Levels of a type of adult stem cell in the bloodstream may indicate a person's risk of developing cardiovascular disease, according to a study supported by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health in Bethesda, MD.
The study looked at the blood level of endothelial progenitor cells, which are made in the bone marrow and may help the body repair damage to blood vessels. Scientists from NHLBI and Emory University Hospital in Atlanta, GA, found that cardiovascular disease risk was higher in persons with fewer endothelial progenitor cells. The cells of those at higher risk also aged faster than those at lower risk, as determined by the Framingham Heart Study risk factor score, a standard measurement of cardiovascular risk. Additionally, the study found that blood vessels were much less likely to dilate and relax appropriately in persons with low levels of the cells.
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