your information resource in human molecular genetics
2008-02-21
Treatment-Resistant Depression Might Be In The Genes Variation in the gene coding for the potassium channel TREK1 may explain why some patients with depression do not respond to commonly prescribed antidepressants.
Reversing Impaired Brain Function In Diabetes An increase in the stress hormone corticosterone that is caused by diabetes leads to deficits in the birth of new neurons and memory formation in rodents.
DNA Proves Its Potential The electrical conductivity of an individual DNA molecule can be measured by wiring it into a nanoscale circuit.
How HIV Ravages Gut Immune Cells The specific interaction between HIV and gut-associated immune cells, which may promote the depletion of cells and the virus' devastating attack on the immune system, is reported.
Genome-Wide View Of Prostate Cancer Risk At least ten newly identified genetic variants are associated with increased susceptibility to prostate cancer, according to three studies to be published online.
Renewable Cell Therapy For Diabetes Inches Closer Researchers have converted human embryonic stem (ES) cells into cells that release insulin in response to glucose and alleviate a diabetes-like condition in mice.
BRCA2 And Resistance To Therapy Scientists have gained new insight into how changes in BRCA2 can affect a cancer's resistance to therapy.
Defining An Anti-HIV Protein Understanding the structure of proteins involved in inhibiting HIV-1 infection could help in the battle against the disease.
Sugars Regulate Insulin Signalling An enzyme known to attach sugar to proteins in cells is revealed to have a role in insulin resistance in mice.
Leukaemia Relapses Linked To DNA Repair Problems Scientists have shown a link between acute myeloid leukaemia (AML), an aggressive cancer of the blood, and mutant genes in the DNA mismatch repair pathway.
DNA Braces For Change Dynamic DNA nanostructures can change their shape in response to specific molecular signals.
Amyloid Inhibitors Are Aggregates Too A new understanding of the way protein inhibitors work may have major implications in the development of drugs for Alzheimer's and other neurodegenerative diseases.
TBK1 Is Doubly Important Research demonstrates how DNA vaccines may induce adaptive immune responses.
The Plaque To Dementia Recent questions as to the role of amyloid plaques in the brains of patients with Alzheimer's disease are addressed.
Circadian Rhythms The release of blood stem cells into the bloodstream is regulated by circadian rhythms.
DNA Blueprint For Crystallization Two papers describe the programming of encodable interactions between nanoscale building blocks achieved by exploiting the recognition capabilities of DNA base pairing to direct assembly.
Sugar Rush To Protect The Heart Research uncovers an emergency strategy that the heart muscle uses to protect itself under such circumstances - enlisting molecules that help to keep it supplied with vital energy.
New Cells' Effect On Learning The deletion of a protein required for the proliferation of adult neural stem cells in mice appears to affect spatial learning and memory.