home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
 
  HUM-MOLGEN -> Genetic News | search  
 

A Forceful Finding About Atherosclerosis

 
  September, 21 2005 7:30
your information resource in human molecular genetics
 
     
In a cardiovascular disease known as atherosclerosis, plaques accumulate in vessel regions with low or disturbed blood flow. The endothelial cells that line these vessels somehow sense the unusual patterns of mechanical stress on the vessel walls.

In the 15 Sept. 2005 issue of Nature (Vol. 437, No. 7057, pp. 426-431), Martin Alexander Schwartz and his colleagues show that three proteins, which are expressed in vessel endothelial cells, are required for detecting this mechanical stress. They further demonstrate that each protein has a distinct role in converting the mechanical force into a biochemical signal inside the cells. These new findings shed light on how disruptions in blood flow stimulate endothelial cells and trigger the formation of atherosclerotic plaques. Therefore, the results could help lead to the discovery of new drugs to stop the atherosclerotic process from happening.

CONTACT:

Martin Alexander Schwartz (The Scripps Research Institute, La Jolla, CA and University of Virginia, Charlottesville, VA, USA)
E-mail: maschwartz@virginia.edu

(C) Nature press release.


Message posted by: Trevor M. D'Souza

print this article mail this article
Bookmark and Share this page (what is this?)

Social bookmarking allows users to save and categorise a personal collection of bookmarks and share them with others. This is different to using your own browser bookmarks which are available using the menus within your web browser.

Use the links below to share this article on the social bookmarking site of your choice.

Read more about social bookmarking at Wikipedia - Social Bookmarking

Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2017 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.