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Evolution of methodologies for high-throughput genetic analysis has led to a change in paradigms: many researchers are spending more time in the analysis of very large datasets than in their generation. In recent years, several hundred in silico tools have been developed in order to support and automate the design and analysis of a variety of molecular approaches. Almost all of them are freely available on the Internet or are supported as open source projects.
A team in Canada has developed the Bioinformatics Links Directory, a complete collection of available in silico tools. It provides information about over 1200 tools (including links to the web addresses and to the respective references and brief descriptions for each tool). It is organized in different categories, such as Expression, DNA, Protein or RNA); there is also a search option to find specific tools. Some tools for several areas, such as microarray data or protein domains, are highly represented; consistent with their development and growth in last years. The Bioinformatics Links Directory is available online
Message posted by: Diego Forero
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