home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Standardized Methods Improve Cancer Diagnosis

 
  December, 21 2006 2:08
your information resource in human molecular genetics
 
     
A set of guidelines for pathologists that may greatly improve the diagnosis of malignant lymphomas are to be published online by Leukemia. In five related papers, a group of leading scientists participating in the EU-supported BIOMED-2 programme report a new test that could be used as an efficient and cost-effective method to diagnose lymphomas.

Malignant lymphomas are cancers of the immune system, which arise from a single malignantly transformed lymphoid cell and consequently have the same clonal rearrangement of immune receptor genes. The Southern Blot technique is traditionally seen as the most effective method for assessing the clonal rearrangements of immune receptor genes that indicate the presence of malignant lymphoma. However, this involves a complex process, requires a large amount of DNA and takes a relatively long time to complete.

The authors of the present studies report that PCR - polymerase chain reaction - clonality testing is a reliable and more efficient diagnostic tool. They make several recommendations for a standardized approach in patients that could be used routinely, and, they believe, that would improve and speed-up the diagnosis of this disease.

Author contact:

JJM van Dongen (Coordinator of BIOMED-2 Concerted Action, Erasmus MC, Rotterdam, The Netherlands)
E-mail: j.j.m.vandongen@erasmusmc.nl

Editorial contact:

Rachel Gonzaga (Leukemia, London, UK)
E-mail: r.gonzaga@nature.com

(C) Leukemia press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.