your information resource in human molecular genetics
Data from the 1970s which appeared to suggest that at the age of 35 years a woman had a similar chance of delivering a child with aneuploidy as experiencing a miscarriage after an amniocentesis. That age became "the" prompt for genetic counseling. Much has been learned since then, and this is discussed in an article published in the Journal of the American Medical Association (JAMA) by Berkowitz et al. (Challenging the Strategy of Maternal Age-Based Prenatal GC, JAMA, 2006; Vol. 295; pp. 1446-1448).
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