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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - January 25, 2007
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Thu, 25 Jan 2007 13:57:41 +0100

__________________________________________________________________________

   BioProcess International - European Conference and Exhibition
   Paris, France - 23-26 April 2007

   IBC's 3rd European BPI Conference and Exhibition is the premier event
   to attend in 2007 for a comprehensive update on operational strategies,
   technologies, regulatory changes, manufacturing production, and process
   development.	-> http://www.bpi-eu.com/
__________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - January 25, 2007 - http://hum-molgen.org


Genetic News
by T.M. D'Souza, S. Chandler, T. Dalaya, R. Kimmel, K. Markey, J. Mill,
La Merie S.L, R. Nemade, F.S. Zollmann
http://hum-molgen.org/NewsGen

- Anticancer Activity Of An Adenoviral Vector Expressing Short Hairpin
   RNA Against BK Virus T-ag
    Study indicates that siRNAs delivery via a viral vector have a
    potential usefulness as in vivo anticancer tool against viral and
    cellular oncogenes.
    http://hum-molgen.org/NewsGen/01-2007/000051.html

- Mapping Of Angiogenic Markers For Targeting Of Vectors To Tumor
   Vascular Endothelial Cells
    Study shows that a single administration of the AdfVII/IgG1Fc vector
    destroys the peripheral but not the central vasculature of a tumor
    spheroid.
    http://hum-molgen.org/NewsGen/01-2007/000050.html

- Gene Therapy Targeting To Tumor Endothelium
    In this review the authors assess the challenges faced and the
    vectors that may be suitable for gene delivery to exploit candidate
    targets.
    http://hum-molgen.org/NewsGen/01-2007/000049.html

- Methods For The Selection Of Tagging SNPs: A Comparison Of Tagging
   Efficiency And Performance
    This work demonstrates that when tagging single nucleotide
    polymorphisms (tSNPs)-based association studies are undertaken, the
    choice of method for selecting tSNPs requires careful consideration.
    http://hum-molgen.org/NewsGen/01-2007/000048.html

- Replication Of Reported Linkages For Dyslexia And Spelling And
   Suggestive Evidence For Novel Regions On Chromosomes 4 And 17
    Sceintists report the first genome-wide linkage analysis for reading
    and spelling in a sample of 403 families of twins, aged between 12
    and 25 years taken from the normal population and unselected for
    reading ability.
    http://hum-molgen.org/NewsGen/01-2007/000046.html

- Neurofibromatosis
    Positron emission tomography has demonstrated that sophisticated
    imaging techniques have a role in diagnosing complex problems like
    malignant peripheral nerve sheath tumours.
    http://hum-molgen.org/NewsGen/01-2007/000045.html

- Association Of PDCD1 Polymorphisms With Childhood-Onset Systemic Lupus
   Erythematosus
    The aim of this study was to investigate the association of the PDCD1
    gene polymorphisms and haplotypes with susceptibility to
    childhood-onset systemic lupus erythematosu in a Mexican population.
    http://hum-molgen.org/NewsGen/01-2007/000044.html

- Partial Duplications Of The MSH2 And MLH1 Genes In Hereditary
   Nonpolyposis Colorectal Cancer
    The contribution of genomic duplications of MSH2 and MLH1 genes to
    hereditary nonpolyposis colorectal cancer.
    http://hum-molgen.org/NewsGen/01-2007/000043.html

- Multiple Mutations Responsible For Frequent Genetic Diseases In
   Isolated Populations
    A selective advantage may explain most of the observations of more
    than one mutation in either one or several genes causing high
    frequency of an autosomal recessive disease.
    http://hum-molgen.org/NewsGen/01-2007/000042.html

- Genetic Screening For Autosomal Recessive Nonsyndromic Mental
   Retardation In An Isolated Population In Israel
    First example of the establishment of a large-scale genetic screening
    program for autosomal recessive Nonsyndromic Mental Retardation.
    http://hum-molgen.org/NewsGen/01-2007/000041.html

- Population Differences In Gene Expression
    Study reveals a significant ethnic variation in gene expression.
    http://hum-molgen.org/NewsGen/01-2007/000039.html

- Genetic Risk Factor For Stroke Found
    Individuals with a particular variant of the gene PRKCH have a 40%
    increased risk of cerebral infarction, the most common type of
    stroke.
    http://hum-molgen.org/NewsGen/01-2007/000038.html

- A New Source Of Stem Cells
    Amniotic fluid contains stem cells that can be coaxed towards
    becoming various cell types that might be useful in regenerative
    medicine.
    http://hum-molgen.org/NewsGen/01-2007/000037.html

- Enzyme Double Act Evades Drug Therapy
    New study may aid the design of more effective cancer therapies.
    http://hum-molgen.org/NewsGen/01-2007/000036.html

- Inhalant Abuse: 'Sniffing' Toluene For A High
    Toluene, a commonly abused toxic compound, is shown to stimulate
    dopamine release in specific regions of the rat brain known as drug
    reward pathways.
    http://hum-molgen.org/NewsGen/01-2007/000035.html

- African Chromosomes In Indigenous British
    A globally rare Y chromosome type described previously in only a few
    West African individuals has been found in a British male.
    http://hum-molgen.org/NewsGen/01-2007/000034.html

- Fetal Alcohol Syndrome: Are Cholesterol Supplements The Answer?
    Cholesterol supplementation prevents fetal alcohol spectrum defects
    (FASD) in alcohol-exposed zebrafish embryos.
    http://hum-molgen.org/NewsGen/01-2007/000033.html

- Scientists Find A Tunnel That Transfers Lipids
    Scientists have determined the structure of CETP, the protein that
    transfers lipids in the blood from 'good' to 'bad' cholesterol.
    http://hum-molgen.org/NewsGen/01-2007/000032.html

- For Goodness Sake
    The detection of 'agency', the presence of an active participant in a
    situation, involves a brain region that is more active in altruistic
    people.
    http://hum-molgen.org/NewsGen/01-2007/000031.html

- Getting Things Into Cells With The Aid Of Small Molecules
    Small molecules can be linked to much larger cargoes and deliver them
    into a variety of cell types.
    http://hum-molgen.org/NewsGen/01-2007/000030.html

- Maintaining Immune Regulation
    Constant expression of a single protein, Foxp3, is essential to
    maintain the identity and character of regulatory T (Treg) cells.
    http://hum-molgen.org/NewsGen/01-2007/000029.html

- Sizing Up Stem Cells
    A gene called latexin has a significant effect on the blood stem cell
    population in young mice.
    http://hum-molgen.org/NewsGen/01-2007/000028.html

- Genetic Risk Factor For Alzheimer Dsease
    Individuals with particular variants of the gene SORL1 have a
    modestly elevated risk of late-onset Alzheimer disease.
    http://hum-molgen.org/NewsGen/01-2007/000027.html

- Cancer Cleared By p53 Restoration
    Certain types of cancer can be pushed into regression by reactivating
    the tumour suppressor gene p53.
    http://hum-molgen.org/NewsGen/01-2007/000026.html

- Non-Coding RNA Interferes With Transcription
    A non-coding RNA represses expression of a cell-cycle-regulated gene
    by directly interfering with the binding of transcription factors.
    http://hum-molgen.org/NewsGen/01-2007/000025.html

- Getting to the bottom of memory
    For the first time researchers investigate the molecular basis of
    memory in living mice
    http://hum-molgen.org/NewsGen/01-2007/000024.html

- Toward A Genetic Test For Parkinson's Disease
    A microarray screening of venous blood RNA identified a set of eight
    unaffiliated genes that, combined, had predictive power for
    Parkinson's disease and another gene that may shed light on disease
    progression.
    http://hum-molgen.org/NewsGen/01-2007/000023.html

- Genome of Trichomoniasis Responsible for Common Sexually Transmitted
   Infection Sequenced
    Trichomonas vaginalis parasite is responsible for common sexually
    transmitted diseases and has become more drug resistant recently.
    It's genome sequence can lead to treatments, diagnostics and possible
    vaccine strategy.
    http://hum-molgen.org/NewsGen/01-2007/000022.html

- Anti-HIV Preventive Regimen Improved Women's Response
    To prevent passing HIV on to her child, a mother's response to HIV
    treatment is improved if at least six months have passed since she
    received a single dose during labor.
    http://hum-molgen.org/NewsGen/01-2007/000021.html

- Maternal Smoking Can Cause Cleft Lip and Palate
    A fetus lacking both copies of the gene called GSTT1 is less likely
    to be able to detoxify mother's smoke from cigarette smoking leading
    to cleft lip and palate.
    http://hum-molgen.org/NewsGen/01-2007/000020.html

- Vaccine for H5N1 Avian Influenza Enters Human Clinical Trial
    The first human trial of a DNA vaccine designed to prevent H5N1 avian
    influenza infection began on December 21, 2006.
    http://hum-molgen.org/NewsGen/01-2007/000019.html

- The amyloid co-conspirator: second genetic risk for Alzheimers
    People with a variant of a specific gene have a slightly elevated
    rise in the incidence of late-onset Alzheimer's disease, Canadian and
    U.S. researchers said.
    http://hum-molgen.org/NewsGen/01-2007/000018.html

- Combination gene therapy gives lung cancer a double punch
    Combination gene therapy delivered in lipid-based nanoparticles
    drastically reduces the number and size of human non-small cell lung
    cancer tumors in mice
    http://hum-molgen.org/NewsGen/01-2007/000017.html

- The right balance drives the field of PPAR agonist R&D
    A strongly growing market of now more than US$ 6 bln in 2006 for only
    tow PPAR gamma agonists founds the basis for a heavily researched
    field of next generation mono, dual or triple PPAR agonists with
    fine-tuned subtype combinations
    http://hum-molgen.org/NewsGen/01-2007/000016.html

- Contact Genetic News editors
    WWW: http://hum-molgen.org/editors.html
    E-mail: news@hum-molgen.org


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http://hum-molgen.org/positions/

- Cell and Molecular Biology / Anatomy: Post-doctoral fellow
    W.K. Kellogg eye center, University of Michigan,, Ann Arbor, 48105,
    United States of America
    http://hum-molgen.org/positions/postdocs/2641.html

- Neurology / Neuroscience: Post-doctoral fellow
    TU Kaiserslautern, Kaiserslautern 67653 Germany
    http://hum-molgen.org/positions/postdocs/2640.html

- Neurology / Neuroscience: predoctoral fellow
    TU Kaiserslautern, Kaiserslautern 67653 Germany
    http://hum-molgen.org/positions/predoctoral/0567.html

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__________________________________________________________________________

   BioProcess International - European Conference and Exhibition
   Paris, France - 23-26 April 2007

   IBC's 3rd European BPI Conference and Exhibition is the premier event
   to attend in 2007 for a comprehensive update on operational strategies,
   technologies, regulatory changes, manufacturing production, and process
   development.	-> http://www.bpi-eu.com/
__________________________________________________________________________

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| INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
| HUM-MOLGEN - http://hum-molgen.org
| (C) 1994-2007





   
 
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