home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Re-Thinking Obesity

  November, 19 2009 18:13
your information resource in human molecular genetics

Mutations in specific genes fully explain a small but significant subset of patients with obesity and/or type 2 diabetes while genetic factors play a key role in determining susceptibility to both disorders in the broader population, a Review in Nature concludes. Teasing apart the genetics of people with these conditions is helping researchers identify new therapeutic targets, design new drugs and understand the pathophysiology of these complex disorders.

Metabolic diseases, generally thought to be caused by an interaction between heritable factors and environmental influences, pose a growing threat to world-wide public health. Focussing on obesity and type 2 diabetes, Stephen O'Rahilly explores the extent to which human molecular genetics has illuminated our understanding of their underlying mechanisms.

Gone are the days, he argues, when these disorders were viewed solely as a product of our 'food-on-tap' environment. The time may be coming when obesity is viewed not so much as a metabolic disease, but as a heritable neurobehavioural disorder, albeit one highly susceptible to the environment.


Stephen O'Rahilly (University of Cambridge, UK)
E-mail: so104@medschl.cam.ac.uk

(C) Nature press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.