HUM-MOLGEN archive: HUM-MOLGEN News Alert

__________________________________________________________________________ RNAi Europe - Conference & Exhibition 28-29 September 2006, Prague, Czech Republic => http://hum-molgen.org/promotion-RNAi __________________________________________________________________________ INTERNATIONAL COMMUNICATION FORUM IN HUMAN MOLECULAR GENETICS HUM-MOLGEN News Alert - April 26, 2006 - http://hum-molgen.org Genetic News by T.M. D'Souza, S. Chandler, T. Dalaya, K. Markey, J. Mill, La Merie S.L, R. Nemade, D. Sharma, F.S. Zollmann http://hum-molgen.org/NewsGen - A Text-Mining Analysis Of The Human Phenome Scientists have used text mining to classify over 5000 human phenotypes contained in the Online Mendelian Inheritance in Man database. http://hum-molgen.org/NewsGen/04-2006/msg41.html - Schizophrenia Genetics: Uncovering Positional Candidate Genes Reports outlines the evidence supporting each of the proposed positional candidate genes. http://hum-molgen.org/NewsGen/04-2006/msg39.html - A Novel Mutation In JARID1C Gene Associated With Mental Retardation Report presents results obtained by screening the JARID1C gene in 24 mentally retarded males with history of at least two affected males. http://hum-molgen.org/NewsGen/04-2006/msg38.html - Neural Effects Of Cocaine Withdrawal Scientists describe a mechanism in the brain that may contribute to the cue-triggered drug seeking during abstinence. http://hum-molgen.org/NewsGen/04-2006/msg37.html - Teaching Transplant Tolerance Study explains how specific immune cells help to make transplanted donor tissue 'tolerable'. http://hum-molgen.org/NewsGen/04-2006/msg36.html - Natural Memory Natural killer (NK) cells, an important component of the immune system, can 'remember' prior exposure to foreign molecules. http://hum-molgen.org/NewsGen/04-2006/msg35.html - Genome Wide Profiling Of Chromatin Elements A new study reports the binding profile of proteins involved in organizing the structure of DNA in the Drosophila genome. http://hum-molgen.org/NewsGen/04-2006/msg34.html - New Link To Insulin Sensitization A new component involved in the regulation of an adipose-tissue hormone linked to insulin action. http://hum-molgen.org/NewsGen/04-2006/msg33.html - Better Detection To Tackle Bioterrorism Scientists have developed a test that is at least a thousand times more sensitive than the best current approaches for detecting in the field trace quantities of cholera and botulinum toxins. http://hum-molgen.org/NewsGen/04-2006/msg32.html - Stem Cells And Leukaemia Study shows that a signalling molecule known as phosphatase and tensin homologue, or PTEN,is crucial in keeping in balance the normal expansion of cell numbers in the bone marrow proliferation pathway. http://hum-molgen.org/NewsGen/04-2006/msg31.html - Regular Recycling Saves Lives Two research papers suggest that the process of protein degradation and clearance of cellular components may be more important in maintaining the nervous system and keeping neurodegeneration at bay than was previously understood. http://hum-molgen.org/NewsGen/04-2006/msg30.html - Keeping Stem Cells In Check A group of proteins has been shown to help hold the reins on embryonic stem (ES) cell differentiation. http://hum-molgen.org/NewsGen/04-2006/msg29.html - Metabolic Phenotype Predicts Drug Response European team proposes a new way to personalize drug therapy based on a patient's metabolic phenotype. http://hum-molgen.org/NewsGen/04-2006/msg28.html - Evading The Immune System To Deliver Viral Antibodies A virus that shows promise as a means of vaccine delivery of HIV-1 antigens could be altered to become effective in a larger portion of the population. http://hum-molgen.org/NewsGen/04-2006/msg27.html - Triggering Insulin Resistance Study identifies reactive oxygen species as key players in the development of insulin resistance. http://hum-molgen.org/NewsGen/04-2006/msg26.html - Identifying The Function Of p110-alpha AOP One form of the enzyme p110-alpha PI(3)K is vital for cell growth and metabolism. http://hum-molgen.org/NewsGen/04-2006/msg25.html - A Matter Of Taste An identical variability in taste sensitivity evolved independently in chimpanzees and humans. http://hum-molgen.org/NewsGen/04-2006/msg24.html - Minimal Cocktail For Growing Human Embryonic Stem Cells Established hESC cocktail contains only purified recombinant, chemically-synthesized, or purified human factors to support the cell growth http://hum-molgen.org/NewsGen/04-2006/msg23.html - Gene Variant Protects Against Type 2 Diabetes, Heart Disease, And Hypertriglyceridemia Identification of variant indicates that aP2 might play a similar role in humans as it does in mice http://hum-molgen.org/NewsGen/04-2006/msg22.html - Study Holds Promise For A New Approach To Drug Therapy Differential targeting of Gbetagamma-subunit signaling with small molecules http://hum-molgen.org/NewsGen/04-2006/msg21.html - New Mechanism for Essential Genome-Wide Gene Silencing Identified Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications http://hum-molgen.org/NewsGen/04-2006/msg20.html - Blood Pressure Medication May Revolutionize Treatment Of Marfan Syndrome Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome http://hum-molgen.org/NewsGen/04-2006/msg19.html - Polycomb Regulation of Embryonic Stem Cell Differentiation Polycomb group proteins play a key role in regulating vertebrate embryogenesis and in maintaining stem cell pluripotency. http://hum-molgen.org/NewsGen/04-2006/msg18.html - Apes and ApoB: systemic silencing RNAi steps closer to a clinically relevant therapy with positive outcomes in a non-human primate study via systemic delivery. http://hum-molgen.org/NewsGen/04-2006/msg17.html - Drug addiction: a hit from the genes Yale School of Medicine researchers have identified a genetic linkage for dependence on drugs such as heroin, morphine and oxycontin. http://hum-molgen.org/NewsGen/04-2006/msg16.html - Switching: a light on gene regulation Scientists have released a map of regions in the human genome that work as switches for gene regulation. http://hum-molgen.org/NewsGen/04-2006/msg15.html - Contact Genetic News editors WWW: http://hum-molgen.org/editors.html E-mail: news@hum-molgen.org DIAGnostics - Clinical Research (professional requests) http://hum-molgen.org/clinical-research/ - Post diagnostic request / call for collaboration http://hum-molgen.org/diagnostic-posting or contact admin@hum-molgen.org Biomedical Positions http://hum-molgen.org/positions/ - Biochemistry / Immunology: Sales Shanghai Hanhong Chemical Co., Ltd., Shanghai, 200237, China http://hum-molgen.org/positions/assistant/0175.html - Biotechnology: POST-DOCTORAL FELLOWSHIP INRA - Mammalian embryo nuclear architecture, Jouy en Josas, 78350, France http://hum-molgen.org/positions/postdocs/2616.html - Write a position announcement http://hum-molgen.org/flyer/positions.pdf 1) Set up account: http://hum-molgen.de/cgi-bin/positions.pl?register 2) Post position(s): http://hum-molgen.de/cgi-bin/positions.pl?login Literature http://hum-molgen.org/literature/ - Cold Spring Harbor Laboratory Press to Launch CSH Protocols Community-Driven, Interactive Methods Database set for release June, 2006 http://hum-molgen.org/literature/04-2006/msg01.html Biotechnical requests and sources http://hum-molgen.org/biotechnology Events in bioscience and medicine http://hum-molgen.org/meetings/ - Post event (free) http://hum-molgen.de/cgi-bin/meetings.pl?login Registry of Biomedical Companies (1274 active entries) http://hum-molgen.org/companies/ Mailing List Administration (Join or leave the list) http://hum-molgen.org/subscribe-na/ Feedback contact admin@hum-molgen.org Advertise at HUM-MOLGEN http://hum-molgen.org/flyer/advertise.pdf contact FS Zollmann (dialogue@hum-molgen.org) __________________________________________________________________________ RNAi Europe - Conference & Exhibition 28-29 September 2006, Prague, Czech Republic => http://hum-molgen.org/promotion-RNAi __________________________________________________________________________