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To: list@hum-molgen.de
Subject: HUM-MOLGEN News Alert - April 19, 2007
From: FS Zollmann <zollmann@hum-molgen.de>
Date: Thu, 19 Apr 2007 13:58:26 +0200


__________________________________________________________________________


   European Biomarkers Summit, 4-5 September, 2007, Amsterdam, Netherlands

   Select Biosciences’ 2nd annual European Biomarkers Summit will be held
   in the colourful city of Amsterdam. We have assembled an excellent list
   of influential speakers, and will have many exhibitors from industry
   leaders taking part.

   http://www.selectbiosciences.com/conferences/EBS2007/index.aspx
__________________________________________________________________________


INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
HUM-MOLGEN News Alert - April 19, 2007 - http://hum-molgen.org


Genetic News
by T.M. D'Souza, S. Chandler, T. Dalaya, R. Kimmel, K. Markey, J. Mill,
La Merie S.L, R. Nemade, F.S. Zollmann
http://hum-molgen.org/NewsGen

- Lentiviral Vector Neutral Endopeptidase Gene Transfer Suppresses
  Prostate Cancer Tumor Growth (Abstract)
   Study demonstrates that lentiviral NEP gene transfer is a novel
   targeted strategy for the treatment of NEP-deficient PC.
   http://hum-molgen.org/NewsGen/04-2007/000022.html

- X-Chromosome Linked Inhibitor Of Apoptosis Protein Inhibits Muscle
  Proteolysis In Insulin-Deficient Mice (Abstract)
   The ability of XIAP to prevent the loss of muscle protein suggests
   that XIAP could be a therapeutic reagent for muscle atrophy in
   catabolic diseases X.
   http://hum-molgen.org/NewsGen/04-2007/000021.html

- Stable Gene Expression Occurs From A Minority Of Integrated
   HIV-1-Based Vectors: Transcriptional Silencing Is Present In The
   Majority (Abstract)
    Dae suggest that there are two forms of vector silencing: one
    occurring immediately after integration, and one occurring in the
    much longer term.
    http://hum-molgen.org/NewsGen/04-2007/000020.html

- Increasing Bad Cholesterol Levels
    Study suggests how the gene PCSK9 maintains cholesterol balance in
    the body.
    http://hum-molgen.org/NewsGen/04-2007/000019.html

- Astrocytes Kill Neurons In ALS
    Two papers report that astrocytes carrying a mutated version of a
    protein that causes ALS, also known as Lou Gehrig's disease, are
    responsible for the death of motor neurons.
    http://hum-molgen.org/NewsGen/04-2007/000018.html

- Stabilization Contra Retardation
    Paper explores the mechanisms underlying fragile X syndrome -- the
    most common inherited form of mental retardation.
    http://hum-molgen.org/NewsGen/04-2007/000017.html

- How One's Own DNA Can Cause Autoimmunity
    Study may shed light on the cause of immune activation associated
    with systemic lupus erythematosus (SLE) -- the second most common
    autoimmune disease in humans.
    http://hum-molgen.org/NewsGen/04-2007/000016.html

- Mutation Leads To Male Infertility
    Paper reports that a mutation in a gene called AURKC (Aurora Kinase
    C) has been identified in 14 infertile men of North African descent.
    http://hum-molgen.org/NewsGen/04-2007/000015.html

- Genetic Susceptibility To Crohn Disease
    A genome-wide assessment of genetic variation in individuals with
    Crohn disease has identified seven genes or regions that are
    associated with elevated risk of the disease.
    http://hum-molgen.org/NewsGen/04-2007/000014.html

- Amplification Of Estrogen Receptor Gene In Breast Cancer
    Study suggests that nearly two-thirds of breast tumors have extra
    copies of the gene encoding one form of the estrogen receptor ESR1.
    http://hum-molgen.org/NewsGen/04-2007/000013.html

- Genes Linked To Chemotherapy Response
    Scientists have identified a number of genes in lung cancer cells
    which, when downregulated, make the cancer cells especially
    vulnerable to a type of chemotherapy.
    http://hum-molgen.org/NewsGen/04-2007/000012.html

- Genes Set Scene For Metastasis
    Biologists have identified a set of genes expressed in human breast
    cancer cells that work together to remodel the vasculature at the
    site of the primary tumour and that also promote the spread of cancer
    to the lungs.
    http://hum-molgen.org/NewsGen/04-2007/000011.html

- Scientists identify a candidate gene for osteoporosis
    Gene may underlie differences between African Americans and
    Caucasians
    http://hum-molgen.org/NewsGen/04-2007/000010.html

- Contact Genetic News editors
    WWW: http://hum-molgen.org/editors.html
    E-mail: news@hum-molgen.org


Biomedical Positions
http://hum-molgen.org/positions/

- Call for Assistant News Editors
    Support the HUM-MOLGEN concept actively!
    http://hum-molgen.org/NewsGen/03-2007/000037.html

- Cell and Molecular Biology / Anatomy: Postdoctoral Fellow
    Max-Delbrück-Centrum for Molecular Medicine Berlin-Buch, 13125,
    Berlin, Germany
    http://hum-molgen.org/positions/postdocs/2649.html

- Genetics: PhD student
    TELETHON INSTITUTE OF GENETICS AND MEDICINE, NAPOLI, 80131, Italy
    http://hum-molgen.org/positions/predoctoral/0572.html

- Write a position announcement
    http://hum-molgen.org/flyer/positions.pdf
    1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register
    2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login


DIAGnostics - Clinical Research (professional requests)
http://hum-molgen.org/clinical-research/

- Post diagnostic request / call for collaboration
    http://hum-molgen.org/diagnostic-posting or
    contact admin@hum-molgen.org


Biotechnical requests and sources
http://hum-molgen.org/biotechnology

- Post request or source
   http://hum-molgen.org/biotechnical-request-posting


Literature
http://hum-molgen.org/literature/


Events in bioscience and medicine
http://hum-molgen.org/meetings/

- Early Steps of the Virus Life Cycle: Molecular and Cellular Insights
    Institut Pasteur de Paris, Institut Pasteur, Paris, France
    October 4-5, 2007
    http://hum-molgen.org/meetings/meetings/3255.html

- GENETICS AND MECHANISMS OF SUSCEPTIBILITY TO INFECTIOUS DISEASES
    Institut Pasteur de Paris, Paris, France
    November 21-24, 2007
    http://hum-molgen.org/meetings/meetings/3254.html

- FROM MOLECULES TO COGNITION: A TRIBUTE TO JEAN-PIERRE CHANGEUX
    Institut Pasteur, Paris
    September 17-19, 2007
    http://hum-molgen.org/meetings/meetings/3253.html

- The Biology of Vibrios
    Institut Pasteur, Paris
    Nov. 28- Dec 1, 2007
    http://hum-molgen.org/meetings/meetings/3252.html

- Rosenön Meeting 2007: DMPK and PK/PD from Lead to Product - Recent
   Developments and Trends in an Expanding Science
    The Swedish Academy of Pharmaceutical Sciences, Rosenön, Stockholm,
    Sweden
    September 20-22, 2007
    http://hum-molgen.org/meetings/meetings/3251.html

- Target Product Profiles as Strategic Development Process Tools
    Drug Information Association, Online
    May 9 2007
    http://hum-molgen.org/meetings/courses/0943.html

- Clinical Statistics for NonStatisticians
    Drug Information Association, Renaissance Penta Vienna Hotel,
    Ungargasse 60, Vienna, Austria
    June 14 2007
    http://hum-molgen.org/meetings/courses/0942.html

- Introduction to Project Management for the Clinical Data Management
   Professional
    Drug Information Association, Online
    Apr 25 2007
    http://hum-molgen.org/meetings/courses/0941.html

- Outsourcing for the Therapeutics Industry
    The Center for Professional Innovation & Education, Costa Mesa, CA
    June 14 & 15, 2007
    http://hum-molgen.org/meetings/courses/0940.html

- Introduction to Effective Medical Writing
    The Center for Professional Innovation & Education, Costa Mesa, CA
    June 14 & 15, 2007
    http://hum-molgen.org/meetings/courses/0939.html

- Current Good laboratory Practices & Current Good Manufacturing
   Practices – A Basic Primer
    The Center for Professional Innovation & Education, Costa Mesa, CA
    June 13-15, 2007
    http://hum-molgen.org/meetings/courses/0938.html

- Generic Drug Approvals – Preparing an ANDA for First-Cycle Approval
    The Center for Professional Innovation & Education, Costa Mesa, CA
    June 13-15, 2007
    http://hum-molgen.org/meetings/courses/0937.html

- Moving from Discovery Into Development
    The Center for Professional Innovation & Education, Costa Mesa, CA
    June 13-15, 2007
    http://hum-molgen.org/meetings/courses/0936.html

- QA/QC Strategy for Biopharmaceuticals and Biologics
    The Center for Professional Innovation & Education, Malvern, PA
    June 6-8, 2007
    http://hum-molgen.org/meetings/courses/0935.html

- The Drug Development Process - From Development to Approval
    The Center for Professional Innovation & Education, Costa Mesa, CA
    June 6-8, 2007
    http://hum-molgen.org/meetings/courses/0934.html

- The CTD: Recommended Format and Implementation of the ICH Common
   Technical Document for Marketing Application Submissions
    The Center for Professional Innovation & Education, Malvern, PA
    June 4 & 5, 2007
    http://hum-molgen.org/meetings/courses/0933.html

- Software Development for Medical Device Professionals
    The Center for Professional Innovation & Education, Malvern, PA
    June 4 & 5, 2007
    http://hum-molgen.org/meetings/courses/0932.html

- Drug Master Files (DMFs) - Understanding and Meeting Your Regulatory
   and Processing Responsibilities
    The Center for Professional Innovation & Education, Malvern, PA
    May 24 & 25, 2007
    http://hum-molgen.org/meetings/courses/0931.html

- Stability Programs for Product Shelf Life – From Development to
   Approval
    The Center for Professional Innovation & Education, Malvern, PA
    May 23 & 24, 2007
    http://hum-molgen.org/meetings/courses/0930.html

- Introduction to Statistical Analysis of Laboratory Data
    The Center for Professional Innovation & Education, Malvern, PA
    May 21 & 22, 2007
    http://hum-molgen.org/meetings/courses/0929.html

- Root Cause Analysis for CAPA
    The Center for Professional Innovation & Education, Dublin, Ireland
    May 21-23, 2007
    http://hum-molgen.org/meetings/courses/0928.html

- Pharmaceutical, Biopharmaceutical and Biologics Quality Control
   Laboratories: A Regulatory Compliance Primer
    The Center for Professional Innovation & Education, Malvern, PA
    May 21 & 22, 2007
    http://hum-molgen.org/meetings/courses/0927.html

- ADME, PK/TK, and Drug Metabolism in Drug Discovery and Development
    The Center for Professional Innovation & Education, Costa Mesa, CA
    May 17 & 18, 2007
    http://hum-molgen.org/meetings/courses/0926.html

- Effective Quality Assurance Auditing for FDA Regulated Industries
    The Center for Professional Innovation & Education, Dublin, Ireland
    May 17 & 18, 2007
    http://hum-molgen.org/meetings/courses/0925.html

- cGMP for Quality Assurance and Quality Control of Pharmaceuticals,
   Biopharmaceuticals and Biologics
    The Center for Professional Innovation & Education, Malvern, PA
    May 16-18, 2007
    http://hum-molgen.org/meetings/courses/0924.html

- Stability Testing of Proteins, Peptides & Other Biomolecules
    The Center for Professional Innovation & Education, Malvern, PA
    May 14 & 15, 2007
    http://hum-molgen.org/meetings/courses/0923.html

- Reporting Failure Investigation and Process Deviations
    The Center for Professional Innovation & Education, Dublin, Ireland
    May 14-16, 2007
    http://hum-molgen.org/meetings/courses/0922.html

- Design Control for Medical Device Professionals
    The Center for Professional Innovation & Education, Dublin, Ireland
    May 14 & 15, 2007
    http://hum-molgen.org/meetings/courses/0921.html

- Quality System Regulation for the Medical Device & Biotech Industries
    The Center for Professional Innovation & Education, Costa Mesa, CA
    May 10 & 11, 2007
    http://hum-molgen.org/meetings/courses/0920.html

- Analytical Method Validation for Pharmaceutical, Biopharmaceutical,
   and Biologics Quality Control
    The Center for Professional Innovation & Education, Costa Mesa, CA
    May 9 & 10, 2007
    http://hum-molgen.org/meetings/courses/0919.html

- Biostatistics for Non-Statisticians
    The Center for Professional Innovation & Education, Costa Mesa, CA
    May 7-9, 2007
    http://hum-molgen.org/meetings/courses/0918.html

- Process Validation for Medical Devices
    The Center for Professional Innovation & Education, Malvern, PA
    May 7-9, 2007
    http://hum-molgen.org/meetings/courses/0917.html

- Stability Programs for Product Shelf Life – From Development to
   Approval
    The Center for Professional Innovation & Education, Costa Mesa, CA
    May 7 & 8, 2007
    http://hum-molgen.org/meetings/courses/0916.html

- Project Management for the Phase 3 and LCM (Life Cycle Management)
    The Center for Professional Innovation & Education (CfPIE), Malvern,
    PA
    May 1 & 2, 2007
    http://hum-molgen.org/meetings/courses/0915.html

- Post event (free)
   http://hum-molgen.de/cgi-bin/meetings.pl?login


Registry of Biomedical Companies (1427 active entries)
http://hum-molgen.org/companies/


Mailing List Administration (Join or leave the list)
http://hum-molgen.org/subscribe-na/


Feedback
contact admin@hum-molgen.org


Advertise at HUM-MOLGEN
http://hum-molgen.org/flyer/advertise.pdf
contact FS Zollmann (dialogue@hum-molgen.org)

__________________________________________________________________________

   European Biomarkers Summit, 4-5 September, 2007, Amsterdam, Netherlands

   Select Biosciences’ 2nd annual European Biomarkers Summit will be held
   in the colourful city of Amsterdam. We have assembled an excellent list
   of influential speakers, and will have many exhibitors from industry
   leaders taking part.

   The provisional agenda and registration details, including early bird,
   are online.

   Register for this conference, and you will also have access to the
   co-located Proteomics Europe meeting.

   http://www.selectbiosciences.com/conferences/EBS2007/index.aspx
__________________________________________________________________________

--
| INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS
| HUM-MOLGEN - http://hum-molgen.org
| (C) 1994-2007





   
 
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