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Creation of New Neurons Critical to Antidepressant Action in Mice

 
  August, 11 2003 2:00
your information resource in human molecular genetics
 
     
Blocking the formation of neurons in the hippocampus blocks the behavioral effects of antidepressants in mice, say researchers funded by the National Institutes of Health (NIH). Their finding lends new credence to the proposed role of such neurogenesis in lifting mood. It also helps to explain why antidepressants typically take a few weeks to work, note Rene Hen, Ph.D., Columbia University, and colleagues, who report on their study in the August 8th Science.

For more information, contact:
Jules Asher
NIMH Press Office
(301) 443-4536


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