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news archive December 2007

your information resource in human molecular genetics
  • You Must Remember This
    A part of the brain known as the basal ganglia may act to filter out irrelevant information from memory, increasing its apparent capacity.
  • A Mechanical Test For Cancer
    Cancer cells are softer than healthy cells, according to mechanical measurements published online.
  • Passive Immunotherapy Against Hepatitis C
    Delivering antibodies that recognize the hepatitis C virus (HCV) can be therapeutically beneficial in a mouse model.
  • Run Away From Your Depression
    Scientists have discovered a molecule with antidepressant actions, which is produced by the brain as a result of physical exercise.
  • Bad To The Bone
    A drug commonly prescribed to diabetes patients may have negative effects on the bone.
  • Restoring Bacterial Killing In Cystic Fibrosis
    A report published online reveals that high protease levels in the lungs of patients with cystic fibrosis disable immune cells, explaining why CF patients fail to clear lung infections.
  • Fuelling Allergic Inflammation
    Two studies oublished online pinpoint the cellular machinery required to drive allergic reactions.
  • Pathway To Breast Cancer
    Scientists have identified a particular combination of mutations in hereditary breast cancers that typically have a poor prognosis.
  • Genetic Variants Predispose To Lupus
    Individuals with a particular combination of genetic variants near the gene TNFSF4 are at higher risk of developing lupus.
  • Genetic Risk Factor For Psoriasis
    Individuals carrying extra copies of a cluster of genes encoding a family of small antimicrobial proteins are at increased risk of developing psoriasis.
  • Coding Gene Regulation
    Three papers published online analyse a component of chromatin - the complex of DNA and protein that makes up chromosomes - and identify two new modifications that expand the 'chromatin code'.
  • Induced Pluripotent Stem Cells Without Tumours
    Building on their research reported last week, Shinya Yamanaka and colleagues show how to convert adult mouse or human skin cells into cells that resemble embryonic stem cells without using the tumour-causing gene c-Myc.
  • A Double Agent Exposed
    A tumour needs its own network of blood vessels to fuel its growth and so it commandeers factors from its host to help - for example, ones ordinarily active in wound healing.
  • Cell Transplants Offer Hope Against Arrhythmias After A Heart Attack
    Transplants of genetically engineered cells could help to reduce the risk of fatal arrhythmia in the wake of a heart attack.
  • New Compounds Offer Promise For Diabetes Treatment
    Drug researchers have identified a new class of molecule that could help to tackle diabetes, and which mimic the beneficial metabolic effects of a reduced-calorie diet.
  • Rearranging Genomes
    RNA molecules are shown to guide genome rearrangement in new cells.

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