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The Phenotype Of Second And Third Toe Syndactyly Maps To Chromosome 3p21.31

 
  November, 29 2005 11:10
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Evidence For Clinical And Genetic Heterogeneity Of Syndactyly Type I: The Phenotype Of Second And Third Toe Syndactyly Maps To Chromosome 3p21.31

Sajid Malik (1,2), Jörg Schott (1), Syed Wajahat Ali (3), Frank Oeffner (1), Muhammad Amin-ud-Din (3), Wasim Ahmad (2), Karl-Heinz Grzeschik (1) and Manuela C Koch (1)

(1) Zentrum für Humangenetik, Philipps-Universität Marburg, Bahnhofstr. 7, 35037 Marburg, Germany
(2) Department of Biological Sciences, Quaid-I-Azam University, 45320 Islamabad, Pakistan
(3) Department of Biology, Government College, 32200 DG Khan, Pakistan

There is good evidence from the medical literature that type I syndactyly, the most common form of the nonsyndromic syndactylies, is clinically heterogeneous. The authors therefore propose to group the condition into four subtypes, which are all autosomal dominantly inherited: Subtypes 1-4. These subtypes are described in the published articles in the European Journal of Human Genetics (Vol.13, pp. 1268–1274).

Correspondence:

Dr S Malik, Zentrum für Humangenetik, Philipps-Universität Marburg, Bahnhofstr. 7, 35037 Marburg, Germany.
E-mail: malik@staff.uni-marburg.de

Abstract available online.

(C) European Journal of Human Genetics.

Posted by: Tressie Dalaya


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