home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

A Mechanical Test For Cancer

  December, 13 2007 10:38
your information resource in human molecular genetics

Cancer cells are softer than healthy cells, according to mechanical measurements published online in Nature Nanotechnology. The results suggest that this mechanical signature may be a powerful way to detect cancer in the clinic and could also have applications in personalized medication.

James Gimzewski and colleagues show that cancer cells taken from the body fluid of patients with suspected lung, breast and pancreas cancer are more than 70% softer than benign cells. Even though the patients had very different clinical histories, the different types of cancer cells showed similar values of stiffness, so the healthy and diseased states could be clearly identified. Moreover, normal cells that looked like cancerous cells could be distinguished with this technique.

'This nanomechanical approach provides a potentially powerful means for detecting cancer along with the other ancillary biomarkers currently used for diagnosis' says Subra Suresh in an accompanying News and Views article. However, before the new approach can be used in the clinic, further tests are needed to explore, among other things, the influence of other existing diseases on the mechanical properties of normal and cancerous cells.

Author contact:

James Gimzewski (University of California, Los Angeles, CA, USA)
E-mail: gim@chem.ucla.edu

Abstract available online.

(C) Nature Nanotechnology press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.