Stretch Marks Are Never Good Stretch marks are not only unsightly, but women with this disorder, appear to be at increased risk for pelvic prolapse.
Getting Streptavidin To Go It Alone Research describes a popular system for protein labelling and modification to reduce the risk of unwanted cross-reactions.
The RNAi Revolution Marches On Scientists have taken an important step towards a new class of drug treatment that harnesses the RNA interference pathway.
Early Sign Of Alzheimer's Scientists reveal what could be one of the earliest molecular seeds of Alzheimer's disease.
Down's Syndrome Scientists make an important step towards determining how a 1.5-fold increase in gene dosage on chromosome 21 triggers the various developmental problems associated with Down's syndrome.
Alzheimer's Protein Player Exposed Researchers reveal how an enzyme called Pin1 plays a part in the pathogenesis of Alzheimer's disease.
A tale of a tail: to condense or not to condense....Ac is the question. It has long been known that acetylation of core histone tails is fundamental in the organisation of a transcriptionally permissive chromatin structure. New work shows how this small modification has macromolecular effects.
Partners In Crime Scientists have defined the detailed architecture of an enzyme crucial for the replication of two major human viruses.
Protein Teamwork Underlies Skeleton Researchers show how mutations in two different proteins can cause osteopetrosis, a rare congenital human disorder.
It's All In The Expression Changes in the expression level of certain genes may underlie some of the fundamental differences between humans and chimpanzees.
Coral Compound Blocks Viruses A small molecule has been discovered in coral that can be used to block the replication of certain viruses.
Natalizumab: Proceed with Caution Natalizumab used to treat multiple sclerosis, Crohn’s disease, and rheumatoid arthritis may or may not be linked to progressive multifocal leukoencephalopathy.
Childhood Depression Linked To Asthma And Obesity The authors investigated how many of the participants suffered from childhood depression and compared this with those who later became obese or developed asthma.
Gene Regulation And Depression Mice subjected to stress caused by the presence of an aggressive intruder, repress the gene that produces a growth factor called brain derived neurotrophic factor (BDNF).
Hunger For Memories The hunger-signaling gut hormone ghrelin can increase the number of nerve connections in a region of the brain crucial for the formation of new memories.
A 'Retro' Alternative For Immunology Researchers A simple strategy for creating mice that express multiple foreign proteins could help some scientists to study essential processes of immune development without the trouble of transgenics.
Bottom's Up To Gene Control Study shows one way that may be possible for designing and building new biological parts and systems from their individual components.
Non-Viral Gene Delivery: Stretching Is The Point The authors discuss how matrix-based approaches provide a solid foundation for the application of gene therapies for tissue regeneration and engineering.