HUM-MOLGEN archive: LITE: New: Preview Molecular Medicine

Note from the editor: As a service to the genetics community from The Picower Institute Press and Blackwell Science, HUM-MOLGEN subscribers will receive the TOC preview of the Journal "Molecular Medicine" for FREE under the LITE TOPIC. Please find the first six TOCs, including the july 'in press' issue, below. In general, We intend to send you no more than than 10 TOC previews (per month), with a selection system based on the highest citation index and HUM-MOLGEN direct interest score. A number of additional, special interest TOCs will be send to you under a specific TOPIC. Take it LITEly! Arthur Bergen ********************************************************************** Molecular Medicine TABLE OF CONTENTS Premier Issue, November 1994 Editorial Molecular Medicine: the Future of Biomedical Science and Clinical Practice 1 A. Cerami and K.S. Warren Opinion Gene Therapy: Hopes, Hypes and Hurdles 2 I.M. Verma In This Issue Summaries of Articles 4 Original Articles Role of Macrophage Oxidative Burst in the Action of Anthrax Lethat Toxin 7 P. Hanna, B. Kruskal, R.A. Ezekowitz, B. Bloom, and R.J. Collier* High Prion and PrPSc Levels but Delayed Onset of Disease in Scrapie-Inoculated 19 Mice Heterozygous for a Disrupted PrP Gene H. Beler, A. Raber, A. Sailer, M. Fischer, A. Aguzzi, and C. Weissmann Pentoxifylline and Other Protein Kinase C Inhibitors Down-Regulate HIV-LTR 31 NF-kB Induced Gene Expression D.K. Biswas, C.M. Ahlers, B.J. Dezube, and A.B. Pardee The Evolutionarily Conserved Ribosomal Protein L23 and the Cationic Urease 44 b-Subunit of Yersinia enterocolitica O:3 Belong to the Immunodominant Antigens of Yersinia-Triggered Reactive Arthritis A.K.H. Mertz, A. Daser, M. Skurnik, K. Wiesmller, S. Batsford, J. Braun P. Wu, H. Appel, A. Distler, and J. Sieper Submitted by N.A. Mitchison Clonal Hematopoiesis and Acquired Thalassemia in Common Variable 56 Immunodeficiency M. Belickova, H.W. Schroeder, Jr., Y.L. Guan, J. Brierre, S. Berney, M.D. Cooper, and J.T. Prchal X Chromosome Inactivation Patterns Correlate with Fetal-Placental Anatomy 62 in Monozygotic Twin Pairs: Implications for Immune Relatedness and Concordance for Autoimmunity V. Trejo, C. Derom, A.Vlietinck, W. Ollier, A. Silman, G. Ebers, R. Derom, and P.K. Gregersen Submitted by K.S. Warren Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates 71 Tissue Repair R. Bucala, L. Spiegel, J. Chesney, M. Hogan, and A. Cerami Glucocerebrosidase Mutations in Gaucher Disease 82 E. Beutler, A. Demina, and T. Gelbart Lipopolysaccharide Signals Activation of Tumor Necrosis Factor Biosynthesis 93 through the Ras/Raf-1/MEK/MAPK Pathaway T.D. Geppert, C.E. Whitehurst, P. Thompson, and B. Beutler Submitted by A. Cerami The Molecular Basis of Increased Glomerulosclerosis after Blockade of the renin Angiotensin System in Growth Hormone Transgenic Mice 104 E.P. Peten, L.J. Striker, A. Fogo, I. Ichikawa, A. Patel, and G.E. Striker Submitted by D.K. Peters Molecular Medicine Database 116 Instructions for Authors 117 *Underlining denotes contributing editor. Molecular Medicine ********************************************************************************** TABLE OF CONTENTS January 1995 Editorial Molecular Medicine Society 119 D.G. Nathan Mini Reviews Angiogenesis Inhibitors Generated by Tumors 120 J. Folkman The Latest Fashions in Skin Disease 123 J.M. Carroll and L.A. Goldsmith In This Issue Summaries of articles 127 Original Articles Odorant Receptors and Desensitization Proteins Colocalize in Mammalian Sperm 130 L.D. Walensky, A.J. Roskams, R.J. Lefkowitz, S.H. Snyder*, and G.V. Ronnett Regulation of Transcription Functions of the p53 Tumor Suppressor by the mdm-2 Oncogene 142 J. Chen, J. Lin, and A. J. Levine Differential Expression of Human Tissue Factor in Normal Mammary Epithelial Cells and in Carcinomas 153 Z. Chen and R. Sager Association Between HLA DQB1*03 and Cervical Intra-Epithelial Neoplasia 161 K. Odunsi, G. Terry, L. Ho, J. Bell, J. Cuzick, and T.S. Ganesan Submitted by D.J. Weatherall Adenovirus-Mediated Transfer of the Herpes Simplex Virus Thymidine Kinase Gene Inhibits Vascular Smooth Muscle Cell Proliferation and Neointima Formation Following Balloon Angioplasty of the Rat Carotid Artery 172 M.W. Chang, T. Ohno, D. Gordon, M.M. Lu, G.J. Nabel, E.G. Nabel, and J. M. Leiden Hypoxic Induction of Endothelial Cell Growth Factors in Retinal Cells: 182 Identification and Characterization of Vascular Endothelial Growth Factor (VEGF) as the Mitogen D.T. Shima, A.P. Adamis, N. Ferrara, K-T. Yeo, T.-K. Yeo, R. Allende, J. Folkman, and P. D'Amore Genomic Organization and Sequence of the Human Natural Resistance 194 Associated Macrophage Protein (NRAMP) Gene: Identification and Mapping of a Promoter Region Polymorphism J.M. Blackwell, C.H. Barton, J.K. White, S. Searle, A.-M. Baker, H. Williams, and M.-A. Shaw Submitted by D.K. Peters Expression Cloning of cDNAs that Render Cancer Cells Resistant to Pseudomonas 206 and Diphtheria Toxin and Immunotoxins U. Brinkmann, E. Brinkmann and I. Pastan Nuclear Localization signal of HIV-1 as a Novel Target for Therapeutic 217 Intervention L. Dubrovsky, P. Ulrich, C.M. Feldherr, G.J. Nuovo, K.R. Manogue, A.Cerami, and M. Bukrinsky Molecular Medicine Database 231 Molecular Medicine Calendar 234 Instructions to Authors 236 _________________________________ *Underlining denotes contributing editor. Molecular Medicine ************************************************************************************** TABLE OF CONTENTS March 1995 Editorial A Molecular Medicine Database 239 K.S. Warren Obituary 241 In This Issue Summaries of articles 242 Original Articles Autoantibodies to Neuronal Glutamate Receptors in Patients with Paraneoplastic 245 Neurodegenerative Syndrome Enhance Receptor Activation L.C. Gahring, R.E. Twyman, J.E. Greenlee, and S.W. Rogers Submitted by M.R. Capecchi* An Inhibitor of Macrophage Arginine Transport and Nitric Oxide Production 254 (CNI-1493) Prevents Acute Inflammation and Endotoxin Lethality M. Bianchi, P. Ulrich, O. Bloom, M. Meistrell III, G.A. Zimmerman, H. Schmidtmayerova, M. Bukrinsky, T. Donnelley, R. Bucala, B. Sherry, K.R. Manogue, A.J. Tortolani, A. Cerami, and K.J. Tracey Nramp Transfection Transfers Ity/Lsh/Bcg-related Pleiotropic Effects on 267 Macrophage Activation: Influence on Oxidative Burst and Nitric Oxide Pathways C.H. Barton, S.H. Whitehead, and J.M. Blackwell Submitted by K.S. Warren Construction of a Novel Bifunctional Biogenic Amine Receptor by Two Point 280 Mutations of the H2-Histamine Receptor J. DelValle, I. Gantz, L. Wang, Y.J. Guo, G. Munzert, T. Tashiro, Y. Konda, and T. Yamada Restricted Usage of T Cell Receptor Va/Ja Gene Segments with Different 287 Nucleotide but Identical Amino Acid Sequences in HLA-DR3+ Sarcoidosis Patients J. Grunewald, T. Hultman, A. Bucht, A. Eklund, and H. Wigzell Hemoglobin Switching in Humans is Accompanied by Changes in the Ratio of 297 the Transcription Factors GATA-1 and SP1 E.R. Bacon, N. Dalyot, D. Filon, L. Schreiber, E.A. Rachmilewitz, and A. Oppenheim. Submitted by S.H. Orkin Cell Type-Dependent Modulation of the Dominant Negative Action of Human 306 Mutant Thyroid Hormone b1 Receptors R. Wong, X. Zhu, M.A. Pineda, S. Cheng, and B. Weintraub Submitted by I. Pastan Failure of Aglucerase Infused into Gaucher Disease Patients to Localize in 320 Marrow Macrophages E. Beutler, W. Kuhl, and L.M. Vaughan Immunogenicity and In Vivo Efficacy of Recombinant Plasmodium Falciparum 325 Merozoite Surface Protein-1 in Aotus Monkeys S. Kumar, A. Yadava, D.B. Keister, J.H. Tian, M. Ohl, K.A. Perdue-Greenfield, L.H. Miller, and D. C. Kaslow Molecular Medicine Database 333 Molecular Medicine Calendar 337 Instructions to Authors 339 _________________________________ * Underlining denotes contributing editor. ********************************************************************************* Molecular Medicine TABLE OF CONTENTS May 1995 Editorial The McCarty Award in Molecular Medicine 341 A. Cerami Series: Classics in Molecular Medicine Transforming Biology 342 M. McCarty Avery OT, MacLeod CM, McCarty M. (1944) STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES. J. Exp. Med. 79: 137-158. Series: Molecular Medicine Institutions The Institute of Molecular Medicine, University of Oxford 366 D. Weatherall Opinion The MD PhD Physician Scientist - Endangered Species or the Next Generation? 369 G.J. Nabel In This Issue Summaries of Articles 371 Original Articles Normal and Expanded Huntington's Disease Gene Alleles Produce 374 Distinguishable Proteins Due to Translation Across the CAG Repeat F. Persichetti, C.M. Ambrose, P. Ge, S.M. McNeil, J. Srinidhi, M.A. Anderson, B. Jenkins, G.T. Barnes, M.P. Duyao, L. Kanaley, N.S. Wexler, R.H. Myers, E.D. Bird, J.-P. Vonsattel, M.E. MacDonald, and J.F. Gusella Submitted by S.H. Orkin* Thalidomide Treatment Reduces Tumor Necrosis Factor a Production and 384 Enhances Weight Gain in Patients With Pulmonary Tuberculosis J.M. Tramontana, U. Utaipat, A. Molloy, P. Akarasewi, M. Burroughs, S. Makonakawkeyoon, B. Johnson, J.D. Klausner, W. Rom, and G. Kaplan Submitted by B.R. Bloom Clozapine: Selective Labeling of Sites Resembling 5-HT6 Serotonin Receptors May 398 Reflect Psychoactive Profile C.E. Glatt, A.M. Snowman, D.R. Sibley, and S.H. Snyder Antiviral Drugs from the Nucleoside Analogue Family Block Volume-Activated 407 Chloride Channels M. Gschwentner, A. Susanna, E. W”ll, M. Ritter, U.O. Nagl, A. Schmarda, A. Laich, G.M. Pinggera, H. Ellemunter, H. Huemer, P. Deetjen and M. Paulmichl Submitted by K.S. Warren The Tissue Inhibitor of Metalloproteinases-3 Gene in Breast Carcinoma: 418 Identification of Multiple Polyadenylation Sites and of a Stromal Pattern of Expression J.A. Byrne, C. Tomasetto, N. Rouyer, J.-P. Bellocq, M.-C. Rio, and P. Basset Submitted by P. Chambon LPS and Taxol Activate Lyn Kinase Autophosphorylation in Lpsn, but Not in 428 Lpsd, Macrophages B.E. Henricson, J.M. Carboni, A.L. Burkhardt, and S.N. Vogel Submitted by A. Cerami The MarR Repressor of the Multiple Antibiotic Resistance (mar) Operon in 436 Escherichia coli: Prototypic Member of a Family of Bacterial Regulatory Proteins Involved in Sensing Phenolic Compounds M.C. Sulavik, L.F. Gambino, P.F. Miller Submitted by P. Cuatrecasas Advanced Glycation Endproducts Promote Adhesion Molecule (VCAM-1, ICAM-1) 447 Expression and Atheroma Formation in Normal Rabbits H. Vlassara, H. Fuh, T. Donnelly, and M. Cybulsky Submitted by K.S.Warren Expression of the Von Hippel-Lindau Tumor Suppressor Gene, VHL, in Human 457 Fetal Kidney and During Mouse Embryogenesis P.M. Kessler, S.P. Vasavada, R.R. Rackley, F.-M. Duh, F. Latif, M.I. Lerman, B. Zbar, and B.R.G. Williams Submitted by R. Sager Molecular Medicine Database 467 Molecular Medicine Calendar 472 Instructions to Authors 475 *Underlining denotes contributing editor. Molecular Medicine ************************************************************************************ TABLE OF CONTENTS July 1995 (In Press) Series: Molecular Medicine Institutions Yale s Boyer Center for Molecular Medicine V.T. Marchesi and A.N. Brady Minireviews HIV Accessory Proteins: Emerging Therapeutic Targets R.H. Miller and N. Sarver A Role for T Cells in the Pathogenesis of Treatment-Resistant Lyme Arthritis T. Kamradt, A. Krause, and G.-R. Burmester In This Issue Summaries of Articles Original Articles Burkitt s Lymphoma is a Malignancy of Mature B Cells Expressing Somatically Mutated V Region Genes U. Klein, G. Klein, B. Ehlin-Henriksson, K. Rajewsky*, and R. Keppers Taxol-Induced Mitotic Block Triggers Rapid Onset of a p53-Independent Apoptotic Pathway C.M. Woods, J. Zhu, P.A. McQueney, D. Bollag, and E. Lazarides Submitted by A.J. Levine Nerve Growth Factor (NGF) Prevents Both Neuroretinal Programmed Cell Death and Capillary Pathology in Experimental Diabetes H.-P. Hammes, H.J. Federoff, and M. Brownlee Submitted by A. Cerami Inhibition of Protein Phosphatase 1 Stimulates Secretion of Alzheimer Amyloid Precursor Protein E.F. da Cruz e Silva, O.A.B. da Cruz e Silva, C.T.B.V. Zaia, and P. Greengard Amyloid Formation in Response to b Cell Stress In Vitro, But Not In Vivo, in Islets of Transgenic Mice Expressing Human Islet Amyloid Polypeptide G. Westermark, M.B. Arora, N. Fox, R. Carroll, S.J. Chan, P. Westermark, and D.F. Steiner Gamma-Delta T Cell Receptor Analysis Supports a Role for HSP 70 Selection of Lymphocytes in Multiple Sclerosis Lesions L. Battistini, M. Salvetti, G. Ristori, M. Falcone, C.S. Raine, and C.F. Brosnan. Submitted by B.R. Bloom Variable Response to a Candidate Cancer Vaccine Antigen: MHC Control of the Antibody Response in the Rat to Avian Erythroblastosis Virus (AEV)-Encoded Epithelial Growth Factor Receptor (EGF-R) but not AEV-Encoded Thyroid Hormones Receptor (Ths-R) N.Nardi and N.A.Mitchison Ciliary Neurotrophic Factor (CNTF) Inhibits Brain and Peripheral Tumor Necrosis Factor Production and, When Co-Administered With its Soluble Receptor, Protects Mice Against Lipopolysaccharide (LPS) Toxicity F. Benigni, P. Villa, M.T. Demitri, S. Sacco, J.D. Sipe, L. Lagunowich, N. Panayotatos, and P. Ghezzi Submitted by K.S. Warren Analysis of Families at Risk for Insulin-Dependent Diabetes Reveals that HLA Antigens Influence Progression to Clinical Disease M.C. Honeyman, L.C. Harrison, B. Drummond, P.G. Colman, and B.D. Tait Submitted by G.J.V. Nossal Molecular Medicine Database Molecular Medicine Calendar Instructions to Authors *Underlining denotes contributing editor.