HUM-MOLGEN archive: NEWS: in Bioscience and Medicine

************************************************************** HUM-MOLGEN News in Bioscience and Medicine ************************************************************** News in Bioscience and Medicine: http://www.informatik.uni-rostock.de/HUM-MOLGEN/NewsGen/ HUM-MOLGEN WWW: http://www.informatik.uni-rostock.de/HUM-MOLGEN/ http://linkage.rockefeller.edu/hum-molgen/ -------------------------------------------------------------------- Summary of recent postings (selection): -------------------------------------------------------------------- 1 | IMMUNOGENETICS IMGT DATABASE 2 | GeneCards: a new database integrating information about gene functions 3 | GDB - What's New 4 | Resources for Molecular Cytogenetics 5 | IXDB - the X chromosome WWW site 6 | How to announce new Internet resources, press releases etc. -------------------------------------------------------------------- 1 | IMMUNOGENETICS IMGT DATABASE WWW: http://www.ebi.ac.uk/imgt/ E-mail: malik@ebi.ac.uk Professor Marie-Paule LEFRANC Laboratoire d'ImmunoGenetique Moleculaire, LIGM UMR CNRS 9942, Institut de Genetique Moleculaire BP 5051, 1919 route de Mende, 34033 MONTPELLIER Cedex 1 FRANCE Telephone: (33) 67 61 36 34 FAX : (33) 67 04 02 31/67 04 02 45 e-mail : lefranc@ligm.crbm.cnrs-mop.fr INTRODUCTION ============ The ImMunoGeneTics database, IMGT, is an integrated specialised database containing nucleotide sequence information of genes important in the function of the immune system. It collects and annotates sequences belonging to the immunoglobulin superfamily which are involved in immune recognition, these are the B cell antigen receptor (Immunoglobulin or Ig), the T cell antigen receptor (TCR) (LIGM-database) and the class I and class II molecules of the Human Leucocyte Antigens (HLA) system (HLA-database). IMGT/LIGM DATABASE ================== An integrated immumogenetics database (IMGT/LIGM) specialising in Ig and TcR is under development through collaboration between LIGM, IFG and EMBL oustation EBI. This database consists of the Ig and TcR sequence entries. Collaborators: Release 96.11 contains 7937 fully annotated sequence entries. LIGM Montpellier :Marie-Paule Lefranc (coordinator) Veronique Giudicelli,Denys Chaume EMBL-EBI :Ansar Malik IFG :Werner Mueller ACCESS/DATA DISTRIBUTION ======================== SRS server: http://www.ebi/srs/srsc NOTE: Selecting this option will bring you to the SRS qerry interface page, where you have to select "search Sequence Libraries" WWW server: http://www.ebi.ac.uk/imgt/ FTP server: ftp.ebi.ac.uk/pub/databases/imgt E_MAIL server: email netserv@ebi.ac.uk -- send "help IMGT" in the mail body. This database is available on CD-ROM as an acompanying database to the EMBL Nucleotide Sequence Database at nominal cost. Ansar Malik Ph.D | Email:Malik@ebi.ac.uk EBI - European Bioinformatics Institute | URL: http://www.ebi.ac.uk Hinxton Hall, Hinxton | Tel: +44 (1223) 494417 Cambridge CB10 1RQ, UK | Fax: +44 (1223) 494968 -------------------------------------------------------------------- 2 | GeneCards: a new database integrating information about gene functions WWW: http://bioinfo.weizmann.ac.il/cards/ E-mail: lvrebhan@bioinfo.weizmann.ac.il This new service presents extracts of the data stored in public databases like GDB, OMIM and SWISS-PROT with the intention of facilitating a brief overview of the cellular functions of the products of a gene, the diseases in which mutations have been found, and much more. For example, see GeneCards for the famous BRCA1 or TP53 genes. -------------------------------------------------------------------- 3 | GDB - What's New WWW: http://gdbwww.gdb.org/ E-mail: pfoster@gdb.org 1.Release of Mapview 2.0 Mapview 2 is a Java applet that displays multiple maps with common markers indicated by alignment lines. Whole maps or slices can be displayed. Users will have the options of viewing maps in either Mapview 1 or 2. For help retrieving a map or maps, see Access Points to GDB. 2.Universal Coordinate Querying Another option for searching on the basis of location has been added to the query forms. All Localizations, immediately following Cytogenetic Localization on the query forms, will use a specified location to search for Genomic Segments (and its subclasses, amplimers, genes, clones) across all maps in GDB simultaneously based on a common coodinate system. 3.Other New Features The Order attribute of GenomicSegment and its subclasses has been renamed to Related Segments. The Order class has been renamed to Relationships between Genomic Segments. The menus that border the top of the details forms have been reorganized. When retrieving sequence information from a detail form (Nucleic Acid Sequences), you will be asked to choose a sequence database, either GSDB (Genome Sequence Database) or GenBank (at NCBI). This selection will become your default database for future sequence retrievals, but you can change your preference at any time. 4.Large Data Sets in GDB (1-Dec-96) Source Data Type Cal Tech BAC Library Image Consortium Clones Roswell Park Cancer Institute PAC Libraries Science Human Transcript Maps Stanford Radiation Hybrid Maps Whitehead Institute Radiation Hybrid Maps CHLC Linkage Maps Genethon Linkage Maps -------------------------------------------------------------------- 4 | Resources for Molecular Cytogenetics WWW: http://bioserver.uniba.it/fish/rocchi/welcome.html E-mail: rocchi@area.ba.cnr.it We built up a new Web site on Molecular Cytogenetic Resources. Most of them are partial chromosome paints derived from somatic cell hybrids. They are free available to the scientific community. This is the Web address: http://bioserver.uniba.it/fish/rocchi/welcome.html Mariano Rocchi -------------------------------------------------------------------- 5 | IXDB - the X chromosome WWW site WWW: http://www.mpimg-berlin-dahlem.mpg.de/~xteam/ E-mail: leser@mpimg-berlin-dahlem.mpg.de The Max-Planck-Institute for Molecular Genetics in Berlin, Germany, would like to announce the availability of IXDB via the WWW. IXDB is a new database which stores information related to the physical mapping of the human X chromosome. It also stores data about genes, maps, contigs and several clone libraries. A graphical map display will be released soon. Objects are provided with links to other WWW-databases whereever possible. Comments and corrections are always welcome. Ulf Leser -------------------------------------------------------------------- 6 | How to announce new Internet resources, press releases etc. You can announce (free) new Internet resources, press releases etc. at http://www.informatik.uni-rostock.de/cgi-bin/HMB/NewsGen/vw3news?postF For other announcements please take a look at http://www.informatik.uni-rostock.de/HUM-MOLGEN/hum/submit.html -------------------------------------------------------------------- Neither the owner nor the editors of HUM-MOLGEN can be held liable in any way for the contents, or part of the contents, or even phrases of messages appearing on HUM-MOLGEN or it's TOPICs. Responsibility for the (contents of) messages solely rests with the sender of these messages. -------------------------------------------------------------------- HUM-MOLGEN - Internet Communication Forum in Human Genetics E-mail: HUM-MOLGEN@nic.surfnet.nl WWW: http://www.informatik.uni-rostock.de/HUM-MOLGEN/ http://linkage.rockefeller.edu/hum-molgen/ Phone: 020-566 4598 (The Netherlands), (206) 386-2101 (USA) Fax: 020-691 6521 (The Netherlands), (206) 386-2555 (USA) -------------------------------------------------------------------- ************************************************************************ Dr. Arthur A.B. Bergen Department of Ophthalmogenetics The Netherlands Ophthalmic Research Institute (IOI) Royal Academy of Sciences of the Netherlands (KNAW) ** Snail-mail: ** ** FAX: ** ** E-mail: ** P.O.Box 12141 (+31)206916521 A.Bergen@IOI.KNAW.NL 1100 AC Amsterdam The Netherlands ************************************************************************