http://hum-molgen.org


Genetic News
by T.M. D'Souza, T. Dalaya, J. Mill, R. Nemade, D. Sharma, F.S. Zollmann
http://hum-molgen.org/NewsGen

- Stem Cell Instability Further Down The Line
   Study reports that human embryonic stem cell lines cultured for a long
   period of time develop changes in their genomes that may make them
   unusable for therapeutic purposes.
   http://hum-molgen.org/NewsGen/09-2005/msg23.html

- Detecting Prions In Blood
   Research may help minimize the spread of prion diseases in the human
   body.
   http://hum-molgen.org/NewsGen/09-2005/msg22.html

- A Key Initiator Of Allergy And Asthma
   Finding opens up new ways of studying how disabling lung inflammation
   may be prevented.
   http://hum-molgen.org/NewsGen/09-2005/msg21.html

- Triggering New Sensors For Virus Infection
   Research identifying a new response factor triggered by intracellular
   sensors of viruses may open up new ways of enhancing our ability to
   fight infections.
   http://hum-molgen.org/NewsGen/09-2005/msg20.html

- Genetic Counseling for Fragile X Syndrome: Updated Recommendations of
   the National Society of Genetic Counselors
   These recommendations describe the minimum standard criteria for
   genetic counseling and testing of individuals and families with
   fragile X syndrome.
   http://hum-molgen.org/NewsGen/09-2005/msg19.html

- Policy Recommendations for Carrier Testing and Predictive Testing in
   Childhood: A Distinction That Makes a Real Difference
   Paper examines how five good practice position statements from Canada,
   UK and USA, produce different recommendations for carrier testing and
   predictive testing.
   http://hum-molgen.org/NewsGen/09-2005/msg18.html

- Modeling Metastasis
   Two studies report findings that improve our understanding of
   metastasis.
   http://hum-molgen.org/NewsGen/09-2005/msg17.html

- Evolution Discounts Errors
   Research may shed new light on how to evolve genetic complexity, a key
   hurdle associated with the development of life on Earth.
   http://hum-molgen.org/NewsGen/09-2005/msg16.html

- Reproductive Biology: Enhancing Sperm Vitality
   Researchers report the application of a new hybrid polymer that boosts
   antioxidant levels in porcine sperm, enhancing both vitality and
   lifespan.
   http://hum-molgen.org/NewsGen/09-2005/msg15.html

- Islet Transplantation for Diabetics
   Registry Sheds Light on Procedure's Risks and Benefits
   http://hum-molgen.org/NewsGen/09-2005/msg14.html

- Genomics of Inflammation
   Approximately 5000 genes fluctuate in response to a inflammatory
   stimulus.
   http://hum-molgen.org/NewsGen/09-2005/msg13.html

- Chimps & Humans - Very Similar Indeed
   You share 96% of your DNA with chimpanzees, an international
   consortium reports.
   http://hum-molgen.org/NewsGen/09-2005/msg12.html

- U.S. & India - Vision Research Agreement
   Both countries commit to expand and collaborate on vision research.
   http://hum-molgen.org/NewsGen/09-2005/msg11.html

- Fruit Fiber May Help Effects of Second-Hand Smoke
   New study finds that adults who were exposed to second hand smoke as
   children could reduce the resulting chronic cough by eating more fruit
   and soy fiber.
   http://hum-molgen.org/NewsGen/09-2005/msg10.html

- Cancer Drug Target Chk1 May Also Be Source Of Drug Resistance
   New findings suggest balancing Chk1 activity will produce less toxic
   cancer drugs.
   http://hum-molgen.org/NewsGen/09-2005/msg09.html

- Pinpointing The Cause Of A Neurodegenerative Disorder
   The AXH Domain of Ataxin-1 Mediates Neurodegeneration through Its
   Interaction with Gfi-1/Senseless Proteins.
   http://hum-molgen.org/NewsGen/09-2005/msg08.html

- Unexpected Features Of Anthrax Toxin May Lead To New Types Of
   Therapies
   Receptor-specific requirements for anthrax toxin delivery into cells
   http://hum-molgen.org/NewsGen/09-2005/msg07.html

- Studies Find Possible Drug Targets For Improving Vascular Health
   Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated
   angiogenesis.
   http://hum-molgen.org/NewsGen/09-2005/msg06.html

- Scientists Find That Protein Controls Aging By Controlling Insulin
   Suppression of Aging in Mice by the Hormone Klotho.
   http://hum-molgen.org/NewsGen/09-2005/msg05.html

- A Step Closer To A Malaria Vaccine
   Structure of AMA1 from Plasmodium falciparum reveals a clustering of
   polymorphisms that surround a conserved hydrophobic pocket.
   http://hum-molgen.org/NewsGen/09-2005/msg04.html

- Improving The Potential Of Cancer Vaccines
   Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell
   function
   http://hum-molgen.org/NewsGen/09-2005/msg03.html

- A double punch for female survival
   Achieving equality between the sexes can be a challenge even for
   single cells.
   http://hum-molgen.org/NewsGen/09-2005/msg02.html

- Public collections of DNA and RNA sequence reach 100 gigabases
   The world's three leading public repositories for DNA and RNA sequence
   information have reached 100 gigabases [100,000,000,000 bases; the
   'letters' of the genetic code] of sequence.
   http://hum-molgen.org/NewsGen/09-2005/msg01.html

- Hand Held Medical Lab
   Hand-held Device Would Test Residents of Remote Villages for Malaria,
   Other Endemic Diseases.
   http://hum-molgen.org/NewsGen/08-2005/msg44.html

- Aftermath of Miscarriage: Drug Offers Alternative to Surgical
   Treatment
   Misoprostol, a drug first used to reduce the risk of stomach ulcers in
   people taking certain types of painkillers can also be used in place
   of surgical vacuum aspiration.
   http://hum-molgen.org/NewsGen/08-2005/msg43.html

- The brain chemical for cravings?
   Orexin, a brain chemical involved in feeding behavior, arousal, and
   sleep, may also plays a role in reward function and drug-seeking
   behavior.
   http://hum-molgen.org/NewsGen/08-2005/msg42.html

- Neurons That Know The Odds
   Study reports that neurons in a part of the brain called the posterior
   cingulate cortex represent the riskiness of choices in monkeys.
   http://hum-molgen.org/NewsGen/08-2005/msg41.html

- New Treatment Against SARS Effective In Monkeys
   Small interfering RNAs, short RNA sequences that can inhibit gene
   expression, are effective against infection with the severe acute
   respiratory syndrome (SARS) virus in monkeys.
   http://hum-molgen.org/NewsGen/08-2005/msg38.html

- Study Of Lymph Vessels Makes A Leap
   Scientists present tadpoles of the African clawed frog Xenopus laevis
   as a model for investigating the development of lymph vessels.
   http://hum-molgen.org/NewsGen/08-2005/msg37.html

- Avoiding New Food Allergens
   Discussions on the steps taken to detect new food allergens from
   genetically modified plants and the limitations of these safeguard
   measures.
   http://hum-molgen.org/NewsGen/08-2005/msg35.html

- Passport For Emigrating Immune Cells
   Two reports suggest exit of immune cells from peripheral tissues does
   not passively occur but requires the expression of a specialized
   receptor called CCR7.
   http://hum-molgen.org/NewsGen/08-2005/msg34.html

- Unwinding Fanconi Anemia
   Five studies provide insight into the mechanism underlying the
   chromosomal instability that characterizes the disease Fanconi anemia.
   http://hum-molgen.org/NewsGen/08-2005/msg32.html

- Seeing Cathepsin
   The activity of cathepsins, cysteine proteases involved in a number of
   stages of tumor development, is visualized in a cellular model of a
   tumor microenvironment.
   http://hum-molgen.org/NewsGen/08-2005/msg31.html

- Viewing Receptor Clusters In A Heart Beat
   Researchers report the use of a high-resolution imaging technique to
   visualize heart cell receptor clusters for the first time.
   http://hum-molgen.org/NewsGen/08-2005/msg30.html

- Antibiotic Assembly Line
   Scientists have turned bacteria into miniature factories for producing
   novel types of antimicrobial compounds at unprecedented rates.
   http://hum-molgen.org/NewsGen/08-2005/msg29.html

- Nature INSIGHT Review Article: The Challenges Of Hepatitis C
   Combinations of multiple drugs will be required for the successful
   treatment of hepatitis C virus (HCV).
   http://hum-molgen.org/NewsGen/08-2005/msg28.html

- Hair And Telomere
   Scientists describe how activating the protein in skin cells results
   in rapid hair growth.
   http://hum-molgen.org/NewsGen/08-2005/msg27.html

- A Newly Discovered Pathway To Haemoglobin Production
   A study provides a new link between two fundamental processes - haem
   production and the formation of iron-sulphur clusters on proteins.
   http://hum-molgen.org/NewsGen/08-2005/msg25.html

- A Rewarding View On Orexin Cells
   Activation of neurons that contain the neurotransmitter orexin in the
   lateral hypothalamus is proportionally linked to food- and
   drug-seeking behaviours in rats.
   http://hum-molgen.org/NewsGen/08-2005/msg24.html

- Contact Genetic News editors
   WWW: http://hum-molgen.org/NewsGen/editors.html
   E-mail: news@hum-molgen.org


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__________________________________________________________________________

   Discovery on Target 2005

   Target Discovery and Target Validation Strategies
   October 18-21, 2005 - Boston, MA

   http://hum-molgen.org/promotion-DoT
__________________________________________________________________________





   
 
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