home   genetic news   bioinformatics   biotechnology   literature   journals   ethics   positions   events   sitemap
  HUM-MOLGEN -> Genetic News | search  

DNA Braces For Change

  February, 7 2008 10:18
your information resource in human molecular genetics

Dynamic DNA nanostructures can change their shape in response to specific molecular signals, according to a study to be published online in Nature Nanotechnology. The ability to rearrange well-defined 3D assemblies may have implications for the fabrication of nanomechanical devices or for drug-release applications.

Although DNA is best known as the molecule that encodes genetic information, it is also an incredibly versatile building material at the nanoscale. Many examples of DNA nanostructures have been reported, but potential uses are somewhat limited by their static nature.

Andrew Turberfield and co-workers have made DNA tetrahedra containing edges that can be expanded and contracted to change the overall shape of the assembly. They constructed a nanodevice that can be cycled through four different states by incorporating two different reconfigurable edges in a single DNA tetrahedron. In principle, this process could be used to produce useful motion by integrating the tetrahedra into larger structures.

Author contact:

Andrew Turberfield (University of Oxford, UK)
E-mail: a.turberfield1@physics.ox.ac.uk

Abstract available online.

(C) Nature Nanotechnology press release.

Message posted by: Trevor M. D'Souza

print this article mail this article
Latest News
Variants Associated with Pediatric Allergic Disorder

Mutations in PHF6 Found in T-Cell Leukemia

Genetic Risk Variant for Urinary Bladder Cancer

Antibody Has Therapeutic Effect on Mice with ALS

Regulating P53 Activity in Cancer Cells

Anti-RNA Therapy Counters Breast Cancer Spread

Mitochondrial DNA Diversity

The Power of RNA Sequencing

‘Pro-Ageing' Therapy for Cancer?

Niche Genetics Influence Leukaemia

Molecular Biology: Clinical Promise for RNA Interference

Chemoprevention Cocktail for Colon Cancer

more news ...

Generated by News Editor 2.0 by Kai Garlipp
WWW: Kai Garlipp, Frank S. Zollmann.
7.0 © 1995-2023 HUM-MOLGEN. All rights reserved. Liability, Copyright and Imprint.