home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Helping The Immune System

  May, 1 2008 8:25
your information resource in human molecular genetics

Researchers identify a protein involved in blood circulation in tumours and demonstrate that deleting it opens up the tumour to the immune system. The team believe that the protein, RGS5, could be a target for anti-cancer therapy, in particular when combined with approaches that also enhance an anti-tumour immune response.

Formation of new blood vessels in solid tumours, termed angiogenesis, enables tumour enlargement. In Nature, Ruth Ganss and colleagues establish a previously unknown role of RGS5, a signalling molecule, in this process and show that it alters blood vessels. They removed Rgs5 gene function, which leads to normalization of blood vessels within the tumour and allows more immune cells to target it. They conclude that their finding expands potential therapeutic opportunities.


Ruth Ganss (Western Australian Institute for Medical Research, Perth, WA, Australia)
E-mail: ganss@waimr.uwa.edu.au

Abstract available online.

(C) Nature press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.