home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Single-Instrument Human Genome Sequencing

  August, 13 2009 14:52
your information resource in human molecular genetics
The complete genetic makeup of a person has been determined using only a single DNA sequencing machine. The result, published this week in Nature Biotechnology, demonstrates that human genome sequencing -- previously the exclusive domain of large sequencing centers -- is now within reach of an individual laboratory in a matter of weeks.

Several human genomes have been sequenced in the past year -- including that of the first Asian, the first African, and most recently the first Korean person. These genome sequences required concerted effort by many researchers using many sequencing instruments.

Stephen Quake and colleagues sequenced the genome of a Caucasian male using a single DNA sequencing instrument that required less sample preparation than other instruments. They identify instances of genetic variation that distinguish this individual from other sequenced individuals. This methodology and the information garnered could someday be used for personalized medicine since it allows for quicker sequencing.

Author contact:

Stephen Quake (Stanford University, CA, USA)
E-mail: quake@stanford.edu

Abstract available online.

(C) Nature Biotechnology press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2021 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.