home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

Mouse Model of Hepatitis C Infection One Step Closer

  February, 18 2009 7:52
your information resource in human molecular genetics

A therapeutically useful mouse model of hepatitis C virus (HCV) infection is one step closer with the discovery of a key protein needed for mouse cell infection.

The human occludin protein needs to be present for HCV to enter mouse cells, Charles Rice and colleagues report in Nature. This makes it the fourth and final essential component of the HCV cell-entry receptor.

HCV is a leading cause of liver disease worldwide, but therapeutic design and vaccine development have been hampered by the lack of a suitable small animal model - until now, mouse cells could not be infected with HCV.


Charles Rice (The Rockefeller University, New York, NY, USA)
E-mail: ricec@rockefeller.edu

Abstract available online.

(C) Nature press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.