home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Cutting Cholesterol With RNAi

  November, 23 2004 8:33
your information resource in human molecular genetics
A technique called 'RNA interference' (RNAi) holds tremendous promise as a means to cure ailments by shutting off disease-causing genes; however, it has been difficult to make the technique work in the cells that need it most. In the 11 Nov 2004 issue of Nature (Vol. 432, No. 7014, pp. 173-178), Hans-Peter Vornlocher and colleagues report a simple and ground-breaking new way to use RNAi to cut cholesterol levels in mice. The technique reveals a practical way in which RNAi might be used to treat a broad range of ailments - including coronary artery disease - that affect an animal's body.

The new work shows how RNAi could be used to treat a much broader range of diseases than is currently possible. "It remains to be seen whether [this] approach can be used to silence other disease-related genes in animal models. If so, it should revolutionise the use of RNAi", writes John Rossi in an accompanying News & Views article.


Hans-Peter Vornlocher (Alnylam Pharmaceuticals, Kulmbach, Germany)
E-mail: hpvornlocher@alnylam.de

John Rossi (Beckman Research Institute of the City of Hope, Duarte, CA, USA)
Tel: +1 626 301 8360, E-mail: jrossi@coh.org

(C) Nature press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.