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Telomerase mutation stops tumor growth

 
  July, 4 2001 3:27
your information resource in human molecular genetics
 
     
UCSF SCIENTISTS HALT TUMOR GROWTH BY MANIPULATING TELOMERASE ENZYME

UCSF researchers report that they were able to slow the growth of human cancer
cells - or cause them to commit suicide altogether -- by creating just a
miniscule mutation in the telomerase enzyme.

The study, conducted in breast and prostate cells grown in culture and in
tumors formed from human breast cancer cells grafted into mice, suggests that
human cancer cells are much more sensitive to disruptions in the telomerase
enzyme than had been thought. The finding hints, the researchers say, at a
possible new strategy for thwarting human cancers.
This study is published in PNAS


Message posted by: Wouter Kalle

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