home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

Gene Therapy Progress And Prospects: Non-Viral Gene Therapy By Systemic Delivery

 
  September, 13 2006 10:11
your information resource in human molecular genetics
 
     
Gene Therapy Progress And Prospects: Non-Viral Gene Therapy By Systemic Delivery

Authors:
S-D Li and L Huang

Author Affiliation:
Division of Molecular Pharmaceutics, School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA

Journal:
Gene Therapy, 2006, 13: 1313-1319

Abstract
Non-viral vectors continue to be an attractive alternative to viral vectors due to their safety, versatility and ease of preparation and scale-up. Over the past few years, investigators have been successful in developing gene carriers that can be targeted to the disease site. Several different delivery vectors for systemic use have been developed by different groups for plasmid DNA and oligonucleotide. Most of them are designed for targeted tumor therapy. The mechanism of inflammatory toxicity, the major toxicity of cationic lipoplex, has been studied and managed. In this review, we focus on the progress made over the last 2 years. We also discuss some future prospects for gene delivery.

Correspondence:
Dr L Huang, Division of Molecular Pharmaceutics, School of Pharmacy, University of North Carolina, CB 7360, 2316 Kerr Hall, Chapel Hill, NC 27599-7360, USA. E-mail: leafh@unc.edu

Full Article available online.

(C) Gene Therapy.

Posted by: Tressie Dalaya


Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2018 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.