HUM-MOLGEN archive: HUM-MOLGEN News Alert

__________________________________________________________________________ RNAi Europe - Conference & Exhibition 28-29 September 2006, Prague, Czech Republic => http://hum-molgen.org/promotion-RNAi __________________________________________________________________________ INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS HUM-MOLGEN News Alert - May 24, 2006 - http://hum-molgen.org Genetic News by T.M. D'Souza, S. Chandler, T. Dalaya, K. Markey, J. Mill, La Merie S.L, R. Nemade, D. Sharma, F.S. Zollmann http://hum-molgen.org/NewsGen - Inducible Regulation Of Runx2-Stimulated Osteogenesis Researchers describe a retroviral system to deliver the Runx2 osteoblastic transcription factor. http://hum-molgen.org/NewsGen/05-2006/msg40.html - Mosaic Vectors For Efficient Vector Purification And Targeting To Vascular Endothelial Cells Adeno-associated virus (AAV) 1 has shown the most promise among the AAV vectors for the transduction of vascular endothelial cells. http://hum-molgen.org/NewsGen/05-2006/msg39.html - RNAi Therapeutics: Can siRNAs Conquer SARS? Report on a new approach to coping with emerging infectious diseases, that uses small interfering (si)RNAs. http://hum-molgen.org/NewsGen/05-2006/msg38.html - Regeneration Of Injured Optic Nerve A treatment applied three days after optic nerve injury greatly improves regeneration. http://hum-molgen.org/NewsGen/05-2006/msg37.html - New Techniques For Chromosomal Damage Control Two articles describe tools for the detection of large-scale structural rearrangements in individual chromosomes. http://hum-molgen.org/NewsGen/05-2006/msg36.html - Gene Variant Associated With Type 1 Diabetes A new gene variant associated with risk of type 1 diabetes is reported. http://hum-molgen.org/NewsGen/05-2006/msg35.html - Mothballs Link Cell Death And Cancer Components of the humble mothball are carcinogens because they block cell suicide. http://hum-molgen.org/NewsGen/05-2006/msg34.html - SUMO Switches Metastasis On And Off New players in the process of metastasis of cancer cells are described. http://hum-molgen.org/NewsGen/05-2006/msg33.html - Immune Molecule Fuels Tumours A molecule central to chronic autoimmune diseases also promotes the incidence and growth of tumours. http://hum-molgen.org/NewsGen/05-2006/msg32.html - Chromosome 1 Completes The Set Report on the finished DNA sequence of human chromosome 1. http://hum-molgen.org/NewsGen/05-2006/msg31.html - Novel Antibiotic Fights Hospital Killers Team of researchers discovers a potent natural antibiotic that kills many Gram-positive bacteria. http://hum-molgen.org/NewsGen/05-2006/msg30.html - A New Signal For Axon Regeneration Is Discovered Oncomodulin, released from macrophages, stimulates axon regeneration as part of the response to optic nerve injury. http://hum-molgen.org/NewsGen/05-2006/msg29.html - The next generation of interferons needs improvement in efficacy and safety The interferon alpha market is smaller than the interferon beta market, but is characterized by far more products and R&D projects. http://hum-molgen.org/NewsGen/05-2006/msg28.html - Tumor Stem Cells Turn Out to be Good Models for Brain Tumor Research Glioblastoma tumor stem cell lines offer a powerful new tool for research and treatment. http://hum-molgen.org/NewsGen/05-2006/msg27.html - Prozac's Target Revealed Neural stem cells provide information about how cells become reactive to Prozac (fluoxetine). http://hum-molgen.org/NewsGen/05-2006/msg25.html - A Loose Fit May Be The Best Bet In Drug Design Common wisdom challenged as loosely connecting ligands at receptor sites lead to better signalling. http://hum-molgen.org/NewsGen/05-2006/msg26.html - Total-Genome Analysis of BRCA1/2-Related Invasive Carcinomas of the Breast Identifies Tumor Stroma as Potential Landscaper for Neoplastic Initiation Authors postulate that such a genetically unstable stroma might facilitate a microenvironment that may subsequently lead to neoplastic transformation. http://hum-molgen.org/NewsGen/05-2006/msg24.html - ELMOD2 Is A Candidate Gene For Familial Idiopathic Pulmonary Fibrosis Research suggests ELMOD2 as a novel candidate gene for susceptibility in familial IPF. http://hum-molgen.org/NewsGen/05-2006/msg23.html - Human Genomic Deletions Mediated By Recombination Between Alu Elements Scientists compare the reference human and chimpanzee genomes to determine the magnitude of this recombination process in the human lineage. http://hum-molgen.org/NewsGen/05-2006/msg21.html - Promoter Mutations That Increase Amyloid Precursor-Protein Expression Are Associated with Alzheimer Disease The present study provides evidence that Amyloid Precursor-Protein (APP)-promoter mutations that significantly increase APP expression levels are associated with Alzheimer disease. http://hum-molgen.org/NewsGen/05-2006/msg20.html - Diabetes Gene At Root Of Wider Syndrome Study shows that some of the 'Gain of function' gene mutations associated with neonatal diabetes mutations can cause a syndrome that can include developmental delay, epilepsy and muscle weakness. http://hum-molgen.org/NewsGen/05-2006/msg19.html - Old Drug, New Target Scientists have identified a new target for an old drug that has been used to treat tuberculosis for over 50 years http://hum-molgen.org/NewsGen/05-2006/msg18.html - Better Digs Benefit Behavior: New Neurons Not Required A new study fails to find a causal relationship between behavioral improvements and increased neurogenesis in adult mice. http://hum-molgen.org/NewsGen/05-2006/msg17.html - Sensing Bacterial Infection New information on the complex interplay between host cells and bacteria during infection is reported. http://hum-molgen.org/NewsGen/05-2006/msg16.html - Common Genetic Variant Associated With Prostate Cancer A common genetic marker that is found more frequently in men with prostate cancer than those without is reported in a study. http://hum-molgen.org/NewsGen/05-2006/msg15.html - Nuclear Protein Controls Virus Invasion A protein in the cell's nuclear membrane regulates the ability of the HIV virus to invade human cells. http://hum-molgen.org/NewsGen/05-2006/msg14.html - Parkinson's Gene Cripples Mitochondria Two teams of scientists reveal that a mutant protein implicated in inherited Parkinson's disease disables the cell's mitochondria. http://hum-molgen.org/NewsGen/05-2006/msg13.html - LOX Stops The Spread Scientists identify a protein vital for metastasis that could be a new target for cancer therapies. http://hum-molgen.org/NewsGen/05-2006/msg12.html - Not Without Risk A gene-therapy treatment for a severe immune deficiency could contribute to the later development of T-cell lymphomas. http://hum-molgen.org/NewsGen/05-2006/msg11.html - Contact Genetic News editors WWW: http://hum-molgen.org/editors.html E-mail: news@hum-molgen.org DIAGnostics - Clinical Research (professional requests) http://hum-molgen.org/clinical-research/ - Post diagnostic request / call for collaboration http://hum-molgen.org/diagnostic-posting or contact admin@hum-molgen.org Biomedical Positions http://hum-molgen.org/positions/ - Cancer Research: PhD student University of Tuebingen, Tuebingen, 72076, Germany http://hum-molgen.org/positions/predoctoral/0559.html - Cancer Research: Postdoctoral Junior Group leader University of Tuebingen, Tuebingen, 72076, Germany http://hum-molgen.org/positions/postdocs/2617.html - Write a position announcement http://hum-molgen.org/flyer/positions.pdf 1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register 2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login Literature http://hum-molgen.org/literature/ Biotechnical requests and sources http://hum-molgen.org/biotechnology Events in bioscience and medicine http://hum-molgen.org/meetings/ - 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