HUM-MOLGEN archive: HUM-MOLGEN News Alert

__________________________________________________________________________ DRUG DISCOVERY TECHNOLOGY EUROPE 2006 Conference & Exhibition 13-16 March 2006 - London, UK http://hum-molgen.org/promotion-DDT __________________________________________________________________________ INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS HUM-MOLGEN News Alert - February 01, 2006 - http://hum-molgen.org Genetic News by T.M. D'Souza, S. Chandler, T. Dalaya, K. Markey, J. Mill, La Merie S.L, R. Nemade, D. Sharma, F.S. Zollmann http://hum-molgen.org/NewsGen - Vaccine Provides 100 Percent Protection Against Avian Flu Virus In Animal Study Protection of Mice and Poultry from Lethal H5N1 Avian Influenza Virus through Adenovirus-Based Immunization http://hum-molgen.org/NewsGen/01-2006/msg41.html - Master Genetic Switch Found For Chronic Pain Runx1 Determines Nociceptive Sensory Neuron Phenotype and Is Required for Thermal and Neuropathic Pain http://hum-molgen.org/NewsGen/01-2006/msg40.html - Researchers Identify Major Source Of Muscle Repair Cells Somitic origin of limb muscle satellite and side population cells http://hum-molgen.org/NewsGen/01-2006/msg39.html - The SERPINE2 Gene Is Associated with Chronic Obstructive Pulmonary Disease Study suggests that SERPINE2 is a Chronic Obstructive Pulmonary Disease (COPD)-susceptibility gene and is likely influenced by gene-by-smoking interaction. http://hum-molgen.org/NewsGen/01-2006/msg38.html - Mutations in ACY1, the Gene Encoding Aminoacylase 1, Cause a Novel Inborn Error of Metabolism Aminoacylase 1 (ACY1) mutations lead to functional ACY1 deficiency and excretion of N-acetylated amino acids. http://hum-molgen.org/NewsGen/01-2006/msg37.html - A Genome wide Search Finds Major Susceptibility Loci For Gallbladder Disease On Chromosome 1 In Mexican Americans Research presents significant evidence of major genetic determinants of symptomatic GBD on chromosome 1p in Mexican Americans. http://hum-molgen.org/NewsGen/01-2006/msg36.html - Modeling Stroke With Increased Precision Scientists have found a way to model different types of stroke with unprecedented precision by targeting individual rat blood vessels with controlled laser bursts. http://hum-molgen.org/NewsGen/01-2006/msg35.html - Fighting Legionnaires' Disease New research indicates how the immune system fights bacteria causing the severe pneumonia Legionnaires' disease. http://hum-molgen.org/NewsGen/01-2006/msg34.html - HIV Nef Damages Antibody Responses Report of a new mechanism by which human immunodeficiency virus (HIV) cripples immune responses in virus-infected AIDS patients. http://hum-molgen.org/NewsGen/01-2006/msg33.html - Genetics Of Earwax Determination Research presents evidence of the genetic basis that determines whether human earwax (cerumen) is wet or dry. http://hum-molgen.org/NewsGen/01-2006/msg32.html - Stopping The Spiral Research findings have important implications for designing new proteins with improved properties, perhaps using left-handed amino acids. http://hum-molgen.org/NewsGen/01-2006/msg31.html - HIV-1 Infection Explained Scientists present an insight on the development of AIDS from HIV-1. http://hum-molgen.org/NewsGen/01-2006/msg30.html - Emerging diabetes drugs in early development The complexity of glucose metabolism and the number of cellular processes affected by diabetes provides ample space for new drug targets and for first-in-class molecules. http://hum-molgen.org/NewsGen/01-2006/msg29.html - RNA eye: A new player in anti-neovascular therapy The knockdown of VEGFR-1 with a modified siRNA shows remarkable efficacy in two mouse models of retinal angiogenesis associated with macular degeneration or diabetic retinopathy. http://hum-molgen.org/NewsGen/01-2006/msg28.html - Chimp/Human Antibodies Can Protect Against Smallpox Hybrid laboratory antibodies derived from chimpanzees and humans may provide a potentially safe and effective way to treat the serious complications that can occur following smallpox vaccination http://hum-molgen.org/NewsGen/01-2006/msg27.html - New Clinical Trial for Polycystic Kidney Disease Launched An opportunity to aid research http://hum-molgen.org/NewsGen/01-2006/msg26.html - Racial Differences in Teenage Nicotine Metabolism How nicotine is metabolized can influence which smoking cessation therapies to employ. http://hum-molgen.org/NewsGen/01-2006/msg25.html - High interest in inhibitors of the novel target sodium-dependent glucose (co-) transporter (SGLT) for therapy of type 2 diabetes A plethora of SGLT inhibitors in the patent literature and seven compounds in early clinical development indicate an abundance of interest in the therapeutic use of SGLT inhibitors for the treatment of type 2 diabetes. http://hum-molgen.org/NewsGen/01-2006/msg24.html - A Promising siRNA Microbicide for Sexually Transmitted Disease siRNA, targeting essential genes of the herpes simplex virus 2, offer durable protection that results in reduced morbidity in a preclinical model. http://hum-molgen.org/NewsGen/01-2006/msg23.html - Continuous Antiretroviral Therapy Superior to Episodic Therapy in HIV Treatment In the SMART clinical trial, it was found that patients receiving episodic therapy had twice the risk of disease progression. http://hum-molgen.org/NewsGen/01-2006/msg22.html - Study Links Alzheimer's Disease to Abnormal Cell Division A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. http://hum-molgen.org/NewsGen/01-2006/msg21.html - Genetic Protection Against HIV May Mean Higher Risk for West Nile Virus Lack of cell surface protein, CCR5, causes resistance against HIV, but may be needed to develop resistance against West Nile Virus. http://hum-molgen.org/NewsGen/01-2006/msg20.html - Soy Can Cause Reproductive Problems Genistein, a major component of soy, causes reproductive problems in laboratory mice. http://hum-molgen.org/NewsGen/01-2006/msg19.html - Contact Genetic News editors WWW: http://hum-molgen.org/editors.html E-mail: news@hum-molgen.org DIAGnostics - Clinical Research (professional requests) http://hum-molgen.org/clinical-research/ - Post diagnostic request / call for collaboration http://hum-molgen.org/diagnostic-posting or contact admin@hum-molgen.org Biotechnical requests and sources http://hum-molgen.org/biotechnology - 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