home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Drug Target For Obesity?

 
  October, 13 2006 10:21
your information resource in human molecular genetics
 
     
A molecule that makes mammals feel full up has been identified, and drugs that target it may help to treat obesity.
Appetite is regulated, at least in part, in a brain region called the hypothalamus. In a paper published online by Nature, Masatomo Mori and colleagues show that a fragment of the secreted protein NUCB2, dubbed nesfatin-1, is expressed in this control centre and induces a feeling of satiety.

When nesfatin-1 is injected into the brain, rats eat less and begin to lose weight. When nesfatin-1 is blocked, animals eat more.
Author contact:

Masatomo Mori (Gunma University Graduate School of Medicine, Maebashi, Japan)
E-mail: mmori@med.gunma-u.ac.jp

Abstract available online.

(C) Nature press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.