news archive November 2004

• Corautus Genetics Announces Publication of Gene Therapy Approach to Heart Disease in Circulation
  Corautus' technology is currently being tested in a Phase IIb trial known as GENASIS ("Genetic Angiogenic Stimulation Investigational Study")
  
• New Protein “Stop Sign” Alters Blood Vessel Growth
  Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins
  
• A Molecular Light Switch Silences Neurons
  A technical report describes a new technique for rapid, reversible and precise silencing of neural activity that overcomes limitations of past techniques.
  
• How People Learn From Mistakes
  A rare opportunity not only to record from single human brain cells, but also to study the effects of their loss suggests that a certain brain area may be important for our ability to form effective strategies.
  
• Busting Up Gallstones
  A compound that alters the composition of the digestive fluid bile might prevent gallstone formation.
  
• West Nile Virus: Crossing Into The Brain
  Researchers have discovered how West Nile virus enters the brain.
  
• Cancer Spreads
  An Insight in the 18 Nov 2004 issue of Nature captures the excitement in the rapidly advancing field of cancer research.
  
• New Evidence For Cancer Stem Cells
  An original study identifies brain tumour initiating cells and suggests them as new targets for more effective cancer therapies.
  
• Non-Coding RNA Helps To Regulate Insulin
  New study provides hope for diabetes drug development by showing the power of a class of non-coding RNAs thought to regulate gene expression.
  
• Cutting Cholesterol With RNAi
  Scientists report a simple and ground-breaking new way to use RNAi to cut cholesterol levels in mice.
  

• Nicotine Improves Survival In Sepsis
  Research shows that acetylcholine is a physiological inhibitor of inflammation and suggest that molecules related to nicotine might be useful for the treatment of sepsis.
  
• Genetic Signature Of Female Promiscuity
  First study to correlate mating behavior across a range of diverse species to changes in the sequence of a gene involved in reproduction.
  
• Human genome variation and 'race'
  A special issue of the journal Nature Genetics, "Genetics for the Human Race", presents a comprehensive survey of what we currently know about the science of human genetic variation.
  
• Enzyme Baf60c Required For Heart Formation
  Identification of a new molecule that regulates embryonic heart and muscle development in mice may suggest a new way that genes are controlled during organ formation, and provide a clue to how birth defects occur in humans.
  
• Reproductive Biology, Where Next?
  A special section in the 04 Nov 2004 issue of Nature tackles some of the most pressing questions in the field of reproductive biology.
  
• Recycling Nutrients Helps Babies Survive Birth
  Studying newborn mice, scientists show that a cellular process called autophagy ramps up immediately after birth and remains high for several hours, to help them survive the sudden and severe starvation period experienced right after birth.
  
• A Guide To Vascular Development
  Researchers explain for the first time how the cell-surface receptor UNC5B guides blood vessel development.
  
• Crypto Genome Decoded
  Study reveals the genome of Cryptosporidium hominis, a common water-borne parasite that triggers diarrhoea and is sometimes fatal.
  

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